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The effects and mechanism of GABAergic neurons, NOergic neurons, opioid peptide and cyclic adenosine monophosphate in the nucleus reticularis thalami on sleep-wakefulness cycle of rats and the effects and mechanism of the 5-HTergic nerve fibers project from the nucleus raphes dorsalis to RT on sleep-wakefulness cycle of rats were investigated with the methods of brain stereotaxic, nucleus spile, microinjection and polysomngraphy.1. The effects of GABAergic neurons in RT on sleep-wakefulness cycle of rats1.1 Microinjection of 3-mercaptopropionic acid (3-MP, a kind of glutamate decarboxylase inhibitor) into RT. On the day of microinjection, sleep only decreased a litter. On the second day, sleep marked decreased and wakefulness marked increased. On the third and fourth day, sleep and wakefulness stages resumed to normal.1.2 Microinjection of gamma-amino butyric acid (GABA 1.0μg) into RT enhanced sleep and reduced wakefulness compared with control; while microinjection of L-glutamate (L-Glu, 0.2μg) decreased sleep and increased wakefulness; microinjection of bicuculline (BIC, 1.0μg), a GABAA receptor antagonist, enhanced wakefulness and reduced sleep; microinjection of baclofen (BAC, 1.0μg), GABAB receptor agonist, had the same effects as GABA.2. The effects of NOergic neurons in RT on sleep-wakefulness cycle of rats2.1 Microinjection of L-arginine (L-Arg, 0.5μg) into RT decreased sleep compared with control, but there were on statistaical difference between L-Arg group and control; while microinjection of sodium nitroprusside (SNP, 0.2μg), a NO donor into RT, sleep marked decreased and wakefulness marked increased. Microinjection of nitric oxide synthase inhibitor, N-nitro-L-arginine (L-NNA, 2.0μg) into RT enhanced sleep and reduced wakefulness.2.2 After simultaneous microinjection of L-NNA (2.0μg) and SNP (0.2μg) into RT, SNP abolished the sleep-promoting effect of L-NNA compared with L-NNA group; after simultaneous microinjection of L-NNA (2.0μg) and L-Arg(0.5μg) into RT, we found that L-NNA could not blocked the wakefulness-promoting effect of L-Arg.3. The effects of opioid peptide in RT on sleep-wakefulness cycle of rats3.1 Microinjection of morphine sulfate (MOR, 1.0μg) into RT increased wakefulness and decreased sleep compared with control; while microinjection of naloxone hydrochloride (NAL, 1.0μg), the antagonist of opiate receptors, into RT, enhanced sleep and reduced wakefulness.3.2 After simultaneous microinjection of MOR (1.0μg) and NAL (1.0μg) into RT, the wakefulness-promoting effect of MOR and the sleep-promoting effect of NAL were not observed compared with control.4. The effects of cAMP in RT on sleep-wakefulness cycle of rats Microinjection of cAMP (1.0μg) into RT increased sleep and decreased wakefulness compared with control; microinjection of methylene blue (MB,1.0μg) into RT enhanced sleep and reduced wakefulness compared with control.5. The effects of the 5-HTergic nerve fibers project from DRN to RT on sleep-wakefulness cycle of rats5.1 When L-Glu (0.2μg) was microinjected into DRN and normal sodium (NS,1.0μg) was microinjected into bilateral RT. We found that sleep was decreased and wakefulness was increased compared with control; when L-Glu (0.2μg) was microinjected into DRN and methysergide (MS,1.0μg), a non-selective 5-HT antagonist, was microinjected into bilateral RT, We found that sleep was enhanced and wakefulness was reduced compared with L-Glu group.5.2 When p-chlorophenylalanine (PCPA, 10μg) was microinjected into DRN and NS (1.0μg) was microinjected into bilateral RT, We found that sleep was increased and wakefulness was decreased compared with control; microinjection of 5-hydroxytryptaphan (5-HTP, 1.0μg), which can convert to 5-HT by the enzyme tryptophane hydroxylase and enhance 5-HT into bilateral RT, could block the effect of microinjection of PCPA into DRN on sleep-wakefulness cycle.

