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The histopathologic changes included lymphocyte and monocyte infiltration,hyperplasia of synovial cells and small vessels,interstitial fibrosis,hyaline degeneration and cartilaginous metaplasia.The immunohistochemical observations showed that the high expressions of IL-1 and IL-6 were significantly different between the pathologic plicae and the control groups(P<0.01).The positive expressions of IL-1 and IL-6 were the synovial cells and monocyt-lymph cells in the pathologic synovial plicae.The positive expressions of MMP-1 and TIMP-1 have significant difference between the experiment and control group(P<0.01,P<0.05).The expression of MMP-1 was positive in synovial lining cell,monocyte,fibroblast,endothelial cell in small vessel and chondrocyte.The TIMP-1 expression was detected in the synovial lining cells and a small quantity fibroblast.

结果 正常滑膜皱襞和病理性滑膜皱襞在滑膜细胞增生及小血管增生、间质纤维化及玻璃样变、软骨化生组织学改变方面,差异均有显著性(P<0.01);IL-1、IL-6在病理性滑膜皱襞内的增生滑膜细胞、单核及淋巴细胞和在正常滑膜皱襞内的表达差异均有显著性(P<0.01); MMP-1、TIMP-1在病理性滑膜皱襞和正常皱襞内的阳性表达,差异具有显著性(P<0.01,P<0.05),MMP-1在增生滑膜衬里层细胞、单核和纤维母细胞、血管内皮细胞和软骨化生的软骨细胞呈阳性表达;TIMP-1只在滑膜衬里层细胞和少量纤维母细胞有表达。

Results: The rate of abnormal increase of telomerase activity was 75.71%, pos itive rate of telomerase was 31.41%,OD value was 388.21(×10-3) in hypertension group(70 cases) were significantly increase (P<0.01,<0.0 5,<0.01),comp ared with 47 cases' normal group(RAITA was 31.79%,PRT was 6.38%,OD value was 7 0.7).The difference of RAITA was not significance (P>0.05) between aged h ypertension group (73.68%) and normal group(52.63%),the difference of RAITA w as significance (P<0.05) between adult(age<60) hypertension group (7 5.00%) and normal group(17.81%). The difference of RAITA、PRT was no signific ance among 2 groups of hypertension, and was significanceP<0.05)among 2 g roups of normal.

结果:高血压病组(70例)端粒酶活性异常增高率(75.71%),阳性率(31.41%),OD值[388.21(×10-3)]分别明显高于正常组(47例)的 31.79%、 6.38%、70.7( P<0.01,<0.05,<0.01);老年高血压组的端粒酶活性异常增高率(73.68%)与正常同年龄组的52.63%比无明显差异,但成年(<60岁)高血压组的端粒酶活性异常增高率(75.00%)较正常组的17.81%明显增加(P<0.05);高血压2个年龄组的端粒酶活性异常增高率、阳性率、OD值无明显差异,但正常人2年龄组这些参数有明显差异(P<0.05)。

Methods 64 SD male rats were fed a normal diet for one week then they were randomly divided into two groups ,one was normal group(which were 12 rats)fed normal diet, the other , which were 52 rats fed high fatty diet for 12 weeks. At the end of 13th week, 2 rats from fed normal diet group and 8 rats from fed high fat diet group were scarified to test fatty liver model .

将雄性SD大鼠64只正常喂养1周后,随机分为正常组12只饲基础饲料,实验组52只给予高脂饲料饲食(含胆固醇2%,猪油10%,基础饲料88%),13周末随机抽取正常组2只、高脂饲养8只,验证高脂饲养大鼠脂肪肝形成。

The A type varied flowers with umbrella-inflorescence shape in female syconia affected pollination by fig wasps in normal female flowers, required more nutrients and growth space, and affected growth and development of normal female flowers. With a large number of type A flowers, unpollinated female syconia show delayed litter fall or hanging on the trees and loss of nutrients.

雌花序中伞形花序状的A型变异花影响传粉小蜂对正常雌花的授粉,与正常雌花争夺养分和生长空间从而影响正常雌花的生长发育,大量A型变异花的存在使未授粉的雌花序延迟凋落或挂树不落,造成养分流失。

A type variation flowers with umbrella-inflorescence-shape in female syconia affected the normal female flowers be pollinated by fig wasps, affected growth and development of normal female flowers for contesting nutrients and growth space. Being a great deal of A type variated flowers, unpollinated syconia were delay or not to fall, and resulted that the nutrient run off.

