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球海绵体肌

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Methods:Electromyographic response of external and internal anal sphincters to ischiocavernosus and bulbocavernosus muscle stimulation was studied in 17 healthy volunteers(10 men.7 women,mean aged 38.3± 11.6 years).

研究了17名健康志愿者(10男,7女,平均年龄38.3±11.6岁)的坐骨海绵体肌和球海绵体肌受刺激后肛门内、外括约肌的肌电反应。

Keywords bulbocavernosus muscle;ischiocavernosus muscle erection;sexual act;orgasm;erectile dysfunction

球海绵体肌;坐骨海绵体肌;勃起;性交;性高潮;勃起障碍

Bulbocavernosus muscle ; ischiocavernosus muscle erection ; sexual act ; orgasm ; erectile dysfunction

球海绵体肌;坐骨海绵体肌;勃起;性交;性高潮;勃起障碍

The male and female offspring were sacrificed at PND 56, 98, and 140 respectively. The prostate, levatro ani bulbocavernosus and bulbourethral glands relative weights at PND 56, and epididymis and LABC relative weights at PND 98 of ME group male offspring were increased significantly.

雄、雌性仔鼠分别於 PND 56、98 与 140 时牺牲,雄性仔鼠在 PND 56 的前列腺、提肛与球海绵体肌与尿道球腺,及 PND 98 时副睪与 LABC 相对重量明显上升;暴露组雌性仔鼠於 PND 56 时卵巢相对重量有明显上升,而在 PND 140 肝脏相对重量则显著下降。

Methods In 28 patients of ED caused by the posterior urethral injury complicated with pelvic fracture, diagnosis and classification were carried out by means of detail history, physical examination, laboratory examination, international index of erectile function, night penile test, papaverine test, penis Doppler ultersound, dynamicavernorography, bulbocavernosus reflex and urodynamics test.

通过病史、查体、实验室检查,国际勃起功能指数,NPT、罂粟碱试验、阴茎Doppler声、动态阴茎海绵体造影、球海绵体肌反射和尿动力学检查等方法,对骨盆骨折并后尿道损伤引起的阴茎勃起功能障碍28例患者进行诊断、分类,对不同类型的ED患者进行相应治疗。

To reseach the mechanisms of ED wtih DM from the acpects of endocrinology, morphology and molecular biology, using rats from NDM and STZ groups as control, the concentration of testosterone, LH and FSH in sera, the microstructure of testicular tissue, bulbocavernous and ischiocavernous muscle tissue, and penile cavernous tissue, the ultrastructure of penile cavernous tissue, and the expression of nNOS mRNA, the content of nNOS and eNOS, the activity of NOS and the concentration of cGMP in the pathway of LARG-NO-cGMP in penile cavernous tissue from ED rats with DM were reseached or examinated in Group A, B and C.

本实验利用第一部分所建立的DM性ED模型,采用NDM及STZ大鼠作对照,通过对A组、B组及C组DM性ED大鼠血清中睾酮、LH及FSH浓度的测定,睾丸组织形态结构的研究从内分泌方面探讨DM性ED的发病机理;通过对阴茎海绵体组织显微及超微结构和球海绵体肌及坐骨耻骨肌显微结构的研究,首次从形态学方面探讨DM性ED的发病机理;通过对阴茎海绵体组织L-ARG-NO-cGMP通路中nNOS mRNA表达、nNOS及eNOS含量、NOS活性及cGMP浓度的检测,从分子生物学方面探讨DM性ED的发病机理。

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