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纯合基因

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In Small Tail Han sheep, Chinese Merino sheep, Corriedale sheep and South African Mutton Merino sheep, frequency of AA genotype was 0.58, 0.98, 0.96, 1.00, frequency of AB genotype was 0.40, 0.02, 0.04, 0.00, frequency of BB genotype was 0.02, 0.00, 0.00, 0.00, respectively. The ewes with mutation homozygous genotype BB or mutation heterozygous genotype AB had 1.45 at 305 bp of exon 3 of BMP4 gene in the BB genotype in comparison to the AA genotype, and this mutation resulted in an amino acid change: alanine—?aspartic acid. The ewes with genotype BB had 0.61 P

结果表明:小尾寒羊、中国美利奴绵羊、考力代绵羊在INHA基因5'调控区发生了1处碱基突变(316C→T),南非肉用美利奴绵羊没有发生这种突变;小尾寒羊、中国美利奴绵羊、考力代绵羊、南非肉用美利奴绵羊AA基因型频率分别为0.58、0.98、0.96、1.00,AB基因型频率分别为0.40、0.02、0.04、0.00,BB基因型频率分别为0.02、0.00、0.00、0.00;突变纯合型和突变杂合型小尾寒羊平均产羔数分别比野生型多1.45只P

The interactions between the alleles controlling the crossability of wheat with rye may exist.

小麦可杂交性基因间存在互作,表现为纯合隐性等位基因对其它显性等位基因的抑制作用,而纯合隐性等位基因间的效应具有可加性。

Dihyborid An organism that is heterozygous at two loci, formed by crossing homozygous parents with different alleles at two given loci: for example, Mendel ' s cross between yellow round and green wrinkled garden peas to give a yellow round dihybrid.

双因子杂交:用两个基因位点上具有不同等位基因的纯合亲本杂交形成的杂合生物体。例如,在孟德尔的杂交试验中,黄圆和绿皱杂交生成杂合子黄圆。

A person with a pair of identical alleles for a particular gene is a homozygote; a person with a pair of dissimilar alleles is a heterozygote.

一个人如果带有某个基因的两个相同的等位基因,是纯合子;如带有两个不相同的等位基因,则为杂合子。

Results Among 54 WD patients, 36 were found to carry Arg778leu mutation, among whom 15 were homozygote, 21 were heterozygote, the frequency of this mutation was 47.2%. Of 46 patients with hepatic damage, 36 were found to have the mutation of Arg778Leu, among whom 34 were found to have Leu770Leu polymorphism simultaneously.

结果 54例Wilson病患者中36例存在Arg778Leu基因突变,15例为纯合型,21例为杂合型,Arg778Leu等位基因突变频率为47.2 %;46例伴肝损害的患者中33例存在ATP7B基因外显子8的Arg778Leu突变;36例Arg778Leu突变者中34例同时伴有Leu770Leu多态性。

Among 13 DRB1 alleles detected in Drung ethnic, a unique feature of its allele distribution is having predominant homozygotes (64.9%) in all studied populations. In Drung HLA-DRB1〓14011 is highly prevalently presented with the allelic frequency of 70.07%.

独龙族中检出13种等位基因,其遗传学显著特点是纯合子类型检出较多,纯合子36个,占被检样品的64.9%,DRB1*14011分布占绝对优势,占被检出等位基因的70.07%。

Results In patients group,CBS genetic homozygous and heterozygous mutations were found in 9 cases and 28 cases respectively.

结果在脑梗死组有9例CBS基因纯合子突变,28例为杂合子突变;对照组3名为纯合子突变,5名为杂合子突变。

In most cases the SNP genotype of one parent was homozygous and the genotype of another parent was heterozygous, which were theoretically segregable in the progeny.

这些SNP在父母本中的基因型,在多数情形下,是一方为纯合,而另一方为杂合;父母本均为杂合和均为纯合的形式则较少。

Deduced by the proportion of typical sterile plants and normal fertile plants in segregative generations derived from WA zhenqiuA/6078 that:I gene could inhibit the expression of Rf gene completely by the heterozygosity of 1 pair of Rf in genotype;and only reduce the expression of Rf genes with two heterozygous Rf genes in genotype ;but it would never inhibit the expression of Rf genes if the genotype included 3 pairs of heterozygous Rf genes. When Rf gene was homozygous,the / gene could not inhibit the expression of it.

根据认叭真秋刀6078各衍生分离世代中典型不育株和正常可育株所占比例推断:基因型中仅包含1对杂合的Rf基因时,I对Rf的表达起完全抑制作用;基因型中包含2对杂合的Rf基因时,I仅对Rf的表达起削弱作用;当基因型中包含3对杂合的对基因时,I对Rf的表达不起抑制作用;I对纯合位点的Rf的表达不起抑制作用。

Methods:The difference of PTH gene and protein expression in parathyroid gland and thymus were compared between PTH knock-out mice 1αase knock-out mice and their wild-type littermates at 2 weeks of ages by RT-PCR,real-time PCR and immunohistohemistry.

real-time PCR和免疫组织化学的方法比较分析同窝2周龄PTH基因敲除纯合子和野生型小鼠以及1-α羟化酶基因敲除纯合子[1αase-/-]和野生型小鼠的甲状旁腺和胸腺的PTH表达差异?

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