查询词典 R.D.

Result: Contrary to European and American people, I allele frequency of Han nationality is higher than that of D allele (P.05); II genotype frequency and DD genotype frequency are noticeably different from that of European and American people (P.01); No DD genotype appear in the excellent athletes, which is noticeably lower than that of control group and athlete group (P.05) and that of the excellent athletes reported in other countries; the frequency distribution of II genotype in Marathon is noticeably higher than that in 5km distance running(P.10); The changing of I allele Jl genotype IP ID genotype frequency indicates a stronger unary liner relation (r=0.9985) with the running distance lengthening(5ktru lOkrru Marathon).

结果显示：与欧美人群相反，汉族I等位基因频率高于D等位基因（P＜0.05）；汉族II型纯合子频率和DD型纯合子频率非常显著地区别于欧美人群（P＜0.01）；在优秀运动员中，DD型纯合子未出现一例，显著低于对照组和运动员（P＜0.05），也显著低于国外已报道的优秀运动员；马拉松项目II型频率分布显著高于5km（P＜0.10）；I等位基因、II基因型和ID基因型的频率变化伴随专项距离（5km、10km、马拉松）的增加呈现强相关的一元线性关系（r=0.9985）。

Results: Tyroserleutide can significantly increase the life span of H22 tumor-bearing mice by 50-70% in dosages of 20ug/kg/d-80ug/kg/d,specially the high dosage of 80ug/ml can significantly increase the life span by 69.24%; Tyroserleutide can inhibit the growth of transplanted hepatocellular tumor BEL-7402 in nude mice,the rate of tumor inhibition was25-50% in dosages of 40-320ug/ml ,the inhibition rate of 160ng/ml was 44.03%; Tyroserleutide could inhibit the growth of H22 and BEL-7402 tumor in a dose-dependent manner. Simultaneously, tumoricidal activity of tyroserleutide against BEL-7402 cell line in vitro was observed hinger when compared with the control group(P.05).The inhibition effect of 72hrs was higher than 24hrs,48hrs,96hrs.And specially the high dosage of 160ug/ml can significantly inhibit growth of tumor cell by 19.36%. Tyroserleutide can activated PEM and marked enhance cytotoxicity andphagocytosis functions in vitro and in vivo. The OD values of cytotoxicity were observed hinger when compared with the control group(P.05).The cytotoxicity of macrophages activated by tyroserleutide against BEL-7402 and B16-F10 was 35.58%,61.2% in vitro and21.39%,47.63% in vivo. The cytotoxicity rate of nude mice PEM was 32.86%,73.07% in vivo. Furthermore, tyroserleutide alone could stimulated the production of IL-1B TNF- a and NO by M . Tyroserleutide and LPS could synergistically activated M producing more cytotoxicity effectors. Conclusion: Tyroserleutide had inhibition functions against hepatoma carcinoma .Its possible mechanisms were related to the affect that Tyroserleutide could inhibit tumor cell directively and induce tumor cells apoptosis or death effectively.

结果：酪丝亮肽能显著延长腹水型肝癌H_(22)小鼠的生存时间，给药剂量为80μg／kg／d时疗效最显著，达到69.24％，在20μg／kg／d-80μg／kg／d剂量范围内生命延长率为50-70％，给药剂量与荷瘤鼠生存时间呈现一定量效关系；酪丝亮肽能显著抑制人肝癌BEL-7402移植瘤裸鼠的肿瘤生长，给药剂量为160μg／kg／d时疗效最显著，抑制率为44.03％，并且在40-320μg／kg／d剂量范围内抑制率为25-50％，给药剂量与肿瘤抑制率呈现一定量效关系；酪丝亮肽体外对人肝癌BEL-7402细胞生长有一定的抑制作用，在作用72hrs时各浓度酪丝亮肽对肿瘤细胞的抑制作用较24hrs、48hrs、96hrs明显，其中浓度为100μg／ml时抑制率达19.36％；酪丝亮肽体内外均能增强小鼠腹腔巨噬细胞对肿瘤细胞的杀伤：体外作用中巨噬细胞对BEL-7402、B16-F10的杀伤功能明显增强，与效应细胞对照组相比有显著性差异(P＜0.05)杀伤率分别达到35.58％、61.2％；体内作用中巨噬细胞对BEL-7402、B16-F10的杀伤功能明显增强，与生理盐水对照组相比有显著性差异(P 。05)，杀伤率分别达到21.39%、47.63%；裸鼠腹腔巨噬细胞经酪丝亮肤作用后对BEL一7402、B 16一F10杀伤功能明显增强，与生理盐水对照组相比有显著性差异(P.05)，最高杀伤率分别达到32.86%、73.07%；酪丝亮肤能增强单核巨噬细胞系统的吞噬功能，吞噬指数与生理盐水组比较有显著性差异(P.05)；酪丝亮肤体外作用能促进小鼠腹腔巨噬细胞分泌合成细胞毒效应分子IL一lp、TNF一Q和NO，与效应细胞对照组相比有显著性差异(P.05)；酪丝亮肤体内作用能促进小鼠腹腔巨噬细胞分泌合成细胞毒效应分子IL一lp、TNF一Q和NO，与生理盐水对照组相比有显著性差异(P.05)；酪丝亮肤能促进鼠巨噬细胞株R戌W264.7分泌合成IL一1p和NO，IL一1日、NO水平分别在酪丝亮肤作用24hrs、12hrs时达到高峰，酪丝亮肤单独应用能提高巨噬细胞的分泌合成功能，而且酪丝亮肤能与LPS协同作用刺激巨噬细胞的细胞毒效应分子分泌合成。

