略知

There are four kind of isoforms of endothelin in human and other mammals named ET-1, ET-2, ET-3 and ET-β, which are slightly different in construction and pharmacological effect. In human beings, ET-1 is the dominative subtypes. ET-1 remains in blood at a low level about 5ng per liter on physical state. It is synthesized, stored, released and metabolized locally. The half-life of ET-1 is about 1 hour. ET-1 is the most potent vasoconstrictive factor till now, and it is more functional in vein than in artery. In vascular bed, there are two kind of ET receptors. Type A mainly located in smooth muscle cells, whereas type B in endothelial cells. The latter can stimulate intimal hyperplasia via a parasecretion way and activate some oncogenes such as c-fos and c-myc and then enhance their expression. These alterations result in constriction of blood vessels, thus the SMC steps into proliferate state from silent state.

人及哺乳动物体内有四种结构及药理学性质略有差异的异物体，分别为ET-1、ET-2、ET-3、ET-β，而在人主要是ET-1，在生理条件下，ET-1在血浆中含量较低，约为5ng〓，故ET-1不是一个循环激素，而是局部合成释放，局部起作用的活性物质，半衰期约1小时，ET-1是目前已知的最强的血管收缩剂，对静脉的作用比动脉强，在血管床，ET受体有A、B两型，A型主要分布在平滑肌细胞，B型主要分布在内皮细胞，它可以通过旁分泌途径刺激内膜增生，具有有丝分裂原效应，可以激活某些癌基因如C-fos、C-myc使其表达增强引起血管收缩，使静止期SMC进入增殖期，还可以通过信号传导途径，与bFGF、GTF-β、PDGF等生长因子协同作用，起共有丝分裂原作用。

Velvet gowns this design idea is a very careful, because both sides have long-staple, and the back and silk lining, not only has the appearance of legislation plexus villi, the thickness of the larger and the effect of soft and cotton clothing with is similar to the good thermal properties, very sophisticated, but also very practical, is known in the ancient countries in the same fabric seems to have been found, even if placed velvet fabric with a modern bar, no less briefly indeed rare products, worthy of "mechanism cloud steaming, almost won Tiangong" the reputation.

这件绒袍的设计思想是相当周密的，由于两面均有长绒，而背面又有绢衬，不仅具有绒毛丛立的外观，厚度较大和手感柔软的效果，而且具有与绵衣相似的良好保暖特性，非常精巧，也非常实用，在现知古代各国的同类织品中似乎还没有发现过，即使将其置于现代绒类织物同列中，也略无逊色，实为难得的产品，无愧于&机制云蒸，殆夺天工&之美誉。

But by the time I have finished with my statement you will, perhaps, have a glimpse of what is raging within my breast to run this maddest risk which a sane man can run.

不过，我胸中到底是燃烧着一种什么样的东西，去冒一个理智的人所能冒的最大的风险，到我把陈述念完的时候，您就会略有所知。

Obvious ploys suggest to a prospective employer that you haven't researched the company and are just winging it. It's more effective to open with a business-related remark or a question that builds immediate momentum toward your goal of getting hired and fulfilling the employer's needs.

太明显的策略会让老板觉得你对该公司的了解还不够，只是略有所知，所以以与业务相关的评述开场或者首先提出一个问题会更有效，这个问题应该对你希望被聘用以及满足老板需求的目标产生立竿见影的效果。

As we know that notes are the summarization, the core content, our understanding and the abbreviations of the books.

如您所知，笔记是我们对所学课本的，中心，我们的理解和课本的缩略。

We know that notes are the summarization, the core content,our understanding and the abbreviations of the books.

如您所知，笔记是我们对所学课本的总结，中心内容，我们的理解和课本的缩略。

As we know that notes are the summarization, the core content, ourunderstanding and the abbreviations of the books.

如您所知，笔记是我们对所学课本的总结，中心内容，我们的理解和课本的缩略。

As we know that notes are the summarization, the core content, our understanding and the abbreviations of the books.

如您所知，笔记是我们对所学课本的总结，核心内容，我们的了解和课本的缩略。

As we know that notes are the summarization, the core content, our understanding and the abbreviations of the books.

如您所知，笔记是我们对所学课本的总结，中心内容，我们的理解和课本的缩略。

As we know that notes are the summarization, the core content, our understanding and the abbreviations of the books.

如您所知，笔记是我们对所学课本的总结，心内容，我们的理解和课本的缩略。

Life. But the intrinsic way of the Internet by wire confines accessing and using of the network information.

然而，Internet固有的有线连接方式大大限制了人们对网络信息的访问和使用。

I have a strong persuasion that this is true .

我坚信这是正确的。