靶

Ketamine anesthesia suppressed such regions as sensory cortex, motor cortex, thalamus and callosal gyrus, which might be the key targets for ketamine action.

氯胺酮麻醉抑制感觉皮层、运动皮层、丘脑和扣带回区域信号强度，而这些区域则可能是氯胺酮作用的靶位。

Methods: On the basis of the stereotactic, 37 patients who suffered affective disorder with compulsions were treated by stereotactic technique combined with 3.0 T Magnetic Resonance, Nervousness Navigation System and Electric Impedance Methods with bilateral amygdaloid nuclei, anterior limb of internal capsule, callosal gyrus, nucleus accumbens septi lesion by radio-frequency thermocoagulation.

在立体定向基础上，应用3.0T高场强核磁共振、神经导航系统和微电极电生理技术进行核团定位，对37例以强迫症状为核心症状情感障碍患者行立体定向杏仁核、内囊前肢、扣带回、伏隔核多靶点联合毁损术。

Via the experimental study of HWJND to SUs model in rat, we discovered that HWJND can reduce the excretive capacity of gastric juice and cankerous index of gastric mucosal, increase the content of GMBF, PGE2 in gastric mucosal, depress the content of NO and iNOSmRNA in gastric mucosal etc at a certain extent according to 15、 20 or 25g medicinal materials/kg avoirdupois. The results have statistic significance (p. 05-0. 01).It clues to that HWJND

和胃降逆方能通过多种途径多种机制表现出对SU模型大鼠胃粘膜的防护作用，同时体现了中药多成分、多靶点、多作用环节的特点，而和胃降逆方具有保护应激性溃疡作用是否影响与应激性溃疡相关的其它因素，还有待进一步深入研究。

Objective:To investigate the effect of cantharides infections on LoVo cell.

复方斑蝥注射液是从斑蝥、刺五加、黄芪、人参等中药中经现代独有的高科技工艺提取的新型多靶点抗肿瘤药，具有抗肿瘤和免疫调整双重作用，在临床上得到了广泛的应用。

In order to overcome the problem of multidrug resistance in human epidemic carcinomata anti-adriamycin cells (KB-A-1), the antisense and antigene oligonucleotides were used to investigate their effectiveness on inhibiting the mdr1 gene expression. The effectiveness of antisense or antigene oligonucleotide on inhibiting the multidrug resistance was detected by MTT colometric assay and ELISA.

中文题名反义与反基因寡核苷酸及其萘二酰亚胺偶联物对靶基因表达的抑制作用研究副题名外文题名 The inhibition of the targeted gene expression by the antisense or antigene oligonucleotides and their naphthylimide-conjugated derivatives 论文作者李军生导师张元兴魏东芝教授学科专业生物化工研究领域\研究方向生物化学与分子生物学学位级别博士学位授予单位华东理工大学学位授予日期2001 论文页码总数106页关键词基因表达基因治疗反义寡核苷酸反基因寡核苷酸核酸馆藏号BSLW /2001 /Q78 /264 针对人表皮癌抗阿霉素细胞株（KB-A-1）的多药抗药性问题，本文从反义核酸和反基因核酸角度，通过MTT法检测细胞生长情况，ELISA法检测基因表达产物P-gp表达水平的变化，对寡核苷酸抑制肿瘤细胞MDR1基因表达的机制进行了探讨。

Cealangulin V, isolated from Celastrus, is a kind of active compound for insects. It may has new target in the body of insect.

对天然产物进行研究，从中寻找先导化合物或新的作用靶标是创制新农药的重要途径。

The hemolysin consists three components,B,L1,and L2(35.36.and 45kDa,respeotively),combinations of all three moieties produed the unique ring-shaped zone of hemolysis,increased rabbit vascuolar permeability,caused fluid accumulation in rabbit ileum loop and appeared cellulotoxic reaction on Vero cells.

溶血素由B、L1和L2 3种成份组成，分子量分别为35、36和45kDa 3种成份的协同作用在血琼脂上引起靶状溶血，使兔皮肤血管通透性增加，兔小肠肠段结扎产生积液反应，Vero细胞形态学改变。

At the target surface impinged by the synthetic jet, the temperature field is symmetric with the lowest filed in center. The heat transfer coefficients also take on the same trends with centrosymmetric waves, which means that the best cooled area is the stagnation.

在冲击靶板上，整个冲击区域呈现出中心温度最低的近似圆形的对称性分布，对流换热系数曲线呈现出中心对称的波峰分布形状，表明自耦合射流驻点区换热最强。

Thunberg Fritillary Bulb is one of the most popular Traditional Chinese herbs. Some trials in vivo and animals indicated that Peimine and Peiminine, extracted from Thunbery Fritillary Bulb, have the function of reversing MDR of two different kinds of mechanisms. They can improve the cytotoxic of ADR to cancer cells by 5～10 folds under concentration of 10% cancer cell growth inhibitory rate. Peimine and Peiminine not only feather typical character of modifier of MDR, but also differ from other moldifiers such as Calcium channel blocker, Cyclosporines in chemical structure, they belong to cevine groups alkaloid, a subgroup of C-Nor-D-homosteroid alkaloid.

浙贝母是临床常用中药，体外及动物试验证明，浙贝母中的有效活性成分贝母甲素和贝母乙素具有逆转肿瘤细胞MDR的作用，而且能逆转两种不同机制的多药耐药肿瘤细胞的耐药性，在无明显细胞毒剂量下，可使阿霉素对耐药肿瘤细胞的杀伤活性提高5-10倍，不但具备明确的多药耐药逆转剂的特征，而且在化学结构上属异甾类生物碱中的瑟文类生物碱，完全不同于钙离子拮抗剂、免疫抑制剂和其它现有的耐药逆转剂，具有作用靶点宽、化学结构独特的特点。

XIAP may play an important role in the chemoresistance which might serve as a new therapeutic target for oral squamous cell carcinoma.

XIAP在口腔鳞癌中的表达水平升高，可能与鳞癌的化疗耐药性有关，这可作为口腔鳞癌基因治疗的一个新靶点。

I will endeavour to find you some assistance.

我尽力帮你找人帮忙。

At first I only know bruck is the idol of American younglings, afterwards I returned back to Taiwan ,even in Beijing last year ,I saw her poster everywhere, I was so surprised at her charm.

起初我只晓得布鲁克雷德丝是美国少男少女崇拜的偶像，后来回台湾，甚至去年在北京，居然也四处看见她的海报，才惊讶她的魅力之大。