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The JHU researchers prospectively examined changes in fibrosis stage between paired liver biopsies in 67 coinfected patients. Of the 67 subjects, six were excluded due to cirrhosis on the first biopsy. The median age of group was 44 years, and 75% of the subjects were men. A total of 86% had CD4+ cell counts of less than 200 cells/mm3, and the same number of subjects were receiving antiretroviral therapy. Twenty-seven percent of the patients abused alcohol. The median time between biopsies was 2.84 years (interquartile range, 2.05 - 3.41 years).

JHU研究人员前瞻性地检验67位共同感染病患成对肝脏切片的纤维化严重度变化,在67位受试者中,6位因在第1次肝脏切片时就已经是肝硬化而被排除;受试者平均年龄为44岁,而且75%的受试者为男性;86%患者的CD4+细胞计数低於200 cellsmm3,而且同样数目的受试者接受抗反转录病毒药物治疗;27位病患有酗酒的习惯;切片之间的平均时间为2.84年(四分位数中距为2.05-3.41年)。

The object of this study is to cancerous and normal cells intimacy of hematoporphyrin derivative for diagnosis and therapy cancer, fluorescence spectra of cancerous and normal cells are measured using a ultrashort pulses laser spectral technique and picosecond time-correlated single-photon counting system.

研究用于癌症诊断与治疗的光敏剂血卟啉(hematoporphyrin derivative, HPD)对人体癌细胞与正常细胞的亲和性,采用超短脉冲激光光谱技术和皮秒时间相关单光子计数系统,测量经血卟啉培养的活体癌细胞与正常细胞的荧光光谱,观测到癌细胞样品在创645nm处具有特有的光谱谱峰;测量不同浓度血卟啉荧光光谱,观测到随着血卟啉浓度的逐渐增大,在645nm处出现的光谱峰也随之显著增强。

Saintly . His convictions needed an Aaron to make them widely effective; and he found a voice in his pupil, the "bright and beautiful" Froude, whose short life (1802-36) counts for much in the Oxford Movement.

他的信念,需要一亚伦,使他们广泛有效的;他发现一个声音在他的瞳孔,"光明和美丽的"佛洛德,其短暂的一生( 1802年至1836年)计数的大部分时间在英国牛津运动。

As the DDP group A549DDP cells were treated with IC10 of cisplatin for 48 hours. As the DDP+Rh2 group A549DDP cells were treated with IC10 of cisplatin and IC5 of gensenoside Rh2 for 48 hours. As the controlling group A549DDP cells were not treated with any kinds of drugs. Changes in cellular morphology were observed by fluorescence microscopy. Peak value apoptosis of A549DDP cells were inspected by flow cytometry. State of PTP was evaluated by ultraviolate spectrofluorometer. Changs of calcium in cells and membrane potential of mitochondrion were determined by flow cytometry. Release of cyt-c from mitochondrion with westton blot Radiative activity of〓Tc-MIBI ingested by cells was measured withγcounter. Results: IC50 of cisplatine to A549 cells was 24uM.

以无毒浓度的Rh2单独作用于A549DDP细胞作为Rh2组,以低效浓度的顺铂单独作用于A549DDP细胞作为DDP组,以无毒浓度的Rh2和低效浓度的顺铂联合作用于A549DDP细胞作为Rh2+DDP组,作用时间为48小时,以不加药物干预作为对照组,Hoechst33258染色荧光显微镜下观察细胞形态的变化,流式细胞仪检测细胞凋亡峰;紫外光分光光度计检测线粒体PTP开放情况,流式细胞仪检测细胞内钙离子浓度及线粒体跨膜电位的变化,Westton blot检测线粒体内细胞色素C释放情况及Caspase-3的活性,γ计数仪检测细胞摄取〓Tc-MIBI放射性活性。

Methods The compound preparation was administered intragastrically in mice, whose spontaneous activity was observed along with their tolerance of the preparation after long-term administration. The hypnotic effect of the compound was assessed by investigating the changes in the pentobarbital sodium-induced sleeping. The compound was tested for its antiseizure effect in mice with pentetrazole-induced clonic and tonic convulsion. Diazepam was used as the standard control in all experiments.

