查询词典 epi-position

The growth inhibiting rate of T24 cell lines were detected by MTT methods, apoptosis of cells were detected by flow cytometry, the mechanism of apoptosis was analyzed by detecting the protein expression of Bcl-2, Bax, Caspase-9, Caspase-3 and cytoplastic protein Cytochrome C. 4 We injected live T24 cells into the subcutaneous space of nude mice and successfully built up the animal model of bladder carcinoma. The effect of CS-PAA-EPI polymer magnetic microspheres targeting chemotherapy was investigated by HE staining, TUNEL ,tumor weight and volume inhibition rate. Results: 1 TEM revealed that the CS-PAA polymer magnetic microspheres were regular spherical shape,the average diameter was 80nm in dry condition. By controlling the pH value of the medium,polymers had positive or negative zeta potential. VSM showed the CS-PAA polymer magnetic microspheres had superparamagnetic. The diameter of CS-PAA-EPI polymer magnetic microspheres were 200nm in solution by DLS examining,the embedding ratio was 20%,the EPI loading rate was 15%, which was higer than reported in other articles. 2 Raw eye observation found that the rat"s bladder of treatment group was brown color,which meaned the aggregation of iron particles, compared with the control group, iron stain found iron particles were assembled in rat"s bladder of the treatment group, the amount of iron particles in liver and spleen were less obviously.

研究结果：1合成的CS-PAA磁性聚合物微球呈球形，大小均一，TEM测定其干态下粒径为80nm左右，磁化曲线证实具有超顺磁性，具有一定的PH敏感性，固载表柔比星后，水溶液性状稳定，无沉淀物，DLS测定直径约200nm左右，测定载药率为15％，较文献报道高，包封率为20％。2肉眼观察试验组大鼠膀胱表面呈褐色，可见大量的Fe粒子聚集，普鲁士兰染色法显示，试验组大鼠膀胱壁内有大量的Fe粒子，分布至膀胱壁全层，与对照组大鼠相比，试验组大鼠的肝、脾内的Fe粒子聚集量明显降低；HPLC测定结果与Fe染色相同；高剂量磁性CS-PAA-EPI生理盐水组及单纯EPI生理盐水组均在给药后14天出现血肌酐和尿素氮的升高，其他组大鼠血生化指标没有明显变化。3MTT法发现，高、中、低剂量磁性CS-PAA-EPI生理盐水组在外加磁场的协同作用下杀伤T24细胞效应明显高于单纯的EPI生理盐水组，FCM发现试验药物组可引起明显的肿瘤细胞凋亡，试验药物治疗组细胞胞浆内出现了由线粒体释放出的细胞色素C，试验组细胞Bcl-2蛋白减少，Bax蛋白变化不明显，Caspase-3、Caspase-9蛋白受到了激活活化。4高、中、低剂量磁性CS-PAA-EPI生理盐水组的瘤重抑制率和瘤体积抑制率均明显高于单纯的EPI生理盐水组(P＜0.01)，其中高剂量组的抑制率最高。

The complexity of this idea is reflected in the variety of constructions used with the verb (a hoti clause, or accusative and infinitive, expressing truth believed; en and epi with the dative, denoting restful reliance on that to which, or him to whom, credit is given; eis and, occasionally, epi with the accusative, the most common, characteristic, and original NT usage, scarcely present in the LXX and not at all in classical Greek, conveying the thought of a move - ment of trust going out to, and laying hold of, the object of its confidence).

的复杂性，这一主张是反映在各种建筑用的动词（一霍蒂条款，或accusative和不定式，表示相信真理； EN和计划免疫与格组成，代表宁静的依赖，为这，还是他的人，信用是鉴于； EIS的，偶然计划免疫与accusative ，最常见的，特点，以及原新台币使用，目前几乎在lxx并没有这回事，在古典希腊语，传达思想的举动-m ent信托走出去，并铺设举行的，该物体的，其可信度）。

Containing many T cell epi-positions and neutralizing antibody epi-positions, the core protein region and envelope protein 2 of Hepatitis C virus structural protein may induce protective immunity responsion in body.