本研究采用脑立体定位、核团插管、微量注射、多导睡眠描记等方法,研究丘脑网状核(nucleus reticularis thalami,RT)中γ-氨基丁酸(gamma-amino butyric acid ,GABA)能神经元、一氧化氮(nitrogen monoxidum,NO)能神经元、阿片肽类神经递质、环一磷酸腺苷(cyclic adenosine monophosphate,cAMP)及中缝背核(nucleus raphes dorsalis,DRN)至RT的5-羟色胺(5-hydroxytryptamine,5-HT)能神经纤维投射对大鼠睡眠-觉醒周期的影响及其作用机制。1 RT内GABA能神经元对大鼠睡眠-觉醒周期的影响1.1大鼠RT内微量注射GABA合成关键酶抑制剂3-巯基丙酸(3-MP,5μg),注射当天睡眠时间略有减少,第二日睡眠时间显著减少,觉醒时间明显增多,第三、四日睡眠和觉醒时间逐渐恢复至正常。1.2大鼠RT内微量注射GABA受体激动剂GABA( 1.0μg)后,与生理盐水组比较,睡眠时间增加,觉醒时间减少;而RT内微量注射L-谷氨酸(glutamic acid, L-Glu, 0.2μg)后,睡眠时间减少,觉醒时间增加;RT内微量注射GABAA受体阻断剂荷包牡丹碱(bicuculline,BIC,1.0μg)后,睡眠时间减少,觉醒时间增加;RT内微量注射GABAB受体激动剂氯苯氨丁酸(baclofen,BAC,1.0μg)后,产生了与GABA相似的促睡眠效果。2 RT内NO能神经元对大鼠睡眠-觉醒周期的影响2.1大鼠RT内微量注射NO的前体L-精氨酸(L-Arg,0.5μg)后,与生理盐水组对比,睡眠时间略有减少,但无显著性意义;而RT内微量注射NO的供体硝普钠(Sodium Nitroprusside,SNP,0.2μg)后可明显增加觉醒时间,缩短睡眠时间;微量注射一氧化氮合酶抑制剂L-硝基精氨酸(L-arginine,L-NNA,2.0μg)后,引起睡眠时间增多,觉醒时间减少。2.2大鼠RT内同时微量注射L-NNA(2.0μg)和SNP(0.2μg)后与L-NNA组比较发现SNP逆转了L-NNA的促睡眠作用;RT内同时微量注射L-NNA(2.0μg)和L-Arg(0.5μg)后,与L-NNA(2.0μg)组比较发现L-Arg可以增加觉醒而缩短睡眠,其促觉醒作用未能被NOS的抑制剂L-NNA所逆转。3 RT内阿片肽对大鼠睡眠-觉醒周期的影响3.1大鼠RT内微量注射硫酸吗啡(morphine sulfate,MOR,1.0μg)后与生理盐水组对比,睡眠时间减少而觉醒时间增加; RT内微量注射阿片肽受体拮抗剂盐酸纳洛酮(naloxone hydrochloride,NAL,1.0μg)后与生理盐水组比较,睡眠时间增加而觉醒时间减少。3.2大鼠RT内同时微量注射MOR(1.0μg)和NAL(1.0μg)后,与生理盐水组对比,原有的MOR促觉醒效果和NAL的促睡眠效果都没有表现。4 RT内环一磷酸腺苷信使对大鼠睡眠-觉醒周期的影响大鼠RT内微量注射cAMP(1.0μg)后与NS(1.0μg)组比较,睡眠时间增多而觉醒时间减少;RT内微量注射亚甲蓝(methylene blue,MB,1.0μg)后,与NS组比较,睡眠时间增多而觉醒时间减少。5中缝背核投射到丘脑网状核的5-羟色胺能神经纤维对大鼠睡眠-觉醒周期的影响5.1大鼠DRN内微量注射L-Glu(0.2μg),同时在双侧RT内微量注射NS (1.0μg)后,与对照组(DRN和双侧RT注射NS, 0.2μg)比较,睡眠时间减少,觉醒时间增多;大鼠DRN内微量注射L-Glu(0.2μg),同时在双侧RT内微量注射二甲基麦角新碱(methysergide, MS, 1.0μg )后,与对照组(DRN注射L-Glu 0.2μg,双侧RT注射NS 1.0μg)比较,睡眠时间增多,觉醒时间减少。5.2大鼠DRN内微量注射对氯苯丙氨酸(p-chlorophenylalanine,PCPA,10μg),同时在双侧RT内微量注射NS (1.0μg)后,与对照组(DRN和双侧RT注射NS, 1.0μg)比较,睡眠时间增多,觉醒时间减少;大鼠DRN内微量注射PCPA(10μg),产生睡眠增多效应后,在双侧RT内微量注射5-羟色胺酸(5-hydroxytryptaphan , 5-HTP, 1.0μg )后,与对照组(DRN注射PCPA 10μg,双侧RT注射NS 1.0μg)比较,睡眠时间减少,觉醒时间增多。

