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The proliferation of SGC-7901 cell line was markedly inhibited by shRNA-GC-CⅢ（ P .05）. There was changes in cell morphology, such as cell volume reduction, karyopyknosis and chromatin conglomeration. FCM showed that GC-C inhibition caused the appearance of sub-G 0 /G 1 peak which increased from 5.47%（48h after transfection） to 5.63%（72h after transfection）.

转染GC-C shRNA真核表达载体后SGC-7901细胞的增殖能力受到抑制（ P 。05）；细胞形态发生改变，细胞体积缩小，核固缩，染色质浓缩聚集于核膜；流式细胞术检测显示G 1 峰前出现亚二倍体峰，转染48、72h后凋亡率分别为5.47%和5.63%（ P nbsp； 0.05）。

As to'Cabemet Sauvignon'and'Queen of Vineyard', which belong to the'West Europe Cultivars Group', no obvious decline of Fv/Fm was found in their potted plants even under severe drought stress. Their photosynthetic abilities also greatly recovered after rewatering, i. e. no serious photodamage was formed in these cultivars under drought stress. Between them, the φPSⅡ of 'Queen of Vineyard'under severe drought stress was much lower than that of'Cabernet Sauvignon', which suggested that the light use efficiency of the former was much lower than the latter under severe drought stress. The potted plants of'Autumn Royal'and'Rizamat' sustained high Fv/Fm and φPSⅡ before moderate drought stress, but seriously declined under severe drought stress, which indicated that these cultivars had a weak resistant ability to extreme drought stress. A hybridized cultivar of Vitis vinifera L. and V. labrusca L.,'Red Double Taste', its Fv/Fm and φPSⅡ expressed mild decline along drought stress grade.φPSⅡ of'Red Double Taste'was the highest among seven cultivars under severe drought stress condition, which might closely connected with its high photorespiration activity. Another new cultivar,'Red Globe', and a rootstock,'1103Paulsen', the Fv/Fm and φPSⅡ of their potted plants declined markedly under slight drought stress, which suggested that they held a weak ability to defend against photoinhibition.

西欧品种群的赤霞珠和葡萄园皇后，其盆栽苗的Fv／Fm直到重度干旱胁迫下仍没有明显的降低，且复水后光合能力恢复程度较高，即干旱没有给这两个品种造成严重的光破坏，而两个品种之间，葡萄园皇后在重度干旱胁迫下的φPSⅡ明显低于赤霞珠，说明其光合器官在严重干旱胁迫时对光能的利用率较差；新品种皇家秋天和东方品种群的里扎马特在中度干旱胁迫下仍可维持较高的Fv／Fm和φPSⅡ，但在重度干旱胁迫下则降低幅度较大，说明其抵御极端干旱胁迫的能力较差；欧美杂种红双味的Fv／Fm和φPSⅡ随着干旱胁迫程度的增加呈现平缓的下降趋势，而且其φPSⅡ在重度干旱胁迫下是七个品种中最高的，这应该与其此时仍维持较强的光呼吸活性有关；红地球和砧木1103Paulsen的Fv／Fm和φPSⅡ在轻度干旱胁迫下就明显下降，表明干旱条件下其抵御光抑制的能力较差。

Along with seawater stress strength upward, the ratio of root to shoot, Na+, Cl- and soluble sugar contents were increased significantly. Under the 10% and 20% seawater treatments, chlorophyll contents have no obvious difference compared with the control, but significantly decreased when the seawater stress further increased. Under the 10% seawater treatments, K+ contents in the shoot and root of Lactuca indica seedlings have no distinct difference compared with the control, but along with seawater stress strength upward, K+ content were markedly decreased by degrees. However, soluble protein content first increased then decreased with seawater concentration augment.