利用光电计数法观察灌胃给予复方酸枣仁油栀子油对小鼠自发活动的影响,以及长期使用药物对小鼠耐受性的影响;利用延长戊巴比妥钠睡眠时间实验和戊巴比妥钠阈下催眠剂量实验,观察复方酸枣仁油栀子油的催眠作用;利用戊四氮诱发小鼠阵挛性、强直性惊厥观察复方酸枣仁油栀子油的抗惊厥作用;本实验用地西泮进行平行对照实验,并进行了组方设计和实验。

Methods Seventy-eight adult female PVGrats were divided into experimental group (n=60) and control group (n=18), intraneural injection technique was used to supply three kinds of NO donors with different half-life(DETA NONOate, DPTANONOate and Spermine NONOate) or saline into the rat sciatic nerve subperineurally under light microscope. At the 1th,2th,3th,7th,and 14th day of duration after sciatic nerve injection, a segment of injected sciatic nerve was taken out and embedded it in TAAB resin after tissue processing. Then it was cut into thin layers (1μm) and the histological changes were observed under high power microscope, meantime the number of degenerated axons were counted.

选择78只雌性PVG大鼠,分为实验组和对照组,以在体神经内微注射实验方法,将三种半衰期不同的NO供体(DETA NONOate,DPTA NONOate和Spermine NONOate)及生理盐水分别注入大鼠左侧坐骨神经的神经束膜下,于注射后的不同时间(1天、2天、3天、7天和14天)取出注射部位的坐骨神经,经组织学处理后做成树脂包埋块,以超薄切片机切片,然后在高倍显微镜下观察并计数神经横断面的变性轴突数目。

According to the bactericidal assay of quantitative vehicle, the bacteria on the ozonized vehicles and unozonized vehicles was washed, 50μl eluant was seeded on the TSA plates.

用碘滴定法测定打开臭氧发生器不同机组及不同时间时的臭氧浓度,按载体定量杀菌试验,将经臭氧作用的载体与相同环境下未经臭氧作用的载体上的细菌洗下,各取洗脱液50μl,接种于TSA平板并置厌氧箱(90%N2,10%CO2,37℃)培养24-48h后,进行活菌菌落计数。

In order to discuss the harm of long-time surfing the internet to the human body, we extract 35 undergraduate in our university and carry on the net continuously experiment. At the same time, 23 people (male 15 person, female 8 person) have been sampled on the track inspection on routine blood index. We discovered that continual 56 hour surfers can c ause obvious blood corpuscle metabolism function disorder, There are radical ascensions concerning the absolute value of blood routine inter cells, the number of white blood cells, the volume and quantity of the blood platelet and so on. The average volume of the red blood cells reduces significantly. The distributing volume and width of the red blood cells increase correspondingly.

为了探讨长时间上网对人体的危害,我们抽取在校本科大学生35人进行连续上网实验,对其中的23人(男15人、女8人)进行了跟踪血常规检查,结果发现连续56小时的上网,导致受试者出现明显的血细胞代谢功能紊乱,血常规中间细胞绝对值、白细胞计数、血小板体积及数量等多项指标出现应激性升高,平均红细胞体积显著性降低,红细胞体积分布宽度百分比明显增高。

Before the ages were named or numbered, our people were glorious and eternal and never-changing.

在年份和时间都还没有被命名和计数的时候,我们的人群曾是荣耀的,永恒不变且不会衰老的。

In the design of the system, one method of intelligent control is used which combines the Programmable Logical Controller and the Sensor, uses the shaft-type sensor to gather vehicles pulse and the high speed counter of the PLC to count the number of the pulse, uses certain principles of intelligent control to adjust the length of traffic lights automatically according to the data obtained, reduces the phenomenon of the vehicles stranded in a large scale, solves the problems of not equilibrium and unstable traffic flow magnitude well.

在系统的设计中,主要使用了PLC可编程序控制器和传感器相结合的一种智能控制方法,使用压轴式传感器采集车辆脉冲,用PLC高速计数器时脉冲进行计数,根据取得的数据运用一定的智能控制原则自动调节红绿灯的时间长度,最大限度地减少车辆滞留现象,较好地解决了车流量不均衡、不稳定问题。

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Chrysanthemum of 10 thousand birthday is lax to edaphic requirement, with the arenaceous qualitative loam with fecund, good drainage had better.

万寿菊对土壤要求不严,以肥沃。排水良好的砂质壤土为好。

He unstepped the mast and furled the sail and tied it.

他拔下桅杆,把帆卷起,系住。

Therefore, positively advances the interest rate marketability reform is one of current our country finance reform important tasks.

因此,积极推进利率市场化改革是当前我国金融改革的重要任务之一。