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We couldn't see the line-relationship of the mute sites and the feather color types; maybe MC1R was just one major but not only silky feather color functional gene, the feather color maybe controlled by several genes. 8. There were length differences when using the same primer to amplify the mtDNA HVS-1 of black normal feather Wugu chickens and Guinea fowl.

在这些突变的氨基酸位点中,突变与羽毛颜色间除了丝羽乌鸡外均有一一对应关系,这可能提示乌鸡的丝羽口及颜色受多个基因的调控,MC IR基因可能是其中的一个主效但不是唯一的质量性状基因。

We couldnt see the line-relationship of the mute sites and the feather color types; maybe MC1R was just one major but not only silky feather color functional gene, the feather color maybe controlled by several genes.8. There were length differences when using the same primer to amplify the mtDNA HVS-1 of black normal feather Wugu chickens and Guinea fowl.

在这些突变的氨基酸位点中,突变与羽毛颜色间除了丝羽乌鸡外均有一一对应关系,这可能提示乌鸡的丝羽口及颜色受多个基因的调控,MC IR基因可能是其中的一个主效但不是唯一的质量性状基因。

They found duplicate fgfr1 genes in two varieties of mirror carp: One had lost 111 bases from the twin gene, and another had a base substitution in the twin gene, both of which had presumably led to fewer scales.

随后他们根据不寻常的特征筛查了发生突变的斑马鱼。其中的一个突变便是几乎全身没有鳞片,这不禁使人想起了镜鲤--为了容易打理而没有多少鳞片的一种鱼--的培育。

In this paper hIL-3 mutants hIL-3K116V and hIL-3K116W with substitutions at residue 116 lysine respectively by valine and tryptophan were generated by site-directed mutagenesis.

本文通过定点突变的方法使IL-3的第116位的赖氨酸分别被缬氨酸和色氨酸取代,获得了hIL-3的突变体hIL-3K116V和hIL-3K116W。

This method of primer design can be used to construct mutant plasmids with great ease and speed.

这种方法能用于超过20bp的碱基的插入或替代突变,及用于超过2000bp DNA片段的删除突变的研究。

Alpha-1 antitrypsin is the most abundant circulating protease inhibitor in the body, Dr. Lomas said. Its most common deficiency mutation is the Z allele, where the amino acid lysine is exchanged for glutamic acid at position 342 in the polypeptide chain (Glu342Lys). About 1 in 1700 whites of northern European descent are homozygotes for this mutation and thus have plasma antitrypsin levels that are 10% to 15% below normal, he said.

Lomas博士表示,甲一型抗胰蛋白酵素是身体内最充分的循环蛋白酶抑制剂,最常见的缺损突变在Z对偶基因,该处的胺基酸 lysine与麸氨酸在多胜肽链的第342位置交换(Glu342Lys);北欧血统白人每1,700人有1人是此一突变的同合子,因此血浆抗胰蛋白酵素值比正常低10%到15%。

Analysis of double mutants between bro-1(bp133) and several heterochronic mutants showed that the proliferative seam cell division occurred at any stage was defective in bro-1 mutation background.

对bro-1和不同异时基因构成的双突变的细胞谱系分析表明在L2时期以外时期出现的增殖性分裂也可以因为bro-1基因的突变而缺失。

A gene can be defined as the smallest hereditary unit capable either of recombination or of mutation. Alternatively it may be described as a unit of function, a CISTRON, which may be much larger than a unit of recombination or mutation, and controls the synthesis of a single polypeptide or a messenger RNA molecule whose genetic code is sontained within the gene.

基因是重组和突变的最小遗传单位,也可以被描述为一种功能单位———顺反子,顺反子可能比重组和突变单位大的多,它控制单个多肽的合成或合成含有遗传信息的信使 RNA 密码子。

Begg argues that all risk factors for breast cancer are overrepresented in incident cases of breast cancer, so that a sample of women who have been diagnosed with breast cancer and who are identified as mutation carriers are more likely to have other breast cancer risk factors than similar mutation carriers who are disease-free.

Dr。 Begg认为,所有的乳腺癌危险因子在乳腺癌病例中都被高估,所以一些已经被诊断为乳腺癌,且确认是某种基因突变的携带者妇女,比起具有相似的遗传突变的健康携带者,更可能是其他乳腺癌的危险因子导致疾病发生。

Begg argues that all risk factors for breast cancer are overrepresented in incident cases of breast cancer, so that a sample of women who have been diagnosed with breast cancer and who are identified as mutation carriers are more likely to have other breast cancer risk factors than similar mutation carriers who are disease-free.

Dr。 Begg认为,所有的乳腺癌危险因子在乳腺癌病例中都被高估,所以一些已经被诊断为乳腺癌,且确认是某种基因突变的携带者妇女,比起具有相似的遗传突变的健康携带者,更可能是其它乳腺癌的危险因子导致疾病发生。

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