Objective To study the relationship of endangium proliferation and the expression of metalloproteinases and tissue inhibitors of metalloproteinases after angioplasty of iliac artery in rabbits to investigate the probable mechanism of composite Danshen pill in prevention and treatment of restenosisMethods 30 white male rabbits of Japan （the average body weight was 25～30 kg）were randomly divided into 3 groups:normal control group,model group (intima destroyed by balloon and given hypercholesterol diet),CDP group (intima destroyed by balloon and given hypercholesterol diet plus drug CDP 150 mg/d),10 ones each groupResults The results of iliac artery angiogram and the analysis of pathology:there were lumens stenosis,thinner intima,smaller intima area,in CDP group compared with those in model group,and ratio of intima and tunica media thickness and area among each group (P＜001)Immunohistochemistry analysis:the MMP2,MMP9,TIMP1,TIMP2 in model group significantly increased than those in control group (P＜001)The CDP group had lower MMP2 and MMP9 expression,higher TIMP1 and TIMP2 expression,and increased MMP2/TIMP1,MMP9/TIMP2 than model group (P＜001)The thickening of vascular neointima and stenosis degree of vascular lumen were relevant to MMP2 and MMP9 (r=0896,P＜001)Conclusions MMP and TIMP play the very important role in the restenosis process of arteryCDP could inhibit the thickness of vascular neointima after balloon injury,the probable mechanism of which may be inhibiting collagen formation,smooth muscle immigration and decreasing hyperplasia of intima by interfering expression of MMPs and TIMPs

目的 研究兔髂动脉成形术后血管内膜增生和基质金属蛋白酶及其抑制物表达之间的关系，探讨复方丹参滴丸预防再狭窄的可能机制。方法健康成年二级雄性日本大耳白兔30只，平均体重25～30 kg。随机分为3组：正常对照组10只，模型组10只（球囊内膜剥脱加高胆固醇饮食），治疗组10只（球囊内膜剥脱加高胆固醇饮食以及复方丹参滴丸150 mg/d）。结果兔髂动脉造影、血管病理图像分析检测结果：①复方丹参滴丸组较模型组血管造影示管腔直径狭窄、内膜厚度减少、内膜面积减少、内膜厚度和中膜厚度比、面积比，各组之间有显著性差异(P＜001)。②免疫组化分析：模型组MMP2、MMP9、TIMP1、TIMP2表达均高于对照组（P＜001）；复方丹参滴丸组MMP2、MMP9的表达低于模型组，而TIMP1、TIMP2的表达高于模型组；TIMP1/MMP2、TIMP2/MMP9明显增加，差异有显著性（P＜001）。③内膜的增生以及管腔的狭窄程度与MMP2、MMP9有很好的相关性(r=0896，P＜001)。结论 MMP和TIMP在再狭窄形成中起重要作用；复方丹参滴丸能够明显抑制血管损伤后的内膜增生，可能的机制是通过影响金属蛋白酶MMP2、MMP9及其抑制物TIMP1、TIMP2的表达从而抑制胶原的生成、平滑肌的迁移、增生，而减少内膜的增生。

Many critics refuse to assign any strata of Judges to the Hexateuchal fictions -- J, E, JH, P or R, and D, even though they postulate many and late sources for the book in its present state.