结果表明：苦荬菜幼苗地上部受海水胁迫较为显著，而根在30%海水以内与对照相比没有显著差异；根冠比随着海水比例的增加而提高；10%和20%海水处理下，叶绿素含量与对照相比差异不显著，但随着海水浓度的进一步增加，叶绿素含量显著下降；10%海水处理下，苦荬菜地上部分及根K+含量与对照差异不显著，高于10%海水处理，K+含量随海水比例的增加地上部和根部均逐渐显著降低；海水处理下，体内Na+和Cl-含量逐渐显著增加；地上部可溶性糖逐渐显著增加，而可溶性蛋白呈先升后降。

NOS neurons atrophy markedly in laterodorsal tegmental nucleus of aged mice. NOS neurons and synapses atrophy in Alzheimer's disease patient temporal cortex and amygdala, NOS neurons decrease by 18-33% in hippocampus.

衰老时NOS神经元发生了某些变化，老龄小鼠被盖背外侧核NOS神经元明显萎缩；Alzheimer's病人颞叶皮层和杏仁核NOS细胞及突触显著绉缩，海马分子层内侧1/3缺少NOS神经元，NOS神经元减少18～30%。

Twelve hours latter,uterine vessels formation was revealed by tannin-Fe lavement solution.Results The uterine vessel formation of rats in the model group showed that varices,tetanic shape,the density of all levels vessel net increased obviously and its twist,serpentine shape decreased markedly,while that in the large,middle dosage Gongning groups displayed absolute contrarily and fit like a glove with the normal control group.The uterine vessel formation of rats in the small dosage Gongning group and indomethacin group also showed the same transformation as it in the model group.

结果 模型组大鼠子宫各级血管扩张增粗，走行僵直，螺旋状和蜿蜒状走行消失或明显减少，血管形成的各级血管网密度增加，分布不均；消炎痛组、宫宁小剂量组子宫血管仍存在较明显的血管腔扩大、走行僵直和血管网密度增加，宫宁大、中剂量组子宫血管构筑的异常改变消失或明显改善。

This is an example of linitis plastica , a diffuse infiltrative gastric adenocarcinoma which gives the stomach a shrunken "leather bottle" appearance with extensive mucosal erosion and a markedly thickened gastric wall.

图示为革囊胃，是由于胃腺癌的广泛浸润而使胃缩小似革囊外观，胃黏膜广泛被侵蚀，胃壁明显增厚。

Electrocardiogram abnormal rate of stroke in brain stem was most high,but it was not markedly high compared with stroke in lobar.

老年急性脑卒中的心电图改变与卒中性质、范围及部位有关，也与卒中的严重程度一致。

The Th1/Th2 ratio was decreased markedly in uremic patients (P＜0.05). Conclusions Uremic patients showed Th2 predominance. LYmphopenia and Th1/Th2 imbalance may contribute to the immuno-insufficiency in HD patients.

尿毒症患者T细胞亚群表现为Th2优势，透析患者存在B淋巴细胞减少，淋巴细胞亚群的这些改变可能参与了血液透析患者免疫功能下降的发病机理。

Lymphocyte shuttling between blood and lymphy organ is the substance to keep immune stabilization, perform their immune defence and immune surveillance, If there have markedly change on lymphocyte function and amount, which can be thought immune disorder, which associated with clinical disease.

穿梭在血液与淋巴器官中的淋巴细胞是维持机体免疫稳定，执行免疫防御、免疫监视功能的物质基础。

TSRP could decrease brain hydrated amount and markedly lower permeability of blood-brain barrier subjected to 2 h MACO followed by 24 h reperfusion, and this may be a mechanism of TSRP alleviating brain edema during I/R.

茅莓总皂苷各剂量组显著降低缺血2h再灌注6，24，48，72 h脑水肿和其对血脑屏障通透性，这可能是其减轻I/R时脑水肿的机制之一。

If you were not , and OS X just booted normally, have no fear.

如果你没有，和OS X刚刚启动通常，没有恐惧。

I only want to preserve our all .

我只想保存好我们的一切