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Results:①The amount of human colon carcinoma cell line SW480 treated by quercetin decreased. The morphology of partial SW480 cells was shrunk volume, integrated cell membrane, condensed cytoplasm, pyknotic chromatin, nuclear fragmentation. Apoptotic Corpuscles were found by electron microscope.②MTT colorimetric assay showed quercetin inhibited the growth of human colon carcinoma cell line SW480 in a time- and dose-dependent manner when the concentration of quercetin was 30、60、90μmol/L.③Flow cytometry analysis showed the cell cycle of SW480 cell was restricted in G1/S. G0/G1 phase rate increased and S phase rate decreased with increasing concentration of quercetin and time lasting.④ Zymogram analysis assay showed the secretion of matrix metalloproteinases in human colon carcinoma cell line SW480 treated by quercetin decreased. With increasing concentration of quercetin, the secretion of MMP-2 and MMP-9 decreased.⑤Immunohistochemistry method demonstrated the position expression of Cathepsin-D in SW480 cell was suppressed by quercetin in a time- and dose-dependent manner.

研究结果：经槲皮素处理的人结肠癌SW480细胞数量减少，部分细胞体积缩小，细胞膜完整，胞浆浓缩，核染色质固缩，细胞核碎裂，形成凋亡小体；MTT法检测显示当作用浓度为30μmol/L~90μmol/L时，槲皮素对人结肠癌SW480细胞的生长有抑制作用，其抑制作用随着作用浓度的增加和作用时间的延长而增强；流式细胞学发现槲皮素主要作用于人结肠癌SW480细胞周期的G1/S期，大部分细胞被阻断于S期，随药物浓度的升高和作用时间的延长，G0/G1期细胞比例逐渐增加，S期细胞比例逐渐减少；酶谱分析法检测显示不同浓度的槲皮素能够抑制人结肠癌SW480细胞分泌MMP-2及MMP-9，随浓度的升高，MMP-2及MMP-9的分泌量减少；免疫组织化学法显示不同浓度的槲皮素处理人结肠癌SW480细胞后，Cathepsin-D的表达随药物浓度的升高和作用时间的延长而降低。

The concentration of enantiomers was positively related to the maintenance dose of warfarin, but not to drug response. It is not applicable to adjustment of the dose by monitoring the concentration of racemic warfarin, or to its enantiomers.

异构物浓度与维持剂量间有显著的相关性存在，但与疗效间却没有直接的相关，故无法以监测浓度的方式来调整病患之剂量，仍需采用临床上使用的INR值来监测。

Rats in control group and model group received 0.9% sodium chloride solution 10 mL/kg. Rats in compound danshen dripping pills group received 0.75% compound danshen dripping pills 10 mL/kg. Rats in Xintongzhi drop pill high dose group and Xintongzhi drop pill low dose group received 3.6%, 1.8% Xintongzhi drop pill 10 mL/kg, respectively. After 7 days except control group, myocardial ischemia models were established by ranine vein of hypophysin in other four groups. The changes of lactate dehydrogenase,α-Hydroxybutyrate Dehydrogenase, creatine kinase, creatine kinase MB and ECG were recorded in each groups.

正常组和模型组予0.9%氯化钠注射液，复方丹参滴丸对照组予0.75%复方丹参滴丸水溶液，心痛治滴丸高剂量组、心痛治滴丸低剂量组分别给予3.6%、1.8%的心痛治滴丸水溶液，各组均10 mL/kg，每日1次灌胃。7日后除正常组外，其余4组均采用垂体后叶素0.5 U/kg舌下静脉注射制备大鼠急性心肌缺血模型，并检测各组乳酸脱氢酶、α-羟丁酸酶、磷酸肌酸激酶及磷酸肌酸激酶同工酶和心电图的改变。

Methods: 40 cases received the defibrase treatment. The initial dose of defibrase basis on plasma FIB level, the rechallenge time and dose are regulated according to the plasma FIB level , keeping the plasma FIB within 0.5～1.3g/L for one week.

对40例脑梗塞患者使用降纤酶治疗，治疗组给药方法：首次给药根据血浆FIB水平调整给药剂量，再次给药根据血浆FIB 水平调整降纤酶的使用剂量及使用时间。

Methods Dose measurement system(Diamentor K1)equipped with DSA machine(Angiostar-Plus,Seimens,Gemany),analyzed dose-aera-production(cGycm2)and entering doseof 432 patient having received interventional vascular radiology for diagnosis and treatment regressively.

方法采用Angiostar-Plus型DSA机随机配置的剂量测量系统(Diamentor K1)，回顾性分析432例经血管途径介入诊治的面积剂量乘积(DAP，cGycm2)和入射剂量。

Results EROD activities in liver of wild crucian from Zhangtan, Jiangjunyan, Fuyang and Wenyan (23.51±4.17, 16.79±7.39, 18.74±5.16, 18.65±8.86 nmol/) were significantly higher than that of Jiekou (7.84±2.42 nmol/g promin), and no difference was observed between the other sites and Jiekou. Three dose groups (0.25, 0.50, 1.00L/dish water sample extracts) were used in Ames test. Reversional mutation rate of TA98 colony exposed to extracts from Zhangtan was 2.21, 3.39, 6.95 without S9, and 2.70, 4.07, 6.23 with S9, respectively. The revesional mutation of TA100 colony was 2.55, 2.81, 5.36 without S9, and 1.73, 2.86, 4.14 with S9, respectively. Reversional mutation rate of TA98 colony exposed to 1.00L/dish extracts from Jiangjunyan with S9 was 2.22, and there was a dose-response relationship in reversional colony count. Ames tests of the other extracts were negative.