很多批评者拒绝指派任何阶层的法官向hexateuchal小说-J以来，英，法家，磷或R ，和D ，即使他们设许多后期来源为这本书在目前的状态。

Results Eleven compounds were obtained and identified as sarcodonin A, scabronine B, 3β-hydroxy-5α, 8a-epidioxyergosta-6, 22-dien,(22E, 24R)-ergosta-7, 22-diene-3β, 5α, 6β-triol,(22E, 24R)-ergosta-7, 22-diene-3β-ol, benzoic acid, 4-hydroxylben-zaldehyde, 4-monopropanoylbenzenediol, ethy1-β-D-glucopyranoside, thioacetic anhydride,(2S, 2'R, 3S, 4R)-2-(2-hydroxyoctadecanoylamino) docosane-1, 3, 4-triol.

结果共分离鉴定了11个化合物，分别是：sarcodonin A、scabronine B、3β羟－5α，5α-过氧麦角甾－6，22-二烯－3β-醇、(22E，24R)-麦角甾－7，22-二烯－3β，5α，6β三醇、(22E，24R)-麦角甾－7，22-二烯－3β-醇、苯甲酸、对羟基苯甲醛、对羟基苯甲酸乙酯、乙基－β-D-吡喃葡萄糖苷、硫代乙酸酐、（25，2'R，3S，4R）-2-（2-羟基－十八碳酰胺）二十二碳烷－l，3，4-三醇。

The biological activity of two immunologically similar recombinant grass carp growth hormone were compared with recombinant tuna Thunnus thynnus growth hormone, as well as an analog of LHRH(D—Ala~6, Pro~9—N—Etylamide—LHRH, LHRH—A).

本文对两种具有相似免疫活性的草鱼基因重组生长激素(r—gGH—Ⅰ、r—gGH—Ⅱ)的生物活性进行了初步研究，并把它们对草鱼鱼种生长的促进能力与金枪鱼基因重组生长激素的一种高效类似物LHRH—A(D—Ala~6，Pro~9—N—Etylamide—LHRH)进行了比较。

The inner reorganization energy and the exothermicity of the reaction are then determined. Closed shell HF SCF calculations have been carried out for the systems Tryptophy1-Tyrosine and Tyrosyl-Tryptophan for different values of R, and the Koopmans^,theorem is invoked to estimate the energy level splitting A.From the obtained A~m~i~n, the values of electron transfer matrix element V~D~A are determined to be 0.96kJ. mol^-^1 and 0.87kJ.mol^-^1 for Tryptophyl-Tyrosine and Tyrosyl- Tryptophan, respectively.

对色氨酰酪氨酸和酪氨酰色氨酸体系进行闭壳层HF自洽场计算，按Koopmans定理计算体系分子轨道分裂能值A，在R约为0处发现了A的极小值，从而获得色氨酰酪氨酸及酪氨酰色氨酸体系分子内电子转移的电子转移矩阵元V~D~A分别为0.96kJ.mol^-^1和0.87kJ.mol^-^1。

Faithfully sticking to the story of the NES game, Bionic Commando Rearmed tells the story of Nathan "R.A.D."

忠实地坚持 NES 游戏的故事，仿生 Commando Rearmed 讲述森&R.A.D。&

Uh Uh, uh, huh Yo, yo Drop your glasses, shake your asses Face screwed up like you having hot flashes Which one, pick one, this one, classic Red from blonde, yeah bitch Im drastic Why this, why that, lips stop askin Listen to me baby, relax and start passin Expressway, hair back, weavin through the traffic This one strong should be labeled as a hazard Some of yall niggas hot, sike Im gassin Clowns I spot em and I cant stop laughin Easy come, easy go, E-V gon be lastin Jealousy, let it go, results could be tragic Some of yall aint writin well, too concerned with fashion None of you aint gizell, cat walk and imagine Alotta yall Hollywood, drama, passed it Cut bitch, camera off, real shit, blast it And if I had to give you up Its only been a year Now I got my foot through the door And I aint goin nowhere It took awhile to get me in And Im gonna take my time Dont fight that good shit in your ear Now let me blow ya mind They wanna bank up, crank up, makes me dizzy Shank up, haters wanna come after me You aint a ganster, prankster, too much to eat Snakes in my path wanna smile up at me Now while you grittin your teeth Frustration baby you gotta breathe Take alot more that you to get rid of me You see I do what they cant do, I just do me Aint no stress when it comes to stage, get what you see Meet me in the lab, pen and pad, dont believe Huh, sixteens mine, create my own lines Love for my wordplay thats hard to find Sophomore, I aint scared, one of a kind All I do is contemplate ways to make your fans mine Eyes bloodshot, stressin, chills up your spine Huh, sick to your stomach wishin I wrote your lines And if I had to give you up Its only been a year Now I got my foot through the door And I aint goin nowhere It took awhile to get me in And Im gonna take my time Dont fight that good shit in your ear Now let me blow ya mind Let your bones crack Your back pop, I cant stop Excitement, glock shots from your stash box Fuck it, thugged out, I respect the cash route Locked down, blastin, sets while I mash out Yeah nigga, mash out, D-R-E Back track, think back, E-V-E Do you like that, you got to I know you Had you in a trance first glance from the floor too Dont believe Ill show you, take you with me Turn you on, pension gone, give you relief Put your trust in a bomb when you listen to me Dancin much, get it all?