丙型肝炎病毒(hepatitis C virus，HCV)结构蛋白的核心蛋白和包膜蛋白2(E2)含有多个T细胞表位和中和抗体表位，可诱导机体产生保护性免疫应答。

ASES is 59% identical to Artemisia cyclase cDNA clone cASC125, 50% identical to epi-cedrol synthase from A. annua, 48% identical to amorpha-4, 11-diene synthase from A. Annua, 39% identical to the 5-epi-aristolechene synthase from tabacco, 38% identical to vetispiradiene synthase from H. Muticus, 41% identical to the δ-cadinene synthase from cotton. The coding region of cDNA was cloned into procaryotic expression vector pET30a and overexpressed in E. coli BL21 (DE3). The cyclase proteins extracted from bacterial culture were found largely in the insoluble protein fraction. The tissue specific expression patterns were analyzed by RT/PCR.

克隆的倍半萜合酶氨基酸序列与烟草马兜铃烯合酶、莨菪岩兰螺旋二烯合酶、棉花杜松烯合酶的一致性分别为39％，38％和41％；与青蒿柏木脑合酶、紫穗槐二烯合酶和一个推测的倍半萜合酶克隆cASC125的一致性为50％，48％和59％。cDNA编码区序列被克隆进原核表达载体pET-30a，并在大肠杆菌BL21（DE3）中诱导表达，但过量表达的蛋白主要是以不溶性蛋白形式存在。

At last,a convergent and general protocol to marine natural product,as demonstrated by the enantioselective total synthesis of malyngamides O,P,Q,R, 5"-epi-Q and 5"-epi-R bearing terminal vinylic chloride structure,was developed in detail.E,(7S)-7-methoxytetradec-4-enoic acid was prepared using the above described Johnson-Clainsen rearrangement,the terminal vinyl chloride was constructed using Wittig reaction as key step,the pyrrolidone derivative was constructed using L-serine as natural chiral pool.Starting from the synthesis of malyngamides O and P to explore the general route,an aldol reaction of methyl acetate with the vinyl chloride part in the presence of LDA gave the skeleton of amine portion,followed by amidation with the fatty acid finished the synthesis of malyngamide P.

先以malyngamides O和P为试点探索通用合成路线，将乙酸甲酯和烯氯部分在LDA存在下进行aldol反应得到氨部分的骨架，再将手性不饱和脂肪酸和氨部分进行酰胺化反应完成了malyngamide P的合成，将P在碱性条件下进行烯醇甲基化反应完成了malyngamide O的全合成。

The complexity of this idea is reflected in the variety of constructions used with the verb (a hoti clause, or accusative and infinitive, expressing truth believed; en and epi with the dative, denoting restful reliance on that to which, or him to whom, credit is given; eis and, occasionally, epi with the accusative, the most common, characteristic, and original NT usage, scarcely present in the LXX and not at all in classical Greek, conveying the thought of a move - ment of trust going out to, and laying hold of, the object of its confidence).

的复杂性，这一主张是反映在各种建筑用的动词（一霍蒂条款，或accusative和不定式，表示相信真理； EN和计划免疫与格组成，代表宁静的依赖，为这，还是他的人，信用是鉴於； EIS的，偶然计划免疫与accusative ，最常见的，特点，以及原新台币使用，目前几乎在lxx并没有这回事，在古典希腊语，传达思想的举动-m ent信托走出去，并铺设举行的，该物体的，其可信度）。

In the presently mobile position technology, GPS's position method is one of the best. This method owns high accuracy less than 15 meters, and can be used with GPS chip in the mobile station. But GPS chip with the high price makes this technology difficult to popular. Therefore, the position technology of GSM communication network is attention to the people gradually. TOA or AOA is more often used among position technology, these methods need only the help of the position measuring instrument to attain time and angle for position calculation. They have good position accuracy, but they are also too expensive to popular. Every positioning technology has its bottleneck such as external environment influence, cost and positing efficiency. Therefore, the purpose of this research lies in finding out the mobile station location and does not emphasize the raise of the accuracy and it only uses existing information to finish position action.

