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Results indicated that the anaplasma could be observed by microscope in erythrocyte of experimental animals at 6th to 8th day, and the anaplasma reached peak number in erythrocyte at 16th to 20th day, disappearing at 25th day after infection.

结果表明,无浆体在小鼠和兔子体内呈现一定的规律性。无浆体在感染后第6d和第8d分别在小鼠和兔子血液中可以检测到;感染后第16d~19d和第17d~20d在两者体内达到感染高峰;感染后第20d和第25d均逐渐消失。

To establish anaplasma artificial infection model in experimental animals which treated with dexamethasone to investigate the transmission route of the pathogen, mice were infected via intra-abdominal and subcutaneous inoculation with the blood from infected cattle, the homogenate of infected gadflies and viscera of infected mice, contacting infected mice, respectively, while rabbits were infected through co-feeding with affected cattle.

采用地塞米松注射液长期抑制试验动物的免疫力,通过小鼠腹腔、皮下接种含有无浆体病原的奶牛血液、阳性厩蝇内容物、脏器悬液,并进行阳性小鼠接触感染和兔子临床同层感染等试验,研究奶牛无浆体的感染和传播及在试验动物体内的消长规律,建立起无浆体人工感染模型,调查临床中病原体的实际传播途径。

The result of the study shows that the morbidity of the hospital infection in 305 elderly died cases dis- eases was 33.8%, The lungs were the first major site of the infection (66.9%) and followed by urinary tract infection (19.4%), The factors of high risk in- ducing hospital infection included advanced age invasive procedures, multi-antibiotics used in com- bination and hormonotherapy.

本文结果表明,305例老年死亡病例医院感染的发病率为33.8%。感染最多部位为肺部(66.9%),其次为尿路感染(19.4%)。高龄患者,侵袭性操作、多种抗生素联合应用,激素疗法等是诱发医院感染的危险因素。58.8%的病原菌为革兰氏阴性杆菌,37.2%为真菌。31株病原菌药敏结果显示耐药率为33.3%。

Primary study showed that body weight of broilers infected with ALV-J or REV, compared with the control, was significantly depressed and antibody response to NDV vaccine was inhibited. In addition, these broilers were susceptible to bacterial agents, such as colibacillosis, causing higher lethality rate in early time.

初步研究表明:单独感染和混合感染均可引起感染鸡生长发育不良,中枢免疫器官萎缩,免疫器官指数下降,对特定疫苗免疫应答降低,同时感染鸡早期对细菌性疾病的易感性增加,死亡率升高。

These days,it scares many the folk for its cureless and more and more people are infected by HIV virus,the infected are discriminated to be sin and uncommiserable,and unfair of work,even life,most of them dare not to accept the therapy ,are they sin?

近几年来,中国越来越多的人感染了HIV病毒,这引起了很多人的恐慌,因为目前医学上还没有发明一种可以治疗AIDS的药物。很多人都认为感染了HIV是罪恶的,是不值得同情的,因而在各个方面都歧视他们,在工作上、生活中他们都受到不平等对待。从而很多感染了HIV的人都不敢接受治疗。难道感染了HIV的人都是罪恶的吗?

Difficile is not as strong as that between the infection and antibiotics.

然而,他强调,胃酸分泌抑制剂与难治梭胞杆菌之间的关系并不像感染与抗生素之间那样紧密;必须要重视的是,感染难治梭胞杆菌的最大风险是使用抗生素,而且住院老年病患的风险最高,我们必须了解难治梭胞杆菌引起的感染越来越常见,且越来越严重,因为新的抗药性菌种已经被发现,因为感染这些高抗药性细菌的病患对治疗反应不佳,这样的课题已经受到重视。

The dynamic changes of the number of T or B lymphocytes and the content of immunoglobulin G, IgM, IgA in peripheral blood, the number of CD〓, CD〓 lymphocyte subpopulation, T〓 cells and IgG, IgM, IgA antibody-producing cells, the ratios of CD〓 and CD〓 T cells in immune organs (thymus, bursa of Fabricius and spleen) and immune tissues (cecal tonsils and Harderian glands), the content of IgA, IgM, IgG in local fluid (tear, tracheal fluid, intestinal fluid and bile) of one-day chicks infected with chicken infectious anemia virus and CIAV-infected chicks immunized with Newcastle disease vaccine were determined respectively by immunohistochemistry, immunogold-silves and immunoenzyme staining in order to reveal mechanism of immunopathogenesis of chicks infected with CIAV and influence of immune responses of CIAV-infected chicks to ND vaccine.