Uh Uh ， uh，哼！ Yo， yo 降低你的眼镜，摇动你的驴脸振作起来像你有热的闪光哪一个，精选一，这一个，古典作品红色的从金发碧眼的女人，是的母狗 Im 激烈的为什么这，为什么那，唇停止 askin 听我的话宝贝，放松而且开始 passin 高速道路，头发背面，透过交通的 weavin 这一个强壮的应该被贴标签为危险一些 yall niggas 热的， sike Im gassin 我弄脏 em 的小丑和我讲黑话停止 laughin 易得易失，电子 V gon 是 lastin 妒忌，让它去，结果可能是悲惨的一些 yall aint writin 很好地，太关心的由于流行你没有一个 aint gizell，猫走而且想像 Alotta yall 好莱坞，戏剧，通过了它削减母狗，照相机走开，真正的粪，摧残它而且如果我必须放弃你它的唯一是一年现在我使我的脚通过门而且我无处的 aint goin 它一会儿拿让我获得录取而且 Im 去从容不迫 Dont 在你的耳朵中对抗好粪现在让我吹 ya 思想他们想要存入银行在，上面曲柄提高，使我晕眩胫向上，憎恨者想要跟随我你 aint ganster，玩皮的人，太很多的吃在我的路径的蛇想要仰头对我笑现在当你的时候 grittin 你的牙齿挫折纵容你必须呼吸带 alot 更多你免除我你见到我做他们所讲黑话的做，我仅仅做我 Aint 没有压迫力当它来举行的时候，拿你见到的在实验室，钢笔和填补中遇到我， dont 相信哼！，十六我的，产生我自己的线为我的文字的争论爱那难者找二年级学生，我 aint 惊吓，一类型全部我做是注视方法使你的狂热者成为我的眼睛充血的， stressin，寒冷在你的背骨上面哼！，你的胃 wishin 的病人我写了你的台词而且如果我必须放弃你它的唯一是一年现在我使我的脚通过门而且我无处的 aint goin 它一会儿拿让我获得录取而且 Im 去从容不迫 Dont 在你的耳朵中对抗好粪现在让我吹 ya 思想让你的骨头裂缝你的背部取出，我讲黑话停止刺激， glock 注射从你的藏起来盒子性交它，宗教性暗杀团员出，我尊敬现金路径锁了下来， blastin ，组当我调情出的时候是的 nigga，调情出， D-R-E 支持轨道，向后地想，电子 V-E 做你相似的，你到达我认识你也在来自地板的梦幻之境第一一瞥中有了你 Dont 相信生病的表演你，和我带你把你打开，发给退休金离去，给你减轻当你听我的话时候，把你的信赖放入一个炸弹 Dancin 很多，拿它全部？

The conventional automatic selector lever in the centre console is replaced by a lever on the steering column, which the driver nudges to select the transmission settings "","N","R" and "D".

中心控制台的传统自动的选择者杠杆被在掌舵专栏上的一个杠杆代替，选择传输设定& P&，& N&，& R&和& D&哪一驾驶员用肘轻推。

He and Nina moved to California and lived at 2005 Ivar Street, Apt.

他和Nina搬到加州，并在2005年伊瓦尔街，公寓生活。

Droperidol （ potently inhibits transfected HERGchannels and this is the probable mechanism for QT prolongation.

氟哌利多有效地抑制了转染的 HERG 钾通道，可能是 QT 间期延长的机制。