雌花序中伞形花序状的A型变异花影响传粉小蜂对正常雌花的授粉,与正常雌花争夺养分与生长空间影响正常雌花生长发育,大量A型变异花的存在使未授粉雌花序延迟凋落或挂树不落,造成养分的流失。

Under large-scale environment and so on building underlying bed, underground market, underground parking garage, the mobile communication signal is weak, the handset was unable normally to use, has formed the mobile communication blind spot and the shadow region; In among floor periphery, because comes from different base depot signal overlapping, has the pingpong effect, the handset frequent cut, even falls the speech, seriously has affected the handset normal use; In building high level, as a result of the base depot antenna high limit, is unable normally to cover, also is the mobile communication blind spot.

在大型建筑物的低层、地下商场、地下停车场等环境下,移动通信信号弱,手机无法正常使用,形成了移动通信的盲区和阴影区;在中间楼层,由于来自周围不同基站信号的重叠,产生乒乓效应,手机频繁切换,甚至掉话,严重影响了手机的正常使用;在建筑物的高层,由于受基站天线的高度限制,无法正常覆盖,也是移动通信的盲区。

Results: Compared with the C group, the contents of CORT in blood and ACTH in pituitary gland are increased at the different time points. Compared with the C group ,the contents of CR11 in Hypothalamus are enhanced in S and SAI groups on list but those are reduced in S and SM groups on 16st and 21st. Compared with the S group ,the contents of CORT in blood and ACH in pituitary gland are increased in SM group on 11 at. Compared with the SM groups, the contents of CORT in blood are reduced in TKXLD groups on 11st, l6st and 21st. Compared with the SAT group respectively, the contents of CRH in Hypothalamus are decreased in TKXLD group on list and those in TKXLD group are increased on 16st and 21st.

结果:实验第11、16和21天悬吊组和悬吊加辐射组大鼠血清CORT和垂体ACTH含量高于正常组;悬吊组和悬吊加辐射组大鼠下丘脑CRH含量在实验第11天高于正常组,在实验第16天和21天低于正常组;实验第11天悬吊加辐射组大鼠血清中CORT的含量高于悬吊组;实验第11、16和21天,中药组大鼠血清CORT含量低于悬吊加辐射组,垂体ACTH含量低于悬吊加辐射组;中药组大鼠下丘脑CRH含量在实验第11天低于悬吊加辐射组,在实验第16天和21天高于悬吊加辐射组。

RhoGDI (RhoGDP-dissociation inhibitor 1) and Cyclophilin A (Peptidyl-Prolyl Cis-Trans Isomerase A) were reported to differentially express in two studies, but their results were inconsistent.

其中mimecan在正常结直肠组织中强表达,却在腺瘤和癌组织中不表达;TXNDC5(Thioredoxin domain-containing protein 5)在正常,腺瘤和癌组织中都表达,腺瘤和癌组织的表达量显著高于正常(P<0.05);RhoGDI(Rho GDP-dissociation inhibitor 1)和Cyclophilin A(Peptidyl-Prolyl Cis-Trans Isomerase A)在两份研究中报道差异表达,却都是一个报道在结直肠癌中高表达,一个报道低表达。

Ethods Tissue specimens were stained immunohistochemically for MMP-2 and MMP-9 in 30 cases of squamous cell cervical carcinoma,29 cases of cervical intraepithelial neoplasia and 16 cases of normal cervices.

MP- 2鳞癌组与CIN组及正常组相比差异有极显著性(P 。0 1)。 MMP- 9正常组与鳞癌组及 CIN组相比差异有显著性(P 。0 5 )。MMP- 2在各组间质的基质细胞中表达均为阳性。MMP- 9在正常宫颈组织、CIN及鳞癌的基质细胞中阳性表达分别为 0 / 16 (0 %);4/ 2 9(13.8%);7/ 30 (2 3.3%)。各组间相比差异无显著性。

Pparent amino acid digestibilities and true amino acid digestibilities of six feedstuffs (barley,cooking blood meal,fermented blood meal,protein hydrolysate mixed feed,heatextruded collagen protein and local fish meal) and their mixed feeds(J1 and J2) were determined with intact and caecectomized cockerels,using Sibbaled "TME" method,and their additivities were also tested.

本研究以去盲肠鸡和正常鸡按Sibbald的&TME&方法分别测定了皮大麦、蒸煮血粉、发酵血粉、水解复合蛋白、热喷胶原蛋白、国产鱼粉及其配合饲料J1和J2的氨基酸表观消化率和真消化率。并对两种试鸡所测上述饲料原料氨基酸的消化率及其可加性作比较。结果表明:(1)6种饲料原料的某些氨基酸表观消化率和真消化率,去盲肠鸡和正常鸡测值间存在显著差异(P<0.05)。(2)去盲肠鸡内源氨基酸排出量显著高于正常鸡(P<0.05)。

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