风湿病的

Parthenolide is extract from feverfew, it's main component is sesquiterpene, it is commanly used in west country and is mainly used to therapy skin infection, rheumatic disorder, migraine. But recent research indicate that parthenolide can regulate many pathway of signal in the cell, inhibit the cyclooxygenase, TNF-α, interleukin-1 expression induced by lipopolysaccharide in macrophage, inhibit the iNOS expression in human monocyt, inhibit the activity of NF-κB in Hela cell, inhibit the growth of tumor cell and can relieve the myocardial ischemical reperfusion injury and so on. But the invention research about the effection of parthenolide on the VSMC is very rare in the world, so we do some research about the effection of inhibition of parthenpolide on the proliferation of VSMC and the signal transduction mechanism.

小白菊内酯(parthenolide，又名Sesquiterpene lactone)是艾叶菊属黑叶母菊的提取物，主要成分是倍半萜烯内酯，西方国家较为常用，主要用于治疗皮肤感染、风湿病和偏头痛，但近年来发现小白菊内酯能调控细胞内多种信号途径，如抑制巨噬细胞中脂多糖诱导的Cox，肿瘤坏死因子α和白细胞介素-1的表达，能抑制人单核细胞中iNOS的表达，能抑制Hela细胞中NF-κB的活性，抑制肿瘤细胞的生长，同时能减轻心肌缺血再灌注损伤等，但小白菊内酯在VSMC中的干预研究目前国内外非常罕见，为了确切评价小白菊内酯对血管平滑肌细胞增殖的抑制作用及相关的信号转导机制，我们进行了一些研究。

The company has the domestic and foreign advanced equipment, the craft and the stronger technical strength, and has many item of national level scientifie research achievement, the patent technology and three entir e automatic production 1 ines, At present goes on the market the principal variety has, in view of the diabetes paticent'' the new generation of Jinyu capsule, the Yuquan granular, the sealwort capsule, the Job's-tears capsule, the Chinese yam capsule''the preparation,''the multi-dimensional vein extends in view of the diabetes illness complicati on sickness patient ,the sugar full rice polishings''the high blood fats hypertension the multi-dimens ional capsule'' the mammmary gland proliferation''health care pastes in view of the mammary gland-proliferation disease, the rheumatism ossein proliferation disease''the ossein proliferation externally applies disperses''the chronic pharyngitis dis ease''XiaXingli the granular qranulew,for exprot adj ustment blood sugar product''Tarhucgranular and so on pure Chinese native medicine preparation.

公司拥有国内外先进的设备、工艺和较强的技术实力，并拥有多项国家级科研成果，专利技术和三条全自动生产线。目前上市的主要品种有，针对糖尿病患者的&新一代金玉胶囊、玉泉颗粒、黄精胶囊、薏苡仁胶囊、山药胶囊&制剂，针对糖尿病并发症患者的&多维脉络舒、尿足糠&高血脂高血压的&多维胶囊&针对乳腺增生疾病的&乳腺增生保健贴&，风湿病骨质增生疾病的&骨质增生外敷贴&慢性咽炎疾病的&夏星利咽颗粒&，供出口的调节血糖产品的&肽活颗粒&等纯中药制剂。

A moonlit garden, with its fragrant odors and dew-drenched grass, may mean all that is charming to you, while to another it brings only thoughts of asthma or fever or rheumatism. A color may be green to you that to another is red. A prospect may be inviting for you that to another is rugged and hard.

月光下的花园，弥漫着芬芳的气息、铺满带露的青草，对你而言也许十分迷人，但在其他人看来很可能这个地方会引起哮喘、感冒发烧或者风湿病；你眼中的绿色可能在另一个人眼中就是红色，对你具有吸引力的前景也许在他人看来是一条荆棘满布的路途。

"It were well," muttered the most iron-visaged of the old dames,"if we stripped Madam Hester's rich gown off her dainty shoulders; and as for the red letter, which she hath stitched so curiously, I'll bestow a rag of mine own rheumatic flannel, to make a fitter one!"

&我看啊！&一个面孔板得最紧的老太婆咕哦着，&要是我们能把海丝特太太那件讲究的衣袍从她秀气的肩膀上扒下来，倒挺不钱；至于她绣得稀奇古怪的那个红字嘛，我倒愿意货给她一块我害风湿病用过的法兰绒破布片，做出来才更合适呢&

"It were well," muttered the most iron-visaged of the old dames,"if we stripped Madam Hester's rich gown off her dainty shoulders; as for the red letter, which she hath stitched so curiously, I'll bestow a rag of mine own rheumatic flannel, to make a fitter one!"

&我看啊！&一个面孔板得最紧的老太婆咕哦着，&要是我们 sSBbWw 能把海丝特太太那件讲究的衣袍从她秀气的肩膀上扒下来，倒挺不钱；至于她绣得稀奇古怪的那个红字嘛，我倒愿意货给她一块我害风湿病用过的法兰绒破布片，做出来才更合适呢I&

"It were well," muttered the most iron-visaged of the old dames,"if we stripped Madam Hester's rich gown off her dainty shoulders; and as for the red letter, which she hath stitched so curiously, I'll bestow a rag of mine own rheumatic flannel, to make a fitter one!"

&我看啊！&一个面孔板得最紧的老太婆咕哦着，&要是我们能把海丝特太大那件讲究的衣袍从她秀气的肩膀上扒下来，倒挺不钱；至于她绣得稀奇古怪的那个红字嘛，我倒愿意货给她一块我害风湿病用过的法兰绒破布片，做出来才更合适呢I&

If you are unfortunate enough to the lovelorn, please tell me, I will help you out, really, please contact me!

如果你不幸失恋了，请告诉我，我会帮助你摆脱困境，真的，请联系我啦！

China's plan to cut energy intensity by 20 percent and pollutant discharges by 10 percent between 2006 and 2010 is a case in point.

中国计划在2006年到2010间降低20%的能源强度和减少10%的主要污染物排放，就是一个这样的例子。