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Conclusions1、E_2 may induce the apoptosis and Fas,FasL expressions of Jurkat cell,its effect positively related to the dose and treating time of E_2.2、There is intrinsic co-expression of ERαand ERβon Jurkat cell,which can be upregulated by E_2,positively related to E_2 doses.3、E_2 may act as an apoptosis inducer of Jurkat cell via ERβ.4、E_2 can promote the transcriptive activity of NF-κB in Jurkat cell.The increased NF-κB activity may lead to increased apoptosis of Jurkat cell.

结论1、E_2可增加Jurkat细胞的凋亡,并增加Fas、FasL的蛋白表达,且其作用与E_2的剂量和处理时间呈正相关。2、Jurkat细胞上存在ERα、ERβ的表达,且E_2可上调这两种受体的表达,E_2剂量越大,ER表达量越高。3、E_2可能通过ERβ发挥其促进Jurkat细胞凋亡的作用。4、E_2能增加Jurkat细胞中NF-κB的转录活性,Jurkat细胞中NF-κB活性增加有促进凋亡的作用。

Kangdai Ⅰ has protective function to the damaged neurons and astrocytes: Main results:(1) It has direct protective function to the damaged neurons. It can increase the activity and survival rate, decrease the mortality and the transudation rate of LDH in cultured medium and the strong positive cell count of NOS expression of injured neurons.(2) It has also directly protective function to the damaged astrocytes. It can increase the activity and survival rate and protein content in conditioned medium.(3) It can strengthen the ability of BDNF, GDNF, bFGF, HSP and IL-6expression in damaged astrocytes.(4) It can also strengthen obviously the expressions of NSE, bFGF-receptor and bc1-2, lower the expression of bax and caspase-3.(5) It can indirectly protect and restore the damaged neurons by astrocytes. Because the effect of ACMK (ACM interfered by Kangdai Ⅰ) is stronger than ACM+K (ACM associated with Kangdai Ⅰ).

抗呆Ⅰ号对受损的神经元和星形胶质细胞均具有保护作用:主要表现为:(1)对受损神经元具有直接的保护作用,可提高受损神经元的活性和存活率,降低细胞培养液LDH的漏出率、细胞死亡率和NOS染色强阳性细胞的表达量;(2)对受损的星形胶质细胞也有直接的保护作用,可提高其活性、存活率以及培养液蛋白质的含量;(3)能增强受损星形胶质细胞分泌BDNF、GDNF、bFGF、HSP和IL-6的能力;(4)可明显增强受损神经元对NSE、bFGF的受体和bc1-2的表达,降低受损神经元对bax和caspase-3的表达;(5)抗呆Ⅰ号可通过星形胶质细胞间接地保护和修复受损的神经元,因为在多数实验组中经抗呆Ⅰ号作用的ACM的作用远大于ACM与抗呆Ⅰ号联合应用的作用,统计学上具有显著性差异。

First, through monofactorial experiment, we studied the influences of pH, temperature and substrate concentration on acidic trehalase activity of baker's yeast. Then we designed an orthogonal experiment to detective the optimal condition of ascertaining acidic trehalase activity. The optimal conditions are: substrate concentration 1.6%, pH 4.0, temperature 30 and seed volume 0.02g/mL compressed yeast.

首先通过单因素实验研究了pH值、温度、底物浓度对面包酵母酸性海藻糖酶活性的影响,然后通过正交试验得出了酸性海藻糖酶活性测定的适宜条件:海藻糖浓度1.6%、温度30℃、pH 4.0、酵母菌泥接种量为0.02g/mL。

This dissertation provides that the financial behavior mechanism is a special economic running mechanism in terms of a complete organism with triadic reciprocal causation and interplay among financial behavior selection, subject and environment, which has the control and readjustment function to the financial activity and even the total social economic activity. Chapter One: Introduction. This chapter provides the research objects, research methods and the structure of this dissertation.

因而,深入剖析财务行为的本质,全面揭示财务行为主体、理财环境与财务行为选择的内在联系,对理性选择研究范式进行彻底革命,就成为当前财务行为理论以至整个财务理论研究所必须解决的根本问题之一。

No considerable effect was observed on the COX activity of P.falciparum treated with daphnetin-Fe complex. The tyrosyl free radical was tested to reflect the RNR activity of P.falciparum at various times by ESR.

结果 体外同步培养的恶性疟原虫经瑞香素(100 μmol/L)作用2、4、8和12 h后,COX活性分别被抑制了0、6%、73%和80%;在瑞香素浓度为0.1、1、100和1 000 μmol/L,作用6 h后,COX活性分别被抑制3%、31%、53%和84%;而瑞香素-Fe复合物对COX的影响几乎消失。

The results of bioassay indicated: 1 The new compound (compound 6) and other three compounds (compound 1, 2 and 5) showed strong anti-HIV activity (EC50.064μg/ml), compound 3 and 4 showed less activity (EC50=6.18μg/ml and 12.85μg/ml respectively); Compound 5 and 6 showed weak cytotoxicity, and compound 1-4 showed moderate cytotoxicity; 2 Compound 5 and 6 were activated to all the four tested microbial; Compound 1, 2 and 13 were activated to all the three tested bacterial, but were unactivated to the tested fungi, Penicillium avellaneumUC-4376; One of the test bacterial, Staphylococcus aurues, seemed to be sensitive to all the eleven triterpenoids.

