局部基

Transmission electron microscopy examination: epithelium cells degeneration, chromatin margination and collagen arrangement disorder could be observed at early stage after bothsided LASIK.

透射电镜下：BSL术后早期上皮细胞轻微变性，少量纤维细胞核染色质边集，角膜瓣边缘局部胶原排列稍紊乱。1mo时基质胶原纤维排列整齐，直径大小一致。

When bromine was used to bromization reaction with 4-acetyl-guaiacol,the product bromide incompletely or super bromide partial,and the selectivity was poor.

使用单质溴与4-乙酰基愈创木酚进行溴化反应时，产物溴化不完全，或者局部过量的溴化，且选择性较差。

Results: A 24-year-old woman suffered from acute painful sensation of both eyes after putting on contact lenses soaked in hydrogen peroxide care solution. Bilateral punctate corneal epithelial erosions were diagnosed. To relieve pain, she, by herself, applied topical 0.5% proparacaine eye drops to both eyes with increasing frequency to almost hourly. However, the pain was aggravated. On examination 2 days later, a large central disciform epithelial defect and diffuse edema of the residual epithelium were noted in both corneas. With the treatment using non-preserved artificial tears, the epithelial defects started to heal the next day and ring-shaped stromal cellular infiltrates were observed at the border of previous epithelial defects.

病例报告结果：一位24岁年轻女性因为配戴曾浸泡於含双氧保养液之隐形眼镜，造成双眼角膜点状上皮缺损，为了减少疼痛几乎每一小时双眼使用0.5%丙美卡因局部麻醉眼药水，然而疼痛恶化，并且在两天之后产生双眼角膜中央盘状上皮缺损，在使用不含防腐剂之人工泪液药水后，第二天表皮开始逐渐愈合，可以发现在原本上皮缺损边缘出现环状基质细胞浸润。

In this paper, we define quadratic spline as wavelet, do the two dimentional dyadic wavelet transform on near-infrared galactophore image, and get local modulus maxima from wavelet transforms results----rnodulus and angles, so we can find the blood vessel edge image in each scales, at last, we compute a good edge image which synthesize the characters in each scale.

本文中用二次样条小波作为小波基函数，对乳腺近红外图像进行二维二进小波变换，计算小波变换结果的局部模极大值点，得到各个尺度下的乳腺近红外图像血管的边缘，最后得到综合了各个尺度特征的较好的血管图像的边缘。

Hygrophilous species disappeared partly, and disturbance-resistant species and exotic species expanded their populations in the tourism area;(2) the community structure of bryophytes on the fir trunks in the tourism area was found simpler than that in the undisturbed area; and (3) the trunk at height of 120~180cm was more susceptible to disturbance, but the base was not affected signif icantly by disturbance.

在旅游活动频繁地段，耐荫喜湿物种局部消失，耐干旱抗干扰的植物种群扩大；(2)旅游活动频繁地段树干附生苔藓植物的丰富度、盖度和生物量较未扰动地段小；(3)距地面较高的高度120cm和180cm处受到的干扰强度最大，基部的影响较小。

Areas of focus include the nervous system and hippocampal neurogenesis, along with the functional significance of pro-inflammatory cytokines, and the freeduan.com production of free radicals after brain ischemia; the digestive and integumentary systems, dealing with hepatocyte transplantation, pancreatic regeneration, and skin and hair regeneration; and the cardiovascular system, with repair and remodeling of the lung and heart, and arterial remodeling with bone marrow-derived progenitor cells.

焦点的地区包括神经系统和hippocampal neurogenesis，跟支持煽动性的cytokines的功能的意义，以及在大脑局部缺血之后自由基的freeduan.com生产一起；消化药和integumentary系统，处理hepatocyte移植，胰的再生和皮和头发再生；并且心血管系统，有修理和肺和心脏，和动脉与骨髓得到祖先细胞一起改塑的改塑。

Gene-activated matrix technology is a non-viral gene therapy strategy. Though with less impressive gene transfer efficiency than viral gene therapy, it has been used to deliver osteogenic factors locally and promote bone regeneration in long bones. The minimal safety concerns of GAM support its use in non-life-threatening conditions such as craniofacial osseous defects. However, the uses of GAM technology in intramembranous bone are largely unexplored.

