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Results: The TRAP positive multinuclear cells were induced from rat marrow mononuclear cells after inoculating for 5 clays. RT-PCR analysis showed that ASIC1, ASIC2 and ASIC3 mRNA were present in the osteoclasts, and the corresponding proteins expressions were detected.

结果:诱导5d后可见抗酒石酸盐酸性磷酸酶阳性多核细胞出现,大鼠破骨细胞在mRNA和蛋白水平均可检测到ASIC1、ASIC2和ASIC3基因的表达产物。

Objective To explore the concentration changes of the serum acute-phase proteins,including α1-acid glycoprotein,α1-antitrypsin,haptoglobinand cernloplamin in patients with rheumatoid arthritis and seronegative spondyloarthropathy in active stage and their clinical significance.

目的 观察活动期类风湿性关节炎和血清阴性脊柱关节病患者血清4种急性时相反应蛋白α1-酸性糖蛋白、α1-抗胰蛋白酶、触珠蛋白和铜蓝蛋白浓度的变化及其临床意义。

And to study its antitumor activities. MethodsThe active fraction of Thlaspi arvense linn was extracted and identified by nethanol-extraction,tart-Al2O3 colum chromatography,TLC and HPLC.

方法采用甲醇萃取、酸性氧化铝层析柱层析和谱图分析对寨卡有效部位进行分离提取和鉴定,采用S180荷瘤小鼠模型和CT-26荷瘤小鼠模型,探讨寨卡有效部位提取物的抗肿瘤活性。

SPARC (secreted protein, acidic and rich in cysteine) is a multifunctional glycoprotein, which influences many important physiological and pathological processes, such as modulating cellular interaction with the extracellular matrix, abrogating cell focal adhesions, inhibiting cellular proli-feration, and regulating the activity of growth factors.

SPARC (secreted protein, acidic and rich in cysteine)即富含半胱氨酸的酸性蛋白,为一种多功能糖蛋白,在各种生理与病理过程中发挥作用,如调节细胞与细胞外基质(extracellular matrix, ECM)相互作用、溶解黏着斑完成抗黏附反应;抑制细胞增殖及调节生长因子活性等。

Bone resorbing osteoclasts contain high amounts of tartrate-resistant acid phosphatase 5b and secrete it into the blood circulation.

破骨细胞重吸收骨骼时包含大量的抗酒石酸酸性磷酸酶(TRACP 5b)并且分泌到血液循环之中。

Results Salivary amylases can both enhance and competitively inhibit the adhesion of the strain to HA, while IgA degraded fragments and MW=13 000 protein only promote its adhesion.

结果 唾液IgA降解片段和相对分子质量为13 000的酸性蛋白仅促进变链粘附,唾液淀粉酶具有促进粘附及抗粘附双重作用。

P1 and a 117 000 surface protein of WD9463A both inhibit adhesion of the strain to IgA degraded fragments and salivary amylases.

结果 唾液IgA降解片段和相对分子质量为13 000的酸性蛋白仅促进变链粘附,唾液淀粉酶具有促进粘附及抗粘附双重作用。

Crystal of crisp, pay attention to anti-stress, drop resistance, anti-heat, anti-alkali, strong acid.

的脆,注意防应激,抗跌落,防热,防碱,强酸性结晶。

Crystal of crisp, pay attention to anti-stress, drop resistance, anti-heat, anti-alkali, strong acid.

答:的脆,注意防应激,抗跌落,防热,防碱,强酸性结晶。

The results of this reseach showed that administration of SF intracolonically had protective effect on the colon injury in the rat model of colitis induced by acetic acid enema, which was probably due to the mechanism of antioxidation, inhibition ofarachidonic acid metabolis and platelets activation, administration of SF intracolonically also showed protective effect on the colon injury in the rat model of colitis induced by trinitrobenzene sulfonic acid and ethanol, which was probably due to antioxidation and inhibition of macrophages activation.

实验研究表明,大鼠分别经乙酸、TNBS和乙醇处理后均出现典型的结肠炎症状,给药后分别评价结肠粘膜损伤指标、结肠组织病理变化,检测结肠组织炎症指标、结肠组织氧化损伤指标及主要炎性细胞因子改变;实验结果:阿魏酸钠对大鼠乙酸性结肠炎结肠粘膜损伤具有缓解保护作用,其机制可能与直接抑制炎症结肠粘膜花生四烯酸代谢过度,抑制血小板活化,清除大量氧自由基有关;阿魏酸钠对大鼠TNBS性结肠炎粘膜免疫损伤亦具有缓解保护作用,其机制可能与抗氧化,抑制结肠巨噬细胞活化有关。

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