霍乱

Aetiological agents of cholera. These strains have two main virulence-associated factors, cholera toxin and toxin co-regulated pilus.

这些致病性的菌株含有两个主要的与毒力有关的因子：霍乱毒素和霍乱毒素协同菌毛。

Aetiological agents of cholera. These strains hae two main irulence-associated factors, cholera toxin and toxin co-regulated pilus.

这些致病性的菌株含有两个主要的与毒力有关的因子：霍乱毒素和霍乱毒素协同菌毛。

Methods Four pairs of primers were designed from toxin sub-unit A gene, O139 special gene, Haemolytic subunit A gene and Toxin coregulated pilus subunit A gene. Multiplex PCR was established to simultaneously detect those four genes.

分别针对霍乱弧菌肠毒素A亚单位基因、O139群特异基因、霍乱弧菌溶血素A亚单位基因和毒力协同调节菌毛A亚单位基因设计引物，建立多基因PCR方法。

Cholera is a disease which affects the small intestine and is caused by bacterium vibrio cholera.

霍乱是一种疾病，影响小肠和细菌引起的霍乱弧菌。

Objective To study the germicidal effect of disinfectant on vibrion cholerae of El Tor biotype in different water bodies and to set a guidelines for disinfection in the epidemic foci of cholera.

目的 研究消毒剂对不同水体中ElTor霍乱弧菌的杀灭作用，为霍乱疫源地的消毒提供指导。

The highest titer of anti-CT mAb (CT-3A and CT-9A) determined by indirect ELISA was 1:15,625. Secondly, we made the colloidal gold from the chloroauric acid (HAuCl4) and labeled anti-CT mAb with the 20 nm colloidal gold.

第二部分进行胶体金合成工作，并成将霍乱毒素单株抗体与20 nm胶体金进行抗体染色，进一步应用於霍乱毒素免疫分析试片之开发上。

Objective To research on the lysogenic bacteriophage CTXΦ genome, for isogenous sequences with RS in the chromosomes were found in some strains of ctxAB- E1 Tor biotype isolates in this lab.

目的 近年研究发现产毒霍乱弧菌的毒素基因ctxAB由其溶原性噬菌体CTXΦ编码，这种丝状噬菌体可携带ctxAB传递给无毒素基因的霍乱菌株。

Different from the importation characteristic before 90s, strains after 90s were highly isogenous, suggested that the cholera epidemics in Sichuan province after 90s were endemic source. Inaba 1d strains from national wide epidemic in 2001 and 2002 were the same RT. Strains typed as different phagetypes (phagetype 6, phagetype 13 and phagetype 1) might be from a same clone.

除82-007、95-001外，所试菌株均具有致病性；20世纪90年代以四川省发生的霍乱为输入性，90年代后四川省流行的菌株高度同源，具有地方疫源性；2001、2002年在四川省乃至全国引起流行的稻叶1d为同 RT型，为传入性霍乱；噬菌体分型6型、13型菌株和1型菌株可能来自同一克隆系。

Different from the importation characteristic before 90s, strains after 90s were highly isogenous, suggested that the cholera epidemics in Sichuan province after 90s were endemic source. Inaba 1d strains from national wide epidemic in 2001 and 2002 were the same RT. Strains typed as different phagetypes (phagetype 6, phagetype 13 and phagetype 1) might be from a same clone.

除82-007、95-001外，所试菌株均具有致病性；20世纪90年代以前四川省发生的霍乱为输入性，90年代后四川省流行的菌株高度同源，具有地方疫源性；2001、2002年在四川省乃至全国引起大流行的稻叶1d为同一RT型，为传入性霍乱；噬菌体分型6型、13型菌株和1型菌株可能来自同一克隆系。

The fermentation rates of mannitol in toxigenic and non-toxigenic El Tor strains of Vibrio cholerae are obviously different,which is a valuable indicator in the rapid identification of toxigenic strain.

产毒和非产毒的El Tor生物型霍乱弧菌对甘露醇发酵利用的速率有明显差别，在霍乱致病株的快速判断中有重要的参考价值。

What are your goals and strategies for growth?

你的成长目标和策略是什么？

And unto the angel of the church in Sardis write; These things saith he that hath the seven irits of God, and the seven star I know thy works, that thou hast a name that thou livest, and art dead.

3：1 你要写信给撒狄教会的使者，说，那有神的七灵和七星的，说，我知道你的行为，按名你是活的，其实是死的。