活化基因基质技术是一种非病毒性的基因疗法，虽基因转移之效率一般不如病毒性基因疗法，但曾被用来局部产生骨生成因子而促进长骨缺损骨再生，其安全性高，应适於治疗颅颜骨缺损等不具生命危险性的状况，惟至今在膜内骨之相关研究仍甚少。

Brane, such as synoviocytes, macrophages, osteoclasts and TNF-αvv acts on different kinds of cell in synovial memchondrocytes, which can produce metalloproteinase,collagenase, stromelysin and so on, further induce pannus formation, joint inflammation, bone erosion and cartilage degradation.

TNF-α可作用于RA关节组织中的滑膜细胞、巨噬细胞、软骨细胞和破骨细胞，使这些细胞活化，产生金属蛋白酶、胶原酶、基膜溶解酶等，导致局部炎症反应和血管翳形成，进一步引起软骨破坏和骨侵蚀。

Both Fas and NO can lead chondrocyte apoptosis respectively and cause articular cartilage destruction. IGF-Ⅰ, TGF-β, bFGF, BMP and other growth factors are polypeptide agents that can influence cell activity by signal convection. They can accelerate chondrocyte proliferation and proteoglycan synthesis, play the local regulation action on formation and plerosis of bone and cartilage tissue by autocrine or paracrine. They have the ability to induce cartilage formation. Some investigations showed that growth factors can influence chondrocyte metabolism, synthesis of specific Ⅱ type collagen and proteoglycan by co-operation and inhibition. 1. 3 Situation of OA therapeutics The therapeutic methods of OA mainly comprised non-drug treatment, drug treatment, operation treatment, tissue and genetic engineering, et al. Drug treatment is the chief method among them.

若其活性发生改变，则将导致关节软骨基质成分的丢失和进行性破坏；软骨细胞凋亡与OA的发病密切相关，Fas与NO可各自独立介导软骨细胞凋亡，造成关节软骨破坏；IGF-Ⅰ、TGF-β、bFGF、BMP等生长因子是一组通过细胞间信号传递影响细胞活动的多肽因子，具有促进细胞生长、增殖与合成等作用，可通过自分泌或旁分泌方式对骨和软骨的形成和修复起局部调节作用，可促进软骨细胞增殖、分化与蛋白多糖的合成，具有较强的诱导软骨形成的能力，研究表明多种生长因子相互促进、相互抑制，以协同或拮抗方式影响软骨细胞代谢，影响软骨细胞特异性Ⅱ型胶原和蛋白多糖的合成分泌。

Signalling through CXCR4 mediates actin polymerization and pseudopodia formation in cells, and induces chemotactic and migration to target organs. In addition, CXCR4-SDF-1 axis can promote tumor angiogenesis and growth.

CXCR4在肿瘤组织中的表达明显高于正常组织，而肿瘤常见转移部位均为CXCR4的配体基质细胞衍生因子-1(stromal cell derived factor-1，SDF-1)表达丰富的器官，SDF-1与CXCR4结合后可使细胞肌动蛋白丝聚合，形成伪足，从而定向诱导肿瘤细胞迁移到特定的靶器官；此外，CXCR4与其配体SDF-1相互作用可以促进局部新生血管作用，利于肿瘤生长。

Cynanchum Lingtai apricot production in the average weight 65 grams, the brightly-colored fruit, juicy rich, sweet-sour taste, sweet from the nucleolus, when the late Qing Dynasty famous Shaanxi, Gansu provinces, the Qing imperial court Tongzhi tribute for years.

灵台生产的牛心杏平均单果重65克，果实色泽鲜艳，汁多味浓，甜酸适口，离核仁甜，清末时就驰名陕、甘两省，清同治年间曾为朝廷贡品。

Chenopodium album,Solanum nigrum, and Amaranthus retroflexus were very susceptible to the herbicides. Polygonum persicaria and Abutilon theophrasti were relatively less susceptible to the herbicides, and Lycopersicon esculentum was not susceptible to it. The relationship between reduction rates of weed biomass and PPM values of weed leaves 2,4, and 6 days after treatment was established.

供试的6种杂草对该混剂的敏感性存在显著差异：红心藜Chenopodium album、龙葵Solanum nigrum和反枝苋Amaranthus retroflexus对该混剂最敏感，ED90值分别为47.65、71.67和29.17g/hm2；春蓼Polygonum persicaria和苘麻Abutilon theophrasti敏感，ED90值分别为96.91、114.20g/hm2；而番茄不敏感。