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The associated audiologic features included progressive, prelingual, bilateral moderate to severe sensorineural hearing loss with a flat-type audiogram configuration. Among the probands of the 17 AN families enrolled for genetic study, mutations in OTOF gene were identified in 3 (18%) probands.

连同他院转介之病例共计22例，其听力丧失形式大部分为习语前、渐进性、两侧对称之感觉神经性听障，纯音听阈为正常至重度听损皆有，听力图图形多为平坦型，且颞骨之高解析度电脑断层扫瞄检查结果大部分为正常。

In 1887 H. Hertz identified the photoelectric effect. In 1907 De Forest patented the audion, or triode.

1887年，H。赫兹发现了光电效应。1907年，德福来斯特发明的三极真空管获得专利。

The common method, that all strong-correlation terms of the model are eliminated, can bring the loss in the engineering application, so the new method is proposed that the identified model reserves some correlation. The augmented matrix A is constructed by the outputΔW and the matrix S. The"determinating order based on ratio of determinant"is brought out to screen the strong-correlation terms in the structure identification. The latent root estimation is improved in screening the eigenvalues and eigenvectors. Thus the estimation precision is improved greatly.The consistence check of guidance instrument error coefficients of flight test and ground test is the purpose of flight experiment. The causes of inconsistency of the two models are analyzed. The hypothesis test of linear regression model based on F statistics is proposed to check the consistence.Finally, the instability of error coefficients is probably caused by the change of the flight environments, therefore, the relation between the error coefficients and flight environment is analyzed. The approach is presented to identify SINS guidance instrument error models and compensate the error in the segmented sections corresponding to the change of vertical acceleration of aircraft.

在结构辨识中，常用的方法由于将模型中的强相关项全部剔除而给工程应用带来损失，因此，本文提出了新的有益思想，即在保留一定相关性的基础上进行辨识：将输出向量ΔW与环境函数矩阵S构成增广矩阵A，然后采用"比定阶行列式"来剔除相关向量的方法，这样既可以尽可能多地保留了对落点影响大的强相关参数，又可以对落点影响小的强相关参数给予剔除；在参数估计中，改进了特征根估计中特征根和特征向量的筛选方法，提出"近零"准则，从而大大提高了参数估计的精度；再者，鉴于天地模型"一致性"检验是飞行试验和SINS制导工具误差系数分离的主要目的，因此，本文又深入分析了造成天地模型不一致的原因，提出了采用基于F统计的线性回归模型假设检验方法来进行捷联制导工具误差模型的天地"一致性"检验；最后，鉴于飞行环境剧烈变化可能会对惯性仪表误差系数稳定性带来一定的影响，因此本文深入地分析了SINS制导工具误差系数与外界环境的关系，提出了基于过载变化大小的分段辨识和分段实时补偿的算法。

Objective It was reported that rALR (rat augmenter of liver regeneration) distribute in most of tissue and organ of rat, no-tissue specility; mRNA expression of rALR was identified variedly in different tissue, strongest in testis. But nowadays there was not some study on ALR in rat testis. Here to confirm the expression and localization of ALR in infancy,adult and old rat testis,comparing the change of ALR expression degree before per 70 PH and after per 70 PH. In order to evaluate expression principle of ALR in rat testis and know if ALR has tight connection with spermatogenesis and development of testis, to explore the relation between ALR and reproduction, to discover the possible expression character and functional methods of ALR.

目的：文献报道rALR分布于各组织器官，无组织特异性，但其mRNA在各组织的表达强度有差异，在睾丸组织表达最强，目前对大鼠睾丸ALR表达尚无深入的研究；本实验研究不同年龄段大鼠睾丸组织中肝再生增强因子的表达水平、表达部位、以及表达的方式，进而探讨睾丸ALR与睾丸发育、精子生成以及生殖活动的关系；同时探究睾丸组织ALR表达是否参与了肝脏的再生过程中，进一步了解睾丸ALR表达的特性及作用方式。

Auguste D would be the first patient to be identified with Alzheimer's disease.

D女士便是第一位被指出有阿兹海默症的病人。

The informational object authoring and distribution system functions to provide Value-Added Material Safety Data Sheets via the use of a centralized repository of uniquely identified, immutable Material Safety Data Sheets.

一种通过使用集中化注册的唯一标识的不可改变的材料安全数据表来提供增值的材料安全数据表的信息对象编辑和分配系统。

Authoritarianism was identified shortly after the second world war as part of research to discover the causes of fascism.

独裁主义在二战后不久就作为研究的对象，来分析法西斯主义产生的原因。

Even though a lot of research has been done, there is no identified single factor that causes Autism.

即使大量的研究已经完成，是没有确定的单一因素导致自闭症。

Methods The clpE-deficient strain was constructed by LFH-PCR and identified by PCR and sequencing. The impact of clpE mutant on the virulence of S. pneumoniae was evaluated in a mouse model. In addition, we also studied the effect of clpE mutant on adherence and invasion of host cells. Real time RT-PCR was used to measure the mRNA expression levels of autolysin A, pneumococcal surface adhesion A, pneumolysin, pneumococcal surface protein A and neuraminidase The clpE gene was replaced completely by erm cassette.

用长臂同源多聚酶链式反应方法失活clpE基因，用PCR、测序鉴定缺失菌株，通过动物实验观察clpE基因缺失株毒力改变情况，同时用细胞实验比较clpE基因缺失株和野生菌对宿主细胞的粘附和侵袭能力，最后用实时荧光定量PCR分析自溶素(major autolysin A，lytA)、表面黏附素A(pneumococcal surface adhesion A，psaA)、溶血素(pneumolysin，ply)、肺炎球菌表面蛋白A（pneumococcal surface protein A， pspA和神经氨酸酶（neuraminidase， nanA）的表达。

In the present study,using PCR amplification and automatic sequencing of EDA gene coding region,we report five mutations identified in 6 Chinese families with XLHED, including three novel ones:p.M1T,p.L62P and

其中3个点突变(p.M1T、p.L62P和p.G195E)为国际首次报道的新突变。

It's bell can reach over a meter in diameter.

它的身体最大可以达到直径1米多。

Now they are overdue and I shall have to pay a fine.

现在他们过期了，我不得不付罚款。