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Objective To explore livin, MTA1 and the caspase3 protein expression, their correlation and clinical pathology in colon cancer Methods The expressions of livin, MTA1 and caspase3 protein in 88 cases of colon cancer were detected by immunohistochemistry stainingResults Livin, caspase3 protein and MTA1 positive expression rates in colon cancer tissues were more than those in tissues beside the cancer Furthermore there were obvious relevance between livin protein, MTA1 positive expression rate and degree of histodifferentiation and lymph node metabasis and between caspase3 protein positive expression rate and degree of histodifferentiation of colon cancer Caspase3 protein expression had prominent inverse correlation with the livin expressionConclusions ①Over expression of livin having inhibtion on colon cancer is one of important factors of colon carcinogenesis ②Caspase3 protein expression in colon cancer tissues is inhibited to less and has prominent inverse correlation with livin expression Accordingly, suppressing caspase3 protein activity is one of channels, by which livin promotes colon carcinogenesis ③MTA1 plays the important role in histodifferentiation degree and lymph node metastasis of colon cancer

采用免疫组织化学染色方法检测88例结肠癌组织中Livin,Caspase3 及MTA1的表达情况。结果(1)结肠癌组织中Livin的阳性表达率显著高于癌旁组织,且Livin的表达与结肠癌的组织分化程度及淋巴结转移程度显著相关。(2)结肠癌组织中Caspase3蛋白的阳性表达率显著高于癌旁组织,且Caspase3蛋白的表达与结肠癌的组织分化程度显著相关。(3)结肠癌组织中MTA1的阳性表达率显著高于癌旁组织,且MTA1的表达与结肠癌的组织分化程度及淋巴结转移程度显著相关。(4)Caspase3蛋白的表达又与Livin的表达呈显著负相关。结论(1)Livin在结肠癌组织中过表达,它可能是促进结肠癌发生的重要因素之一。(2)Caspase3蛋白在结肠癌组织中表达被抑制而降低,且与Livin的表达呈负相关。因此,抑制Caspase3蛋白的活性是Livin促进结肠癌发生的途径之一。(3)MTA1对结肠癌的组织分化及淋巴转移发挥重要作用。

Based on inverse equation, the forward solution model of position is presented in this thesis through method of successive approximation, for parallel robots possess characteristic of easy inverse solution and difficult direct solution. The method is proved to be highly effective by simulation example.

根据6-SPS并联机器人反解容易、正解较难的特点,本论文基于位置反解方程,通过杆长逐次逼近的思路建立了位置正解模型,并对该方法进行了实例验证。

This thesis is divided into six parts. The first chapter is preface, the current status of research in the inverse problems for parabolic partial differential equations is reported; the second chapter is "regularization methods for numerical differentiation and their applications ", in this chapter we investigate many regularization methods from a viewpoint of regularization theory and algorithm, some applications in the inverse problems for parabolic partial differential equations are given; the third chapter is "spectral regularization methods". Based on Fourier analysis, within the framework of regularization theory, we apply the spectral methods to some ill-posed problems. Many numerical experiments are done in order to show the validity of the methods; the fourth chapter is devoted to wavelet dual least squares method and a revised wavelet method; in the fifth chapter,we combine finite difference method with method of lines and apply it to the backward heat conduction problem in time; in the sixth chapter "identification problems for unknown source ", the essence and the degree of two problems related to source identification are pointed out, at the same time, some numerical methods are reported.

本文分为六个部分,第一章前言简要分析了国内外抛物型偏微分方程反问题的研究现状;第二章数值微分的正则化及其应用从正则化理论和算法的角度出发,考察了许多正则化方法,还给出了数值微分在抛物型偏微分方程反问题的一些应用;第三章谱正则化方法是在Fourier分析的基础上,在一般正则化理论的框架下,给出了这种方法在各种不适定问题中的应用,数值实验表明谱方法是有效的;第四章研究了小波对偶最小二乘方法和改进的小波方法;第五章主要研究了有限差分方法结合线方法在时间反向热传导问题中的应用;第六章是未知源识别问题,主要指出了两类未知源问题的不适定程度和不适定本质,同时报告了一些数值方法。

By using the graph-theoretic method, the completion problems for a partial inverse Mmatrix with any order are discussed when its corresponding graph of the partial inverse M-matrix is a 2-chordal graph .

