查询词典 remission

AML is a clonal disease,but the clonality after remission is still contraversary,In order to analyse the clonality of haematopoiesis in AML before- and after remission,we studied the HUMARA gene polymorphism and the clonality of 30 previously untreated AML,15 AML in complete remission and 20 female cont...

急性髓系白血病是一种克隆性疾病，完全缓解后恢复正常多克隆性造血。

Background and objective Although marked progress has been made in the treatment of acute myeloid leukemia,about 20%～40% patients with AML failed to get complete remission after standard induction chemotherapy. Furthmore, approximate 70% patients in CR will die because of relapse or refractory to therapy during post remission chemotherapy.

研究背景及目的：尽管目前急性髓系白血病(acute myeloid leukemia，AML)的治疗取得了显著的进步，但仍有20％～40％的患者经标准诱导治疗未能达到完全缓解(complete remission，CR)，即使获得CR的患者，在巩固化疗后仍有70％左右复发或发展为难治性急性髓系白血病而治疗无效死亡。

Results: Among the 9 patients, two achieved completely remission, 2 achieved partial remission, 1 improved and 2 had no effect. The total response rate was 59%(5/9). The side effects were drowsiness, constipation, and debility.

结果：56%(5/9)的患者对治疗有效，其中2例为完全缓解，2例部分缓解，1例进步，2例无效；患者出现不同程度的嗜睡、便秘、头晕、皮疹等副作用。

The results showed that allergic response, diabetes and drug-induced liver disease happened more frequently during maintenance therapy than during remission induction therapy, while defibrination, abnormal hemaglutinin, acute pancreatitis, hypoproteinemia, gastrointestinal reaction and infectious shock were observed more during remission induction therapy than those at maintenance therapy.

结果表明：过敏反应、高血糖症及药物性肝炎的发生率在维持期加强治疗的ALL患儿高于诱导缓解期患儿，而低纤维蛋白原血症、凝血异常、胰腺炎、低蛋白血症、胃肠道反应及合并感染性休克等副作用在诱导缓解期患儿中发生率高。

The most commonly used drugs Bleomycin, mitomycin C, Adriamycin, 5 - 5-fluorouracil (5 - Fu), methotrexate, cyclohexyl - nitrosourea, imipramine hydrazone, Vindesine, etoposide (VP-16), chlorine and ammonia-platinum, a single chemotherapy drug remission rate in the 15% to 20% remission for 1 to 4 months.

最常用的药物有博来霉素、丝裂霉素C、阿霉素、5-氟尿嘧啶（5-Fu）、甲氨喋呤、环己亚硝脲、丙咪腙、长春花碱酰胺、鬼臼乙叉甙（VP-16），以及顺氯氨铂，单一药物化疗的缓解率在15％～20％，缓解期为1～4个月。

ResultsRenal remission achieved in six of 10 patients （60%）, partial remission in three, and unresponsive in one to LEF treatment. Gastrointestinal reaction occurred in two patients, allergy in one, transient leucopenia in one.

结果 共有6例（60%）缓解，3例部分缓解，1例无效。2例出现胃肠道反应，1例发生过敏反应，1例发生一过性白细胞下降，未见肝功能异常。

Methods Thirey-two patients treated by a regimen of Dexamethasone, Nitrogen Mustard Defibrase and Chinese medicine were not complete remission yet. These patients in remission period were applied Chlorambucil to and observed the prognosis and the drug side reaction.

32例接受正规中西医结合"四联"疗法（地塞米松、盐酸氮芥、降纤酶、本院中药制剂）后病情仍有反复的患者，在原治疗基础上于病情缓解期口服苯丁酸氮芥，临床观察病情转归情况和服药后的副作用。

Results Analysis of the expression of proteins of JAK2 in leukemic blasts, there was no detectable constitutive expression of phosphorylated JAK2 in all the AML samples analyzed; Furthermore, we could detect a constitutive activation of STAT 3 by immunoprecipitation of the targeted protein in primary leukemic blasts from 3 of 11 AML patients without any cytokine treatment; Pretreatment clinical characteristics, and treatment regimens did not differ significantly between patients with and without constitutive STAT3 activity, there was not significant relation between the constitutive activation of STAT3 and the FAB subvariety and chromosome karyotype; However, the 3 patients with constitutive STAT3 activity seemed to have adverse treatment outcome, one did not show remission, the other two patients relapsed shortly after remission; Consistent with the above-mentioned result, leukemic blasts from the 3 samples with constitutive expression of STAT3 showed higher percentage of spontaneous apoptosis and S-phase cells.

在实验研究基础上，本研究进一步运用免疫沉淀和Western Blot印迹方法，检测AML患者原代细胞JAK2和STAT3活化情况，并分析了STAT3活化与AML患者预后有关指标改变的关系。结果我们的初步研究发现，11例AML患者中，有3例呈现STAT3组成型活化（STAT3阳性，下同），无一例呈JAK2组成型活化。上述3例STAT3组成型活化与FAB分型和染色体核型改变未见明显相关性；在此3例患者中，1例未取得缓解，另外2例虽然取得短暂缓解，但均在二个月内复发。上述3例STAT3阳性AML患者S期白血病细胞百分率数值较组高，而凋亡率数值较低。

The pope cannot remit any guilt, except by declaring that it has been remitted by God and by assenting to God's remission; though, to be sure, he may grant remission in cases reserved to his judgment.

教宗不能赦免任何罪责，而只有通过宣告及肯定罪孽已由主赦免的方式来赦免人。不过他当然可以在为自己保留裁决的案件中为人赦罪。

The pope cannot remit any guilt, except by declaring that it has been remitted by god and by assenting to god's remission; though, to be sure, he may grant remission in cases reserved to his judgment.

教皇除宣告或证明罪孽已由神赦免外，他本人不能赦免任何罪过。至多仅仅有权在为自己保留裁决的案件中为人赦罪。

I'm not an actor. I'm a professor of paleontology.

我不是演员，我是古生物学教授

Spider Network Web site that is a very image of the name.

网络蜘蛛即Web Spider，是一个非常形象的名字。