Divides according to the season, may divide into spring the radish and the fall radish; May divide into the large, medium and small three types according to the root size; Divides according to radish's color may divide into the turnip, the blue radish and the carrot.

按季节来分,可分为春萝卜和秋萝卜;按根的大小可分为大、中、小三类型;按萝卜的颜色来分又可分为白萝卜、青萝卜和红萝卜。

Feature of principal lines spatial distribution: detect the principal lines through edge detecting technology, and then divide the image of palmprint into blocks with same dimension, compute the mean and variance as feature; Feature of palmprint direction: divide the image into sub-images; compute the max angle of projection and coordinate of each sub-image, which stand for the direction and location of the line on the palm; Feature of moment invariants: compute the moment invariants of each sub-image and the whole image as feature.

掌纹主线空间分布特征:利用边缘检测技术检测出掌纹的主线,将图像分割成相同大小互不重叠的子图,提取每一个子图的均值和方差作为特征;掌纹线方向特征:将图像分成不重叠的子图,利用Radon变换求出每一个子图的最大投影角度和坐标,也就是子图内掌纹线的方向和位置,构造特征向量;掌纹不变矩特征:提取图像整体和分割后的子图的不变矩作为特征。

Turn dough out onto a lightly floured surface and divide it into half, each about 430 grams. Divide into thirds.

翻出面团,放到洒了少许面粉的台面上,用手排挤出面团的气体,匀分成2份,每份大约430克左右。

Based on the "Structural Holes" theory and the concept of "Bridge",combined with the characteristics of the sharing, divide the "Bridge" into five types. Discuss the role of the five types in sharing; Based on the results of the UCINET analysis, express the coordination role of coordinator, and give a optimization way of the inside network; Divide the broker into two types, and make a description of the two types' function in details; Integrate the discussion of gate keeper and representative, and descript the different function of them on the same system; Descript the function of the Simmel model,and illustrate the bad effect of the model and give measures to avoid that.

在简述"结构洞"理论和"桥"的概念的基础上,结合科技资源共享的特点,把"桥"划分为5种类型;对不同类型"桥"在共享中的作用进行论述;基于UCINET分析结果说明协调者的协调作用,并提出内部人际网络优化方法;对中介者进行再次分类,并详述两种模式在科技资源共享中的功能实现;将守门人与发言人综合论述,描述在同一个体系下实现两者不同作用;对齐美尔连带的作用进行论述,对其可能产生的负面影响进行说明并给出相应的避免措施。

Solves this symptom method to divide into the surgery and the non-surgery treats, the non-surgery treats for example the physical property treatment and the pharmacological treatment, the effect is not often good, the surgery treats may divide into the traditional surgery and micro creates the surgery two kinds, the traditional surgery method is in the lumbar vertebra fusion the pexia, although this method excised has created the lumbar vertebra narrow yellow ligament and the small surface joint, but the surgery time was long, the wound was big as well as although the lumbar vertebra fusion and fixed has removed the pathological change stage abnormal movement, but the neighbor stage's abnormal movement increased, between the awl in plate's pressure elevated obviously, the small articular process exceptionally drew back changes with the fixed stage bone quantityThe loss, causes the fixed stage vertical motion stage to draw back changes ASD[1], but new micro creates the surgery is opens a small wound in the back, and implants the interspinal to open, then solution lumbar vertebra narrow sickness question.