在目前的行动定位技术中，以GPS定位技术为最佳，不仅拥有少於15公尺的高定位精确度，更只需在行动端加装GPS晶片即可使用，可惜高价格的GPS晶片使得此技术难以普及化，因此，以GSM通讯网路为主的定位技术逐渐受人们所重视，其中，又以TOA或AOA等定位技术较常被使用，仅透过位置测量仪器的帮助，便可取得定位所需的时间和角度，并且拥有不错的定位精确度，可惜也受到高价格因素的关系难以普及化，而每种定位技术都有其瓶颈存在，不论是外在环境的影响、成本和定位效能上；所以，本研究的目的在於找出行动端位置，即利用现有的资讯（细胞识别码、讯号强度等）来完成定位动作，而非强调其定位精确度的提高。

A hammer drill, in particular a chipper comprising: a body 2 having at least one support handle 4; an electric motor mounted within the body 2 ;an electric switch 22, capable of being switched on and off by a trigger button 8 connected to it, to activate or deactivate respectively the electric motor, wherein the trigger button 8 is moveable between two positions, a first position where the electric switch 22 is off and a second position where the electric switch 22 is on; a locking arm 38 moveably mounted on the electric switch 22 which, when the trigger button 8 is located in its second position, is moveable between two positions, a first position where it is disengaged from the trigger button 8 and a second position where it engages with the trigger button 8 and holds the trigger button 8 in its second position.

锤钻特别是錾，包括：本体(2)，该本体(2)具有至少一个支撑手柄(4)；安装在本体(2)内的电动马达；电开关(22)，该电开关(22)能够由连接到电开关(22)上的触发按钮(8)接通和断开，从而分别使电动马达启动或停用，其中该触发按钮(8)能够在两个位置即第一位置和第二位置之间移动，在该第一位置处电开关(22)断开，在该第二位置处电开关(22)接通；可移动地安装在电开关(22)上的锁紧臂(38)，当触发按钮(8)位于它的第二位置中时，该锁紧臂(38)能够在两个位置即第一位置和第二位置之间移动，在该第一位置处锁紧臂(38)与触发按钮(8)脱离，在该第二位置处锁紧臂(38)与触发按钮(8)接合并将触发按钮(8)保持在触发按钮(8)的第二位置中。

The hanging strip device includes: a hanging strip device main body; a winding section for performing the winding of the hanging strip; a winding auxiliary section, which is configured at a state that the rotation relative to the hanging strip device main body is limited and can move between the first preset position and the second preset position relative to the winding section, wherein, at the first preset position, the rotation of the winding section makes the hanging strip wrap is restricted, at a second preset position, the winding section can perform the drawing-out rotation for drawing out the hanging strip; a force applying part, which applies a press pressure to make the winding auxiliary section at the first preset position; and a convex part which allows the winding auxiliary section to be at preset point contact status relative to the hanging strip device main body when the winding auxiliary section is at the first preset position.

置在该吊带装置主体内，而且能够在第一预定位置和第二预定位置之间相对于上述卷绕部移动，其中，在上述第一预定位置，上述卷绕部的使上述吊带回绕的旋转被限制，在上述第二预定位置，上述卷绕部能够进行用于抽出吊带的抽出旋转；施力部，其施加将上述卷绕辅助部按压向上述吊带装置主体的按压力，以使该卷绕辅助部处于上述第一预定位置；和凸起部，其设置于上述卷绕辅助部或者上述吊带装置主体的任一方，在该卷绕辅助部处于上述第一预定位置时，上述凸起部使该卷绕辅助部相对于上述吊带装置主体成为预定的点接触状态

The therapeutic efficacy in posterior extension sitting position occupying 11-20° was better in upper hind neck; the therapeutic efficacy in anteversion sitting position occupying 11-20° was better in inferior neck; the therapeutic efficacy in anteversion sitting position occupying 1-10° was better in neutral position sitting position.

即上颈段椎动脉型颈椎病患者坐位后伸11°~20°牵引疗效较好，下颈段椎动脉型颈椎病患者坐位前屈11°~20°牵引疗效较好，混合型椎动脉型颈椎病患者坐位前屈1°~10°疗效较好。

For every one of my New Year resolutions, I have been a backslider for years.

说到我的新年决心，我每年都做

With empathy and focus on a feeling level, we can all relate to the common ground of mutuality of emotions.

有了同情心和感觉上一级的重点，我们都可以涉及到相互的情感共同点。