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Chapter 6: Iodobenzene diacetate-mediated reactions of methylenecyclopropanes, vinylidenecyclopropanes and a methylenecyclobutane with phthalhydrazine give the corresponding [3+2] cycloaddition products in good yields under mild conditions. In these reactions, phthalhydrazine was transformed to a 1,3-dipole intermediate in the presence of iodobenzene diacetate. A plausible reaction mechanism has been proposed.

本论文对亚甲基环丙烷类化合物的一些化学反应性能进行了研究,发现了亚甲基环丙烷类化合物在不同试剂或不同催化剂作用下的一些新的化学转化并合成了一些结构简单但具有潜在应用价值的有机小分子。

Results: Kaempferol activated PXR-mediated transcription of CYP3A4 in a dose, time-dependent manner.

结果:山奈酚能通过活化PXR诱导CYP3A4的转录表达,其诱导能力随山奈酚的浓度增大和处理时间延长而呈增强趋势。

Objective This study is to investigate the effects of vitamin A level in pregnant and lactational rats on cell-mediated immunity of their offspring.

目的 研究大鼠孕期、哺乳期维生素 A水平对仔鼠细胞免疫功能的影响。

Methods:Myocyte apoptosis in patients with sudden death caused by AMI and in healthy subjects who died in traffic accident were studied by means of TdT-mediated dUTP Nick End Labeling,DNA laddering on agarose gel electrophoresis and electron microscopy.

用末端原位标记法、DNA电泳和电镜3种方法检测急性心肌梗死猝死患者和心脏正常的车祸死亡者心肌细胞的凋亡。

Treatment with dopamine and low dose bromocriptine resulted in cell death accompanied with the DNA laddering and activation of caspase-3 only in GH3D2L and GH3D2S cells, which were blunted by haloperidol, showing that dopamine-induced cell death in these cells is mediated by dopamine D2 receptors.

经多巴胺和低浓度溴隐亭处理后仅在GH3D2L和GH3D2S两种细胞中出现细胞死亡伴DNA阶梯状断裂和半胱天冬酶3(Caspase-3)的激活,而这些效应也被氟哌啶醇所抑制,说明多巴胺所致的细胞凋亡与多巴胺D2受体激活有关。

Specific primers were designed according to gene NHX1 of Limonium gmelinii published on NCBI. Then, the gene was cloned by means of RT-PCR. Eukaryotic expression vector pCAM-BIA1301-NHX1 had been constructed, then transformed into tomato by Agrobacterium-mediated transformation method. Transgenic tomatos were obtained.

根据NCBI公布的大叶补血草NHX1基因序列设计特异性引物,经RT-PCR方法克隆得到大叶补血草液泡膜Na/H逆向转运蛋白基因NHX1,构建植物融合表达载体pCAMBIA1301-NHX1,重组质粒通过农杆菌介导转化番茄,经PCR和RT-PCR鉴定,获得转基因番茄植株。

The anti-EV71 activity of the water extract of P. lobata was not mediated by interferons. In conclusion, the water extract of P.

葛根热水萃取物不会增加肠病毒71型感染产生的干扰素,因此其作用机转和干扰素无关。

Diabetic mastopathy is an uncommon condition affecting women with a history of long-standing diabetes mellitus. The observations of tumor necrosis factor and perforin reveal that cell mediated cytotoxic effects play an important role in the mechanism of this disease.

1984年Soler和Khardori首次报道糖尿病乳腺病,过去也曾被称为纤维性乳腺病、糖尿病硬化性淋巴细胞乳腺小叶炎(diabetic sclerosing lymphocytic lobulitis,DSLL)或淋巴细胞乳腺病。

We suggest that subclinical TG is an under-recognized cause of antibody-mediated, chronic renal allograft injury which may be mechanistically distinct from other causes of nephropathy.

我们认为亚临床TG是一种未被认识的抗体介导的移植肾慢性损伤的诱因,其可以独立于其他导致肾小球病的因素之外。

The melanotic phenomena mediated by PPO is widespread in both mosquitoes and other insects that being involved in sclerotization and canning of the egg shell and cuticle,wound healing and encapsulation of invading microorganisms.

目前,已从冈比亚按蚊克隆到6种不同的PPO基因,但斯氏按蚊与库态按蚊仅克隆到一种,并对其在按蚊抗疟原虫感染中的作用进行了初步研究。

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Pradeep Indulkar, a senior official at the Maharashtra state Home Ministry say 101 human were killed and 287 injured.

马哈拉施特拉邦内政部高级官员Pradeep Indulkar称,有101人在冲突中丧生,287人受伤。

Mark Frei, a senior vice president of West, says 80% of West's homeagents have some college education, compared with 30% of those whowork in office-based call centers.

Frei说,该公司80%在家办公的人员都拥有本科学位,而在公司电话中心工作的人中只有30%拥有本科学位。

Based on the application of grey forecasting control theory on the hybrid d cable-stayed bridge, the paper puts forward construct control system of the hybrid cable-stay bridge by cantilever assemble construction.

将灰色系统理论和预测控制理论应用于混合梁斜拉桥,提出了悬臂拼装施工的混合梁斜拉桥施工控制体系。