解决此种症状的方法分为手术及非手术治疗,非手术治疗例如物理性治疗和药物治疗,往往效果不佳,手术治疗又可分为传统手术和微创手术二种,传统手术方法就是腰椎融合内固定术,虽然此种方法切除了造成腰椎狭窄的黄韧带和小面关节,但手术时间长,伤口大以及腰椎的融合和固定虽去除了病变节段的异常活动,但邻近节段的异常活动增加,锥间盘内的压力明显升高,小关节突的异常退变和固定节段的骨量丢失,导致固定节段上下运动节段的退变ASD[1],而新型的微创手术是在背部开一个小伤口,并植入棘突间撑开器,进而解决腰椎狭窄症的问题。

To in boat letter this kinds of situation, not divide stage course project and for setting up on the each period of stage there aren't thought , stage of control goal, this text has proposed the control goal model of the quality of stage of course of development based on milestone innovativly, model this divide course that information system develop into feasibility analyse , encode , integrate , is it wait for 9 stages to test, and has confirmed the control goal of quality for each stage , has set up two milestones of quality control , navigate letter course stage that information system develop row , is it have achievement may be examined each period of stage to make, a quality goal is controlled , avoid developing the transparency of course and quality control defect not high of visuality like this.

针对中航信的这种情况,受工程项目对过程进行阶段划分并为每个阶段设立阶段控制目标的思想启发,本文创新性地提出了基于里程碑的开发过程阶段质量控制目标模型,该模型将信息系统开发的过程划分为可行性分析、编码、集成、测试等9个阶段,并为每个阶段确定了质量控制目标,设立了两个质量管理的里程碑,将中航信信息系统开发的过程阶段划,使每个阶段都有成果可以检验,都有质量目标进行控制,这样就避免了开发过程透明度和可视性不高的质量管理缺陷。

It abandon the traditional measure that divide the development course of the scientific and technological park according to the time, and redistrict their development courses according to the logic route that the park grew up, then divide development course into three stages: embryonic stage, it introduce domestic and international agricultural new and high technology , advanced equipment directly, engaged in running an enterprise on a commercial way, use the new and high technology to carry on precise, deep processing or storing and keeping fresh to the high-quality agricultural and animal products, do not have cooperation with local peasant basically; the stage of growing up, the park brings along local peasants production, does not confine to the production of the industrial base in the park again, a kind of nonstandard cooperative form has appeared between peasant and park; at ripe stage, the park sets up the training center of agricultural science and technology, carry on the professional technical training to the industrial base and peripheral peasant, spread through three kinds of diffusion effects, such as radiation, the grade

摒弃了按时间划分科技园区发展历程的传统作法,按照园区成长的逻辑路线对其发展历程进行了重新划分,将发展历程分为三个阶段:萌芽阶段,园区内直接引进国内外农业高新技术、先进设备,从事企业化生产,运用高新技术对优质农畜产品进行精、深加工或储藏保鲜,与当地农户基本上没有合作关系;成长阶段,园区带动当地农产生产,不再局限于园区內产业基地的生产,农产与园区之间出现了一种不规范的合作形式;成熟阶段,园区建立农业科技培训中心,对产业基地及周边农产进行专业技术培训,通过辐射扩散、等级扩散、跳跃扩散三种扩散效应,把经济动力和创新成果传导给周围地区,园区进入规范化管理阶段。