本文采用图论的方法对任意阶部分逆M矩阵,当其对应的图为2-弦图时,研究了其逆M矩阵的完备问题。

In this paper, we study a class of inverse M-matrices and inverse Z-matrices of tree structure, which have much value in application and theory and matrices associated with the original matrices, for exmple Schur complements, Perron complements, ect.

第二章主要研究一类树结构逆M、逆Z矩阵,图的理论和方法被应用于矩阵结构和性质的研究,图的理论和矩阵理论有着密切的关系,并且图理论用于矩阵的研究有着直观、简洁的特点,二者的研究具有互补的关系,用图的理论和方法研究矩阵一直是矩阵理论研究的一个重要方向。

In this chapter, we show that Perron complements of N_0~2-matrices are N_0~2-matrices. We also demonstrate the Perron complements of inverse N_0~1-matrices are inverse N_0~1-matrices with certain restriction.

第四章研究非严格广义双对角占优矩阵的Schur余的性质,对角占优矩阵是数值计算中经常遇到的一类矩阵,它的Schur余可应用于迭代法的构造。

The method comprises the steps: S402: an inverse process multiplexing for a terminal to transmit channels; S404: CRC verifies a statistical module and judges whether CRC verified calculation in the inverse process is right and after relevant processing is taken according to the results of the judgment, the right circumstances in the CRC verification in the reverse process are added up; S406: the terminal outputs the link quality of the transmission channels according to the stastical results of the verified statistical module in the CRC; S408: RNC sends out request message for counting, and the terminal makes response to the counting in pre-set conditions and feedbacks the link quality of the transmission channels; S410: after receiving the counting response of the preset quantity, the RNC counts the link quality given feedback by the terminal and confirms whether to regulate power allocation of the signal channel loading MBMS according to the statistical results.

本发明提供了一种采用外码增强技术反馈链路质量的功率分配调整方法包括:S402,终端进行传输信道复用的逆过程;S404,CRC校验统计模块判断逆过程中的CRC校验计算是否正确,并且在根据判断结果进行相关处理后,统计逆过程中CRC校验的正确情况;S406,终端根据CRC校验统计模块的统计结果输出传输信道的链路质量;S408,RNC发送计数过程请求消息,并且终端在预定条件下响应计数,并反馈传输信道的链路质量;S410,RNC在接收到预定数量的计数响应后,统计终端反馈的链路质量,并根据统计结果确定是否调整承载MBMS的信道的功率分配。

We obtain some neccessary and sufficient conditions of reverse order laws for g-inverse and reflexive g-inverse of matrix products on an arbitrary skew field.

获得了任意体上矩阵乘积的g一逆和自反g-逆的反序律的充分必要条件。

Based on the research of some recent algorithms work of the initial solution estimation of inverse simulation approach,an improved algorithm,named projecting and averaging linear deformation method,is presented,which enables the inverse approach more stable and improves its convergence greatly.

初始解的确定是板料冲压成形有限元反向分析中的一个重要环节,初始解的好坏会影响后续计算的收敛性以及分析计算的效率。

And the sufficient and necessary conditions are obtained and the uniqueness of T is discussed and an algorithm for solving the inverse problem is provided. The other kind of structure inverse eigenvalue problem is for unitary Hessenberg matrices with positive subdiagonal elements. That is, a unitary Hessenberg matrices with positive sub-diagonal elements can be constructed when its eigenvalues and the eigenvalues of H_(11) and H_(22) are known. Here H_(11) and H_(22) are rank-one modifications of k × k leading principal submatrix of H and of its × remain submatrix respectively. In the end, the uniqueness of H and an algorithm is obtained.

文中首先讨论了这三组特征值之间的交错关系,接着确定了该逆问题有解的充要条件,并论证了其解的唯一性问题,最后给出了相应的数值算法;本文第二个问题解决的是一类不可约的酉Hessenberg阵的逆特征值问题:即一个不可约的酉Hessenberg阵可以由它的特征值、它的前k阶秩一修正的顺序主子阵的特征值以及它的后n—k阶余子阵的秩一修正阵的特征值来确定,文中最后讨论了唯一性和相应的算法。

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He and Nina moved to California and lived at 2005 Ivar Street, Apt.

他和Nina搬到加州,并在2005年伊瓦尔街,公寓生活。

Droperidol ( potently inhibits transfected HERGchannels and this is the probable mechanism for QT prolongation.

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The Nazi's cruel treatment of the Jews during the Second World War is beneath contempt .

二战期间纳粹对犹太人的暴行极其可鄙。