结果 樟潭、将军岩、富阳、闻堰点位野生鲫鱼肝EROD酶活性分别为(23.51±4.17)，(16.79±7.39)，(18.74±5.16)，(18.65±8.86)nmol/，明显高于街口[(7.84±2.42)nmol/]，其他点位与对照比较差异无统计学意义；樟潭水样浓集物在浓度为0.25，0.50，1.00 L/皿时在不加与加S9条件下，TA98回变菌落突变率MR值分别为2.21，3.39，6.95，2.70，4.07，6.23；TA100回变菌落MR值分别为2.55，2.81，5.36，1.73，2.86，4.14；Ames试验结果为明显阳性；将军岩水样浓集物在浓度为1.00 L/皿且加S9条件下TA98MR值为2.22，且在浓度为0.25，0.50，1.00 L/皿加S9条件下TA98回变菌落数呈剂量－反应关系，MR值分别为0.88，1.98，2.22；Ames试验结果为弱阳性；其他点位均为阴性。

Methods: Liver injure rat models were made by alcohol, the high-dose and low-dose ZhiGanQing Capsule were continuously watered by for 8 weeks, the contents of AST、ALT and TG were detected separatedly, and the hepatic pathology was observed too.

采用白酒复制大鼠肝损伤模型，脂肝清胶囊按高、低剂量灌胃，连续8周，测定血清天冬氨酸转氨酶、丙氨酸转氨酶及甘油三酯的含量，并观察肝脏的病理组织学改变。

The HIRFL (heavy ion research facility in Lanzhou)will be used as the injector. For the shielding design of CSR, the secondary neutrons due to the ion beam loss,their spectra and angular distributions were estimated based on the experimental results. The dose equivalent outside the shielding surface and in the surrounding environment and the neutron skyshine dose equivalent were also estimated in this study.

为了CSR的屏蔽设计，本文利用现有的实验数据计算了由于束流损失产生的中子及其能谱、角分布，同时也估算了屏蔽体外表面的中子剂量、环境中子剂量及天空返照中子剂量。

Under inverted microscope, stereognosis of neurons died down, there were blank bulb in the neurons, dark particle were seen in the neuritis; the result of MTT test showed that the survival rate of neurons was obviously decreased. Res 40μmol/L increased the survival rate of neurons. Aβ(subscript 25~35) dose-dependently increased the level of MDA, decreased the level of GSH. Res dose-dependently increased the level of GSH, decreased the level of MDA.

结果：Aβ(下标 25~35)在终浓度为2μmol/L时神经元形态有明显的变化，细胞立体感减弱，胞体内空泡形成，细胞突起内可见黑色颗粒状物；细胞的存活能力明显下降，与对照组相比较有显著性差异(P.05)；Res在终浓度40μmol/L时，能明显提高细胞的存活能力。Aβ(下标 25~35)可以明显升高细胞培养上清液中MDA含量，降低GSH的含量；Res可使细胞培养上清液中MDA含量下降，GSH含量增加。

Intravenous medium and high erythromycin and azithromycin dose had obvious exciting effect on spontaneous afferent nerve discharge (erythromycin: 8.34 ± 0.37, 8.54 ± 0.26 vs 7.78 ± 0.23, 7.84 ± 8.27; azithromycin: 8.57 ± 0.43, 8.28 ± 0.38 vs 7.74 ± 0.21, 7.86 ± 0.30) and gastric distention-induced afferent nerve discharge of subdiaphragmatic vagus nerve (erythromycin: 8.54 ± 0.34, 8.61 ± 0.20 vs 8.13 ± 0.36, 8.19 ± 0.21; azithromycin: 8.54 ± 0.30, 8.42 ± 0.21 vs 8.24 ± 0.22, 8.22 ± 0.19), which was statistically significant compared with the control and low dose groups.

结果： 静脉注射小剂量红霉素和阿齐霉素自发放电和对扩胃诱发放电均无显著变化， 20 min后中、大剂量红霉素和阿齐霉素注药后自发放电(红霉素： 8.34±0.37， 8.54±0.26 vs 7.78±0.23， 7.84±8.27；阿齐霉素： 8.57±0.43， 8.28±0.38 vs 7.74±0.21， 7.86±0.30)和对扩胃诱发放电均增强(红霉素： 8.54±0.34， 8.61±0.20 vs 8.13±0.36， 8.19±0.21；阿齐霉素： 8.54±0.30， 8.42±0.21 vs 8.24±0.22， 8.22±0.19)与相应的对照组和小剂量组间差异有统计学意义。

But Severus escaped the hands of those that Julianus had sent to murder him and sent a letter to the praetorian guard, giving them the signal either to desert Julianus or to kill him.

赛维鲁总算逃过了尤利阿努斯派来的杀手，并写了一封信给罗马的禁卫军，向他们发出信号，要么抛弃尤利阿努斯，要么干掉他。他们立即服从了。

This text is in terms of this of " human nature ", it is under the influence of western literature human nature thought to probe into, awakening in human nature of novel works and all sorts of limitations that affectionate The school of Mandarin Duck and butterfly.

本文便是从"人性"这一角度，探讨在西方文学人性思想的影响下，清末民初鸳鸯蝴蝶派的言情、哀情小说作品在人性方面的觉醒与种种局限。