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纯合基因

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Nevertheless, Smoking could interact with wild type of NAT2 and increase the relative risk of rectal adenoma recurrence significantly. It is suggested that NAT2 might involve the metabolism of pre-carcinogen generating from tobacco and alter the susceptibility of cancer. Meanwhile, the NAT2〓4 alleles encode rapid acetylator of NAT2 would increase the risk of adenoma recurrence among those high-risk people with habit of fried fish intake.

吃红烧鱼因素在NAT2的快速酶中,特别是在野生纯合型中直肠腺瘤复发的相对危险度有增高趋势,提示了NAT2〓4等位基因编码快酶型NAT,可能在红烧鱼产生的杂环胺类化合物中代谢中加速其N-乙酰基化代谢过程,从而加速其代谢为终致癌物而与肠粘膜上皮细胞的DNA产生加成物,损伤其遗传物质。

The embryonic analysis results indicated that the disruption of oxt gene would lead to the disruption of wg transcription and the expression of engrailed gene, as the wg transcription is dependant on the Engrailed.

进一步结合运用FLP-FRT系统,用缺损GFP蛋白的表达来标记纯合的oxt突变基因克隆,针对眼睛成虫盘的克隆分析结果表明,在oxt突变克隆中,Hh下游的Ci蛋白的表达区域完全消失。

Objective To explore mutant types of β^0 homozygous thalassemia and clinical significance of Chinese traditional medicine.

目的 探讨β^0纯合子β地中海贫血的基因突变类型及使用中药益髓生血颗粒治疗的临床效果。

Objective To investigate the homozygous deletion of FHIT gene exon5, 8 and the expression of FHIT protein in gastric carcinoma.

目的:探讨FHIT基因外显子5、8纯合性缺失与蛋白表达的关系及其在胃癌发病机制中的作用。

Purpose: To chart the molecular genetic events in pancreatic cancer, we analyzed homozygous deletiongs in pancreatic cancer.

目的:为了探索胰腺癌癌变过程中的基因异常,研究胰腺癌基因组的纯合性缺失。

Results The homozygous deletion and methylation of p16 gen...

结果 P16基因纯合缺失 7例,甲基化 11例,总失活率为 2 6 。1%(18/6 9)。

No homozygous deletions were found in the MTS1 gene,while point mutations were found in 2 of 18 bladder cancers.

研究表明在多种肿瘤细胞中存在着MTS1基因的纯合缺失和点突变[3~7]。

Ideally an animal can be produced that is homozygous for the disrupted gene in all tissues.

理想情况下可以产生一只所有组织中对于目标基因来说是纯合的动物。

Such a plant is homozygous for every allele.

这样的植物对每个等位基因来说都是纯合的。

Methods Homozygous deletion of p16/MTS1 gene was examined by PCR methods in 68 cases of colorectal carcinoma.

方法采用聚合酶链反应方法,对68例结直肠癌组织中p16/MTS1基因纯合缺失进行检测。

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Chrysanthemum of 10 thousand birthday is lax to edaphic requirement, with the arenaceous qualitative loam with fecund, good drainage had better.

万寿菊对土壤要求不严,以肥沃。排水良好的砂质壤土为好。

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Therefore, positively advances the interest rate marketability reform is one of current our country finance reform important tasks.

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