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Results: ApoD was observed positively expressed in type2 astrocytes and oligodendrocytes from O2A lineage, while it was not expressed in type1 astrocytes from T1A lineage. Accordingly, we can verify the phenomenon found in the study of T1A and T2A gene different expression profile that ApoD mRNA was highly expressed in T2A and lowly expressed in T1A. Conclusion: It can be concluded that lipid metabolism related genes such as ApoD play important roles in the generation and differentiation of O2A lineage, which closely correlate with internal mechanism of lipid metabolism in the brain and myelogenesis.[Key words]astrocyte(T1A, T2A); oligodendrocyte; O2A lineage; apolipoproteinApoD

我们已采用基因芯片技术在mRNA水平研究两型星形胶质细胞的基因表达谱差异,发现ApoD在2型星形胶质细胞中差异高表达,故本文拟用激光共聚焦双重免疫荧光标记技术进一步在蛋白质水平观察ApoD在体外分化成熟的两型星形胶质细胞以及少突胶质细胞中的表达情况,以期为我们深入研究ApoD等脂代谢相关基因在脑内脂质代谢和神经髓鞘发育机制中所起的作用提供有用的实验依据,依此探讨胶质细胞发生和分化的信号机制。

Myoblastic cells from patients with PM had a weaker ability of developing into the myotubules, thus they were unable to perform effective regeneration, which resulted in a progressive necrosis. The exogenous bFGF could promote the division and proliferation of the muscle cells in vitro . These results shield a light on bFGF's potential role in preventing and treating PM.

PM患者受损腓肠肌在体外有再生能力,但融合成肌管能力极弱,存在再生障碍,不能对变性、坏死的肌纤维形成有效再生,故呈进行性肌纤维耗竭;外源性bFGF可促进PM患者体外培养骨骼肌细胞增殖分裂,并可促进肌管成熟,对进展性肌病应具有防治作用。

All results above indicated that:The expression of ERβand p-ERβin mouse ovary at oestrous cycle and in early gestational period changed regularly, it showed that ERβand p-ERβhad important effects to ovaries development, ovarian follicles groth, oocyte maturation and form corepus luteum in female mouse ovary during oestrous cycle and in early gestational period.

以上结果表明:ERβ及其磷酸化形式——p-ERβ在小鼠发情周期以及妊娠早期卵巢中表达有规律性的变化,揭示ERβ与p-ERβ在雌性小鼠发情周期及妊娠早期,对卵巢发育、卵泡生长、卵母细胞成熟和黄体形成有重要的作用。

The neutralizing activity of these antibodies and IgG fractions is acquired through post-translational modifications, through opsonization of virus particles into macrophages and immature dendritic cells, or through expression of antibodies on the surface of HIV-1-susceptible cells.

这些抗体或IgG片段的中和活性可以通过抗体分子翻译后的修饰,或介导巨噬细胞和未成熟树突状细胞的对病毒颗粒的调理作用,或者通过表达在HIV易感细胞表面来体现。

As one of the important medicated factor of osteoclast activity, PTHrP can induce the differentiation and mature of osteoclast and play an important role during the genesis and development of osteolytic bone metastasis of breast cancer.

PTHrP作为重要的破骨细胞活性介导因子之一,诱导破骨细胞分化和成熟,在乳腺癌溶骨性骨转移的发生、发展中起着重要作用。

In this study, the effects of STH and insulin on porcine in vitro oocyte maturation and cleavage after parthenogenetic activation were investigated.

研究了生长激素、胰岛素单独或者联合作用对猪卵母细胞体外成熟及孤雌激活后卵裂的影响。

Objective: To investigate the parthenogenetic activation of calcium ionophore A23187 and puromyein on the human oocytes matured in vitro.

目的:探讨钙离子载体A23187或联合嘌呤霉素对人类体外成熟卵母细胞的孤雌激活作用。

Adances in our understanding of the phenotypical and functional plasticity of DCs, and in our ability to manipulate their deelopment and maturation in itro and in io, has proided a basis for the therapeutic harnessing of their inherent tolerogenicity.

我们进一步的认识到树突状细胞在表型和功能上的可塑性,发展了离体和在体地调控它们的生长与成熟的技术,并以此为基础提供了我们利用它们内在的致耐受性来发挥治疗作用。

Objective To study the maturation of the postural equilibrium in young children and the effects of eye-closure.

目的 研究健康儿童立位姿态平衡功能发展成熟过程以及视觉系统在儿童姿态平衡中的作用。

In order to trace the male cytoplasm transmission during double fertilization process, the mature gametophyte, zygote, proembryo and primary endosperm in Pelargonium hortorum Bailey and Rhododendron mucronulatum Turcz were investigated using transmission electron microscope and DNA staining technique.

本研究应用透射电镜及DNA荧光技术对天竺葵和杜鹃的成熟配子体以及在受精以后雄性细胞器的存在和分布进行了系统的细胞学研究,阐明了这两种植物中雌性生殖单位的超微结构特点及雄性和雌性细胞中质体和线粒体在受精作用中的传递。

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Since historical times,England ,where the early inhabitants were Celts, has been conquered three times .

从有历史以来,英国,在此地早期居住的是凯尔特人,已经被征服了三次。

Bluetooth OBEX File Transfer Enables the sending and receiving of files on your phone via Bluetooth.

蓝牙OBEX文件移动允许经过蓝牙传送和接受文件。。。。

The almost sure central limit theorem is a pop topic of the probability research in recent years,because it has many actual applications in the random analogue.

中文摘要:几乎处处中心极限定理是近几十年概率论研究的一个热门话题。它之所以引起人们的注意是由于它在随机模拟方面的实际应用参见Fisher