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The key to using aberrant energy metabolism as a way to enhance site affinity that specifically targets the cancerous tumor cells' microenvironment that produces measurable tumor selective alkalinization involves administering an alkaline composition that has little toxicity to normal healthy viable cells which preferentially targets and elevates the pH level of the tumor micro-environment, thus causing the non-viability and apoptosis of tumor cells.

可使用异常能量新城代谢来提高瘤位置的亲和力,使瘤进行具有可测性、可选性的碱化,从而专门改变瘤细胞的微环境。其关键在于使用一种对正常健康活性细胞无毒性的碱性制剂,能优先提高瘤微环境的pH水平,从而使瘤细胞不具有生存能力,促使其凋亡。

Pathology findings:there were 294 cases of clear renal cell carcinoma (83.76%),including 2 cases of cystis renal cell carcinoma ,27 cases of Grannular renal cell carcinoma ( 7.69 %), 14 cases of papilliform renal cell carcinoma , 6 cases of the mixed type renal cell carcinoma,10 cases of other cell types . Followup was achieved in 263 cases (74.93%),with tie 3、5year and 10 year survival rates being 70.45 %(124/ 176),53.3%(40/75) and 23.8%(5/21) respectively.

病理结果:透明细胞294 例(83.76%,其中囊性肾细胞2例),颗粒细胞27 例(7.69%),乳头状肾细胞14例(3.98%),肾混合细胞6例(1.7%),其它10例。263 例(74.93 %)获得随访,随访时间6个月~12 年,3 年、5 年和10年生存率分别为70。

Pathology findings:there were, 294 cases of clear renal cell carcinoma (83.76 %), including 2 cases of cystis renal cell carcinoma , 27 cases of Granntdar renal cell carcinoma ( 7.69 %), 14 cases of papilliform renal cell carcinoma , 6 cases of the mixed type renal cell carcinoma, 10 cases of other cell types .

病理结果:透明细胞294例(83.76%,其中囊性肾细胞2例),颗粒细胞27例(7.69%),乳头状肾细胞14例(3.98%),肾混合细胞6例(1.7%),其它10例。263例(74.93%)获得随访,随访时间6个月~12年,3年、5年和10年生存率分别为70.45%(124/176)、53.3%(40/75)和23.8%(5/21)。

Methods: 9 cases of exogenic OVC、6 cases of cystoid and infiltrative OVC、15 cases of well-differentiation OSCC and 15 cases of poor-differentiation OSCC were selected; two specimens, which were carcinoma tissues and the sur...

方法取9例外生型口腔疣状、6例囊肿/浸润型口腔疣状、15例高分化鳞、15例低分化鳞,应用半定量逆转录多聚酶链式反应方法检测口腔疣状和口腔鳞中OPN mRNA的表达水平,应用免疫组织化学法检测上述标本中OPN的表达及分布,判断差异。

Clear cell carcinomas that may occur in the lower urinary tract include variants of the more common cancers such as prostatic adenocarcinoma and transitional cell carcinoma as well as infrequent carcinomas such as clear cell carcinoma, which is similar to that of mullerian origin and metastatic renal cell carcinoma.8 A benign process that occasionally has been reported to show marked clear cell change is nephrogenic adenoma, a lesion that is considered a benign metaplastic process.3,5,12 Perhaps because of the great histo

透明细胞可能发生在较低泌尿系统包括变异更常见的症如前列腺腺和过渡细胞以及罕见的如透明细胞,它是相似的苗勒管起源和转移性肾细胞 18亿美元的良性碾压工艺,偶尔被报告显示标记为透明细胞变化腺瘤,被视为是一种良性病变的化生 process.3,5,12也许因为伟大的历史

In part Ⅲ of this ariticle,The authors report some other neoplasms and precancerous changes, and they are adenoma of stomach, hemangiofibroma of ovary,carcinoma of Fallopian tube, osteo-petrosis,cholangiocarcinoma, polyps, leukoplakia,atypical hyperplasia, papillar...

这些肿瘤是鼻咽、副鼻窦、鼻腔、食管、卵巢,淋巴细胞性白血病、白色肉瘸、淋巴肉瘤,外阴、纤维肉瘤、原发性肝、小肠、结肠、乳腺,圆形细胞肉瘤、纤维瘤、脂肪瘤、马立克氏病、肾、畸胎瘤、膀胱乳头状瘤和口腔

Materials and Methods The triphasic dynamic enhanced CT findings of 52 patients with renal cell carcinoma were reviewed.

资料与方法回顾性分析52例肾患者的三期动态CT扫描资料,对经手术病理证实的透明细胞、乳头状、嫌色细胞3种肾亚型图像进行双盲法对比分析,比较肿瘤的大小、强化程度与模式(均匀、不均匀及主要周边强化)、有无钙化、出血、坏死与囊变、肿瘤扩散及淋巴结转移等情况,同时结合患者的性别和年龄,分析3种亚型肾之间的影像学差异。

RESULTS The positive rate of P-gp170expression in cervi-cal cancer pre-radiotherapy was58%(22/38).Among them,the positive expression rates were10/18(56%),6/10,4/6and2/4in keratinizing,nonkeratinizing squamous-cell carci-noma,adenocarcinoma and adeno-squamous-cell carcinoma respectively.The positive rate of post-radiotherapy was90%(34/38)and among them,the positive expression rates were16/18(89%),8/10,6/6and4/4in keratinizing,nonkera-tinizing squamous-cell carcinoma,adenocarcinoma and adeno-squamous-cell carcinoma respectively.

结果 宫颈组织P-gp170阳性表达在放疗前为58%(22/38),其中角化型、非角化型鳞、腺及腺鳞分别为10/18(56%),6/10,4/6,2/4例;放疗后其P-gp170阳性表达为90%(34/38),其中角化型、非角化型鳞、腺及腺鳞分别为16/18(89%),8/10,6/6,4/4例,P-gp170表达阳性强度较放疗前亦呈增高趋势。

Results: The isolating rate of upper gastrointestinal malignant tumor is12% and compare to the the people live in countryside and them in city, the ratio is four.esophageal carcinoma is 36%, carcinoma of gastric cardia is 9%,cardiac cancer associated with stomach is 32%, sinus ventriculi carcinoma is 10%.32% people lower 40 years old suffered from upper gastrointestinal malignant tumor is sinus ventriculi carcinoma, while esophageal carcinoma for young people is only 9%.

结果:上消化道恶性肿瘤检出率为12%,城乡差异达4∶1,食管占36%,贲门占9%,贲门胃体占32%;胃体占8%;胃窦占10%,40岁以下上消化道肿瘤检出40例,胃窦比例最高,占32%,其次为胃体,占27%,食管最低,仅占9%。

Methods Collecting 28 cases with sebaceous carcinoma in Head and Neck which was diagnosed with pathology. Of all these patients, the eyelid in 10 cases, parotid in 2cases, external auditory meatus in 5 cases, maxillofacial in 7 cases, neck portion in 4 cases, neck lymph node metastasis in 3 cases. They were treated with surgical operation, radical therapy and chemistry therapy.

收集28例经病理证实的头颈部皮脂腺患者的临床资料,其中眼睑皮脂腺10例;腮腺皮脂腺2例;外耳道皮脂腺5例;颌面部皮脂腺7例;颈部皮脂腺4例,颈部淋巴结转3例,采用手术、放疗、化疗等综合治疗。

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