Meditation Alone/ firefly译 The Moon Is Mine The moon is mine And the sundries I home mail It's thin, cool and dark Like me under an unlucky star Who stay out straying, with a sadly sorrowful look When facing it You should feel esteem--in my opinion Also you could Weep when looking at it, and Be put in a tight spot, or Behold a man in it coming out Lay Open the Loneliness Lay open the loneliness, perhaps There be no loneliness Under the alone lamp, in the empty room The whole world's dyed orange with rays Everything represents nothing As someone been far away The deserted heart still misses Only lonely is still lonely Wine for one, when wine round three times for one Think of the drip drops, the fallen leaves, and Some time, some seasons, some persons, some Sundries when warm Like I lay open the loneliness Then nothing to keep lonely The Tree All the leaves in this tree fall Its loneliness falls into a face It's limpid and bright Where the sun shines There are blares of colored glaze Exclaim occasionally, or profoundly Stride one's line of sight, such height and weald Straying there --Why there is no wild Divide the Rain Drips Divide the dense rain drip Then you may see decaying scene-- A man in the sun walking with vigorous strides In the shallow puddle Immerges half his nose, spraying Continuous ripples It's simply a groundless guess at daytime Or rather a dream, yet that's it And that I see Sun's weak, and see The sun and water turns to be blank in the air Nov.

16th, 2007 原诗:《独想》《那些月光是我的》那些月光是我的是我寄给家里的物什它薄薄的,凉凉的,暗暗的就像我的薄命流浪在外,神情悲悯你们面对它应该感到高贵——这是我的想法你们也可以看着它流泪,看着它一筹莫展,或者看着一个人从里面走出来《把孤独摊开》把孤独摊开,或许就没有孤独了在孤灯下,空屋里万物都染着桔色的光万事都不代表什么就像远去了一个人心中空荡荡的,却总有惦念但孤独还是孤独的一个人的酒,一个人酒过三巡想想窗檐的滴水,想想落叶,想想一些时间,一些季节,一些人物,一些那时感到有温度的物什就如同把孤独摊开了没什么可继续孤独的《这棵树》这棵树落光了叶子它的孤独就成了一张脸它清澈与明亮太阳光照的地方,全然是时空中一簇琉璃的光泽偶尔让人惊叹,偶尔骨感地跨入人的视线,那样的旷野和高度停留在那里——为什么没有荒芜《把雨点分开》把稠密的雨点分开就可以看到颓废的景观——一个刚在太阳下健步如飞的男人在浅水坑中浸入了一半的鼻子,喷着连续不断的涟漪这只是我白日的一个臆念有点梦,但就是这样我才看到了阳光的软弱,看到了阳光和雨水原来就是一场空中之茫

There are two traditional ways of dividing the American Anthropology,oneis to divide it according to the line of substantivists and formalists,anotherway is to divide it into four categories:formalist,subtantivist,neo-maxistand economic ethnohistorian.

笔者认为,如果根据&四个基本一致&(即理论观点基本一致、研究方法上基本一致、政策主张、利益诉求上都基本一致)原则划分的话,则美国经济人类学应可划分为:以赫兹克维茨、斯内德尔为代表的形式主义流派,以波朗尼、多尔顿为代表的实在主义流派,以哈特、沃尔夫等为代表的新马克思主义流派和以威尔克等为代表的新广义派。

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相关中文对照歌词
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推荐网络例句

He became prime minister in 1997 and won international acclaim for his role in the Northern Ireland peace process.

他在1997年成为总理,并且因为在北爱尔兰的和平进程中发挥的作用受到国际社会的赞许。

Mixed Page Sorting Method Using the cuttable user model, this thesis proposes a mixed page sorting method by using cutted user model in server-side and complete user model in client-side.

隐私分级利用的混合式页面排序方法针对个性化搜索中搜索结果排序的问题,本文利用隐私可控开放的用户偏好模型,提出一个在客户端和服务器端分步进行的隐私分级利用的混合式页面排序方法。

You can laud them for speaking their minds, or you can criticize them for their big mouth, but you cannot deny that these retorts, rebuttals and asides add much needed color to an otherwise drab portrait of Chinese officialdom.

你可以赞扬他们直抒胸臆,也可以骂他们的大丑嘴巴,但你不能否认,这些反驳和旁白为中国官场众生相添加了新的色彩。