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The results showed that using the Isoflavone 50 patients with "high-sensitivity C-reactive protein" level than did patients taking the lower 37% of their "brachial artery flow-mediated vasodilation," has also been improved by 1%.

结果显示,服用异黄酮的50名病人血清內的"高敏C反应蛋白"水平,比没有服用的病人明显降低37%,他们的"肱动脉血流介导的舒张功能"也得到1%的改善。

Changes in blood flow are secondary to a relaxation of small arteries and arterioles, whilst changes in microvascular permeability, leading to inflammatory edema formation and cell accumulation, are mediated via changes that occur at the postcapillary venule level.

血管活性肽分子及其相关肽段可以内分泌的方式发挥循环激素的作用,还可以旁、自分泌的方式,通过其靶细胞表面的G蛋白偶联受体,在血管局部发挥其调节血管舒缩、细胞增殖迁移和分泌等复杂的生物学作用。

Construction yeast and plant expression vector with original gene and mutated gene, transferred into tobacco plant by electroporation and Agrobacterium mediated transformation respectively, validating genic function. Under the glyphosate pressure, the transgenic yeast strains with good tolerance are screened. The mark named ATME-4-M and ATME-9 prives the attained genes have biological function.

成功地将epsps基因构建到酵母胞内表达载体pPIC3.5K和植物表达载体PBI121上,利用电击法转化酵母及农杆菌介导法转化烟草,转基因酵母在草甘膦压力下筛选出耐受性较好的菌株,标记为ATME-4-M和ATME-9证明了所获基因具有生物学功能。

We found that ZZaPK counteracted ZAK function in cell counting assay, and restored ZAK-mediated cell cycle arrest in H460 cells.

在细胞试验的结果中可得知ZZaPK回复了ZAK所造成的细胞抑制作用,而在细胞周期的调控上也表现出类似H460正常肺癌细胞的反应。

Similarly, PV-IgG-mediated acantholysis and disruption of Dsg3 localization in HaCaT keratinocytes was partially blocked by TP.

同样,在HaCaT角蛋白细胞,串联肽部分阻断了PV-IgG介导的棘层松解和Dsg3定位的破坏。

In this study,we have ascertained AcrAB mediated multi-resistance and set up molecular detection method in Escherichia coli isolated from livestock and avian.

本研究以畜禽大肠杆菌为研究对象,确证AcrAB介导的多重耐药性,并建立分子生物学检测方法。

The result indicated: antibacterial concentration of inner thallus increased progressively with time prolongation when added CCCP with antibacteria, proved that multi-resistance of E.coli in livestock and avian is mediated really by active efflux system; The multi-resistant level have positive correlation with AcrAB transcription and expression level; Quantitive RT-PCR,Western-blotting and fluorescence quantitive PCR can use to detect AcrAB.these results provide theory foundation to detect and study multi-resistance of E.coli in veterinary clinic and have a important scientific significance to develop neotype antibacterials.

结果表明,多重耐药株在有CCCP 存在时,菌体内抗菌药物的浓度随时间的延长而递增,证明畜禽大肠杆菌多重耐药性确实由主动外排系统介导;其多重耐药水平与AcrAB的转录、表达水平呈现正相关;定量RT-PCR、Western-blotting、荧光定量PCR可用于AcrAB水平的检测。这些结果对检测临床大肠杆菌的多重耐药水平、对研究兽医临床大肠杆菌多重耐药机制提供理论依据,对开发新型抗菌药物有重要的科学意义。

Our results indicate that in Chinese Hans, common variants in CDKAL1,CDKN2A/B, IGF2BP2 and SLC30A8 loci independently or additively contribute to type 2 diabetes risk, likely mediated through β-cell dysfunction.

这些结果提示CDKAL1等基因上的SNP位点在中国汉族人群中能单独并共同地增加2型糖尿病发病风险,且可能是通过影响胰岛β细胞功能而实现的。

This suggests that neuroprotection caused by clenbuterol are mediated via β-adrenergic receptor activation.

并证明Clenbuterol的神经保护作用,是通过β2-肾上腺素能受体的激活来完成。

Binding of the P2Y12 receptor by its agonist, ADP, activates the G-protein inhibitor secondary messenger system, which, through a complex series of events, mediates the completion and amplification of the aggregatory response.7 Ticlopidine and clopidogrel are prodrugs that are converted to an active metabolite through a 2-step process mediated by the hepatic cytochrome ...

氯吡格雷和抵克立得作为药物前体,都可通过肝脏细胞色素P450介导的两步反应过程转化为活性代谢物…。。

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