查询词典 depressing clouds

HXJ has inhibitory effects on alveolitis and pulmonary fibrosis in this model possibly by depressing NF-κB activity.

以上均表明化纤胶囊在抑制NF-κB表达方面较强的松好。

When there was no thrombin, aptamer probes could hybridize with molecular beacons in the highest degree, generating the largest fluorescence signal; when thrombin was introduced, the hybridization of molecular beacons and probes was depressed, and the depressing degree was associable with the concentration of thrombin.

没有凝血酶存在时，识体探针可以和分子信标最大程度地杂交，使得分子信标的荧光信号上升；当存在凝血酶时，与凝血酶孵育结合后的识体探针再与分子信标作用，分子信标被打开的程度有所降低，并且打开程度的降低程度与凝血酶浓度有关。

The study showed the recombinant wt/mCREG protein depressed the VSMC proliferation depending on dose and the optimal concentration was 400nM;2biologic function of CREG protein and the membrance receptor mechanism:①effect on VSMC migration: the wound healing experiment showed the OB2 cells migration was slower significantly after added wt/mCREG(400Nm) in supernatant. The HITASY cells migration were very slowly and no remarkable change. The gelatinase digestion and Western blot analysis showed the matrix metalloproteinase was decreased and TIMPs was increased;②effect on differentiation: after added wt/mCREG(400nM), the expression of myocardin, SMα-actin, MHC and caldesmin were increased and that of LM-1 and FN were decreased in OB2 cells. These effects were more significant when adding wtCREG.;③effect on VSMC proliferation: Cell cycle assay and BrDU stain showed: after added the wtCREG and mCREG protein, the ratio of cell in G0/G1 phase increased to 0.5773 and 0.5572 from 0.5308 respectively in OB2 group, which increased to 0.7369 and 0.7034 respectively from 0.6297 in HITASY group;3Role of M6P/IGF2R in CREG biologic function:①ELISA and co-immunoprecipitation showed the wt/mCREG binding to M6P/IGF2R directly.②antibody blocking test: when the anti-IGF2R was added to medium at the same time with wt/mCREG at different concentration(2μg/mL、4μg/mL、8μg/mL),the effects of CREG protein which depressing proliferation, migration, secretion and promoting differentiation were blocked, which had the positive correlation to the concentration of added anti body. The studies showed two combinant CREG promoted VSMC switch to differentiation phaenotype, at the same time, depress VSMC proliferation, migration and secreting extracellular matrix.

上述实验结果证实：两种重组CREG蛋白对VSMC增殖均有剂量依赖性的抑制作用，并且相同浓度的糖基化的CREG蛋白对细胞增殖的抑制效应更为显著，最佳效应浓度为400nM；2两种重组CREG蛋白添加后对HITASY和OB2细胞生物学行为的影响：①CREG蛋白对VSMC迁移的影响：刮伤实验发现，加入最佳效应浓度的wtCREG和mCREG蛋白24h后，OB2组迁移能力下降，HITASY组无明显变化；细胞外基质金属蛋白酶-2，9(Matrix metallo-proteinase 2，9，MMP2 ，9)明胶酶电泳检测和Western blot检测结果证实，两种CREG蛋白均可以使OB2细胞合成细胞外基质MMP2，9减少，而组织金属蛋白酶抑制物(Tissue Inhibitors of Metalloproteinases，TIMPs)增加；②CREG蛋白对VSMC分化的影响：加入400nM的wtCREG和mCREG蛋白12h后，OB2细胞myocardin、SMα-actin、MHC、caldesmin表达增加，LM-1、FN表达减少；③流式细胞仪分析细胞周期和BrDU染色分析证实，加入400nM的wtCREG和mCREG蛋白后，OB2组G0/G1期细胞由0.5308分别增加至0.5773和0.5572，HITASY组G0/G1期细胞由0.6297分别增加至0.7369和0.7034；3M6P/IGF2R在重组CREG蛋白的生物学功能中的调控作用：①免疫共沉淀和免疫荧光双染色分析结果显示，CREG蛋白与M6P/IGF2R存在直接结合；②应用抗体阻断实验：将不同浓度的anti- M6P/IGF2R(2、4、8μg /mL)与两种CREG蛋白同时加入培养液中，CREG蛋白抑制VSMC增值、迁移和合成细胞外基质、促进分化的效应减弱，而且与加入anti- M6P/IGF2R浓度正相关。

The instances are few indeed in which the operation of the machine guns appears to be the decisive factor in retaining a position, or in depressing the counterfire which is deterring the attack.

距离有限，使机枪不能发挥防御点和在交火中阻止敌人进攻的关键作用。怎么会这样？

The instances are few indeed in which the operation of the machine guns appears to be the decisive factor in retaining a position, or in depressing the counterfire which is deterring the attack.

怎么会这样？

The actuator assembly additionally includes a feature of providing a raised region along an outer surface of the positionable member which guards against accidental or unintentional depressing of the depressible member.

致动器组件又包括沿着可定位元件的外表面提供一个凸起区域的特征，其保证防止意外或无意地压下可压下元件。

objective the effect of injecting flurbiprofen about depressing the stress reaction of gerontal patient under general anaesthesia after operation completion was studied.

目的：探讨氟比洛芬酯对老年患者全麻术后气管拔管期间应激反应的影响。

It seems that there are much more un-natural likes in my heart in these ten days. Staring at the sky with a little vacant and inexplainable and depressed mood, suddenly the depressing sky rains, I am so startled by it, doesn't it mean that this is the "tear-likes"?

好像十几天的非正常生活让我的心里多了许许多多的非正常的喜欢，以有点空洞的无法解释的深沉心情望着天空，深沉天空忽然下起雨来了，我大惊，难道这是泪的喜欢？

Once the mount is attached, the light can be easily slid onto the mount, where it locks in place; depressing a small lever slides it right off, so the Helmet Light can be quickly removed for servicing or transport onto its optional Z71 carry clip, which attaches to any MOLLE or ALICE vest.

抬起小杠并且滑动，它就能轻易的松脱。所以这款头盔灯能够很快的拆卸，适合于各种环境下的使用需要，也能够装在采用MOLLE系统和ALICE系统的背心上

Furthermore, we discussed and pointed out the exact distinction of the meanings of reactive current, irregular current, reactive power and irregular power, then we give them proper mathematic definition with uniformed conception respectively, we established new power system, which is helpful for people to understand about nonsinusoidal system and its energy conversion much more deeply and substantialy, especially to gain new ideas on depressing and eliminating harmonic waves, and some new design method for more satisfying correcting power function, and different kinds of compensation and eliminating harmonic wave systems.

本文分析了传统的正弦系统有关定义及其与非正弦系统的异同，指出了前者存在的缺点，结合所给特例，讨论并确定了时域中非正弦系统有功电流和有功功率的严格定义，阐明了畸变功率在非正弦系统能量转换过程中所起的作用，在上述基础上，进而讨论并严格区分子无功电流、畸变电流、无功功率、畸变功率等的含义，并利用变分法给出了与上述含义相一致的各个概念的严格的数学定义；提出了新的功率体系。

I want to be a big fish in a small pond.

我要做一条在小池塘里的大鱼。

While the software functioned well, we did not feel the same about their customer support!

虽然该软件运行良好，我们没有同样的感觉他们的客户支持！