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The first task of Cornus study is to explore further uses of its active components, improve the level of its quality control and establish an internationally recognized method for quality control.

进一步加强山茱萸药材中有效成分的开发和利用,提高其质量控制水平,建立国际公认的质量控制手段,是当前对于山茱萸药材研究的首要任务。

ObjectiveTo study the technological parameters of purification of total glycoside from Cornus officinalis with macroporous resin.

目的应用大孔吸附树脂对山茱萸中环烯醚萜苷类成分进行分离纯化,考察大孔树脂纯化山茱萸总苷的工艺参数。

This RP-HPLC- ELSD method combining with HPLC fingerprints of Cornus established a general quality control standard and provided the ground for good agriculture process and sustainable development of Cornus.

结合指纹图谱的研究以期建立山茱萸药材质量的综合评价方法,为山茱萸规范化种植和药材的可持续发展提供依据。

AIM: To investigate the influence of the cornus officinalis glycosides on immunological function of corneal transplantation model of rats, and to clarify the immunosuppressive mechanism of COG through observing the activation of lymphocytes in blood.

目的:观察山茱萸总甙对大鼠角膜移植模型细胞免疫功能影响,并通过观察外周血淋巴细胞活化状态以期进一步阐明山茱萸总甙的免疫抑制机制。

The petals of the Cornus florida variety have a notch at the tip, while those of the Japanese dogwood, Cornus kousa, come to a point.

花瓣的山茱萸佛羅里達品種有缺口的提示,而日本山茱萸山茱萸照,到了點。

Ursolic acid, which has immunity enhancement in the Cornus, was chosen as primary index in this research. The method of reversed-phase high performance liquid chromatography with ultraviolet detector was developed to determine the content of ursolic acid. The L9(34) orthogonal experimental design was used for Cornus to further process and explore its health product using the content of ursolic acid and the rate of paste as the assessment indexes.

本研究以山茱萸中具有增强免疫功能的熊果酸为主要考察指标,采用反相高效液相色谱-紫外检测法作为熊果酸含量的测定方法,以出膏率为参考指标,采用L9(34)设计正交试验,对山茱萸药材进行了深加工,开发其保健品;对所得到的提取物中的多糖进行了定性鉴定。

The TLC method of ursolic acid and loganin in Cornus chinense Wanger and its kindred plant were respectively seted up.

2川鄂山茱萸果实解剖学特征可以区别川鄂山茱萸及其近缘植物,以免相似入药部位产生的混淆。

With the "green food" demanding ,it is very necessary to extract ursolic acid from the dogwood acid as active ingredients.

随着人们对"绿色食品"要求的提高,从山茱萸中提取熊果酸等有效成分,对进一步开发山茱萸十分必要。

In the light of looking up -finishing-inquiring into the literature,The subject ntegratedly applied the knowledge of botany and phytotomy and Authentication of Chinese Medicines and the experimental technology to study taxonomy and anatomy of Cornus chinense Wanger and its kindred plant.To combine the knowledge of natural medicinal chemistry instrumental analysis,pharmaceutical analysis and experimental technique,Glycosides chemical components of Cornus chinense Wanger and its kindred plant were qualitatively analysised by using TLC.

以文献查阅-整理-调查为基础,综合运用植物学、植物解剖学、中药鉴定学知识与实验技术对川鄂山茱萸及其近缘植物进行分类学处理与解剖学研究,结合天然药物化学、仪器分析、药物分析等学科的知识与实验技术,用TLC定性分析川鄂山茱萸及其近缘植物的苷类化学组分;用HPLC测定川鄂山茱萸不同器官、细胞组织、果实不同采集期的熊果酸、马钱苷的含量并进行色谱条件优化。

Research discover dogwood A has the good protective function to the CCl4 liver damage model and the blood vessel endothelial cell, therefore think that A is in the dogwood an important biological active ingredient, and still discover that the dogwood liquor steamed product A content increase obviously to living product, confirm the steamed system can increase A content; Moreover, discover living product water decoction A content have four times as much as methanol supersonic extraction, but made product difference is not big, this also confirm the heating really has very big influence to A content, but do not further study the dogwood the living product and the liquor steamed product decoction change in body content.

研究发现山茱萸中A对CCl4 肝损伤模型及血管内皮细胞具有良好的保护作用,因此认为A为山茱萸中一重要的生物活性成分,而且还发现山茱萸酒蒸品中A的含量较生品中明显增加,证实了蒸制能增加A的含量;另外,发现生品水煎煮提取物中A的含量也较甲醇超声提取物中的高出约3倍,而制品则差别不大,这也证实了加热对A的含量确有很大的影响,但没进一步研究山茱萸生品与酒蒸品水煎液在体内的含量的变化。

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