中文题名雏鸡感染鸡传染性贫血病毒后免疫变化和对新城疫疫苗的应答及其免疫机理副题名外文题名 Immune changes of chicks infected with chicken infectious anemia virus and immune response and mechanism to Newcastle disease vaccine immunity 论文作者郑世民导师刘忠贵教授学科专业基础兽医学研究领域\研究方向学位级别博士学位授予单位东北农业大学学位授予日期2002 论文页码总数105页关键词鸡传染性贫血病雏鸡新城疫疫苗馆藏号BSLW /2003 /S858 /9 本项研究采用免疫组织化学、免疫胶体金及免疫酶方法,首次对CIAV感染1日龄雏鸡和CIAV感染雏鸡ND疫苗免疫及vNDV攻击后,其外周血液的T细胞、B细胞数量和IgG、IgM、IgA含量;中枢免疫器官胸腺和法氏囊,外周免疫器官脾脏及呼吸道和消化道局部粘膜免疫组织哈德尔腺和盲肠扁桃体的ANAE〓、CD4〓、CD〓T细胞、IgG、IgM、IgA抗体生成细胞数量和CD〓与CD〓T细胞比值以及泪液、气管液、肠液、胆汁的IgA、IgM、IgG含量的动态变化规律和CIAV感染对ND疫苗的免疫保护率等进行了全面系统地研究。

Results a total of7924people from15survey sites of6counties were under fecal examination,the overall infection rate of intestinal helminthes was59.40%.of the discovered16parasite species,11were nematodes,2taeniae and3trematodes.the infection rate of hook worm,trichuris and ascaris were33.18%、31.35%and14.29%,respectively.the mixed infection was serious.the infection rate were higher in age groups of5~9years and10~14years;nationality-based analysis showed infection rates in hans,lis,miaos and huis being48.27%,64.14%,76.36%,and58.96%,respectively;the infection rate in female was higher than that in male.

结果 整群随机抽样全省5个市、县15个点7924人,调查发现人群肠道蠕虫感染率为59.40%,其中土源性线虫感染率为56.22%,查见肠道蠕虫16种,其中线虫11种,绦虫2种,吸虫3种,感染率较高的虫种是钩虫、鞭虫和蛔虫,其感染率分别为33.18%、31.35%和14.29%;多虫感染较严重,感染度以轻度感染为主,感染年龄以5~9岁和10~14岁两组为高;汉、黎、苗、回各民族感染率分率别为48.27%、64.14%、76.36%、58.96%;女性和农村居民感染率明显高于男性和城镇居民。

Observation with transmission electron microscope showed that interalveolar septa were widened with increased amount of collagen in the MP infected rats while there were no obvious abnormalities in the other two groups.(2) Positive expression of bFGF mRNA were found in alveolar walls of MP infected rats. No expression of bFGF mRNA was found in control animals. In the rats infected with MP but treated with erythromycin positive expression of bFGF mRNA was found to be scarcely distributed in alveolar walls.

2感染组动物肺泡壁见明显的bFGF mRNA阳性表达颗粒,对照组基本未见bFGF mRNA阳性表达,感染加红霉素治疗组仅见散在分布的少许bFGF mRNA阳性表达;定量分析结果表明,感染组bFGF mRNA阳性表达的积分吸光度为41.32±10.44,与对照组(0.30±0.13)和感染加红霉素治疗组(6.03±2.41)比较,差异有显著性( P <0.01)。

In this study,we investigate the efficacy and safety of intraocular use of fluconazole in the treatment of ocular fungal infection. Ten patients with intraocular fungal infections were examined. Among these patients , eight were infected with keratomycosis with intraocular spreading, one had postoperative fungal endophthalmitis after cataract operation with an intraocular lens implant, and another suffered from endogenous fungal endophthalmitis.

为探讨眼球内注射fluconazole用於治疗眼球内霉菌感染之效果以及安全性;我们搜集十位眼球内霉菌感染的病人,其中包括八位严重角膜霉菌感染;两位为霉性眼内炎,这些病人在传统治疗无法有效控制感染后,都曾接受眼球内注射fluconazole的治疗,包括前房灌洗、前房内注射或玻璃体内注射,使用浓度为5-10g/ml。

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