新化合物(化合物6)和化合物1、2、5具有强烈的体外抗HIV活性,其EC50值均小于0.064μg/ml,化合物3和4也具有抗HIV活性,但活性相对较弱,EC50值分别为6.18μg/ml和12.85μg/ml;化合物1-6都具有一定的细胞毒性,且化合物5和6的细胞毒性明显弱于化合物1-4的。 2)新化合物(化合物6)和化合物5对所有四种试验菌都有一定的活性;化合物1 、2和13对三种细菌均有一定的活性,但对真菌橙色青霉UC-4367(Penicillium avellaneum UC-4376)无活性;金黄色葡萄球菌对所有11个三萜都较为敏感。

Versicolor suited to grow and produce laccases at pH value 3.5-5.7, and unbuffered media were able to get good laccase productivity though buffered media could get higher laccase activity. Metal ions Cu(superscript 2+) and Mn(superscript 2+) in the culture could remarkably increase the activity of laccases. The optimal concentration of Cu(superscript 2+) was 0.008-0.08mmol/L, and the optimal concentration of Mn(superscript 2+) was about 0.01mmol/L, when the culture contained 0.1mmol/L 2,5-dimethoxyaniline.

结果发现该菌种适宜在pH值3.5~5.7环境下生长并合成漆酶,培养基中添加缓冲液可以获得更高的酶活,但不加则有较高的酶产率;铜和锰可以显著提高漆酶活力,当以0.1mmol/L 2,5-二甲基苯胺为诱导剂时,培养基中宜含0.008~0.08mmol/L Cu(上标 2+),0.01mmol/L左右的Mn(上标 2+)。

Objective:The koji, production process and product index of North of Hunan unhusked rice wine and Middle Hunan rice wine were studied to give evidence for industrial production of unhusked rice wine; Methods: Glucoamylase activity, alcoholic fermentation activity, alcoholicity, all ester and the number of microbe were examined with ordinary ways; Results:The number of microbe and Rhiz.

目的:对湘北谷酒与湘中米酒酒曲、生产工艺以及成品酒指标进行比较,为谷酒的产业化生产提供依据;方法:采用常规方法测定、比较糖化力、酒化力、酒精度、总酯、微生物含量;结果:谷酒酒曲的微生物总数、根霉菌数糖化力与湘中米酒酒曲基本相同,但酵母数、酒化力略高于米酒酒曲;湘北谷酒的酒度、出酒率和总酯均高于湘中米酒,高级醇含量基本持平,感官指标优于湘中米酒;结论:谷酒较米酒的发酵工艺更合理,蒸馏方式更科学,产品质量更稳定;谷酒比米酒更适合大规模产业化。

Fluouricil is usually used as anticancer drug, its derivative, 5-fluoro-uracil-1- acetic acid has good biological activity. Its complexes were presented in literatures. However, the coordination modes of it are paradox in literatures. The single crystal structure was resolved to clarify the confusion. The result indicates the carboxylic group coordinates to zinc ion in unidentate, and the heteroatoms of pyrimidine ring are not involved in coordination. Antitumor activity against SMMC-7721 was also examined.

7.5-氟尿嘧啶是临床上广泛使用的抗癌药物,它的衍生物5-氟尿嘧啶-1-乙酸亦具有良好的生物活性,有关它的金属配合物亦有报道,但其结构指认相当混乱,为此研究了它与锌的配合物单晶结构,证明了5-氟尿嘧啶以单齿羧基与锌配位,而嘧啶环氮并未配位,也研究了它对SMMC-7721细胞株的抗肿瘤作用。

Even unplugging the TV so you have to find the cord and plug it in to use it will help you reduce the time spend in that activity since you can't as easily do the activity mindlessly.

如果你有期望、动机和能力,那么你完全可以停止做那些你认为是浪费时间和精力的事情。

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相关中文对照歌词
Activity As Phuctivity
Activity Grrrl
Activity Grrl
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What are your goals and strategies for growth?

你的成长目标和策略是什么?

And unto the angel of the church in Sardis write; These things saith he that hath the seven irits of God, and the seven star I know thy works, that thou hast a name that thou livest, and art dead.

3:1 你要写信给撒狄教会的使者,说,那有神的七灵和七星的,说,我知道你的行为,按名你是活的,其实是死的。

"It is a testament to making sure unemployment compensation is available, making sure we are looking out for people who have lost their jobs," she said.

"这是个实证,证明我们必须确保人们都可以得到失业补偿,确保那些失去工作的人们得到照顾。"