小血小板

Results In those patients with marrow invasion , 4 cases in I phase（4.2%）,12 cases in II phase（12.6%）,36 cases in Ⅲ phase（37.9%）and 43 cases in Ⅳ phase(47.4%);small lymphocytic、diffuse cleaved cell、lymphoblastic lymphoma are main pathologic types;patients with mediastinal lymphadenectasis、splenomegaly and spleen violations are prone to catch bone marrow involvement;56 cases of anemia in patients with bone marrow involuement(58.9%), 42 patients with thrombocytopenia (44.2%),27 cases with leukopenia (28.4%),49 cases of patients leukocyte increased (51.6%),so,anemia is common;three were 30 cases with three items abnormal（31.6％）and 65 cases with one item abnormal at least (68.4%),the incidence of abnormal peripheral blood in leukocythemia patients were higher than that in patients with bone marrow infiltration,Particularly the patients with increased leukocyte or three items abnormalities were more common in leukemia; Abnormal cells in peripheral blood were observed in 66 cases (69.5%); chemotherapy efficiency reached 65.2% in the patients with bone marrow involuement,the median survival time was 11.5 months.

结果发生骨髓侵犯病例中I期4例（4.2%）， II期12例（12.6%），Ⅲ期36例（37.9%），Ⅳ期43例(47.4%)；病理类型以小淋巴细胞性，弥漫型裂细胞性（改为：弥漫性大B细胞型淋巴瘤）和淋巴母细胞性淋巴瘤多见；纵隔淋巴结肿大、脾脏肿大和脾受侵患者易发生骨髓侵犯；骨髓侵犯患者外周血中贫血56例(58.9%)，血小板减少42例(44.2%)，白细胞减少27例(28.4%)，白细胞增高49例(51.6%)，以贫血多见；三项均异常30例(31.6%)，至少一项不正常65例(68.4%)，淋巴瘤细胞白血病患者外周血象异常发生率高于骨髓浸润患者，尤其是白细胞增高或三项均异常者更常见于白血病；66例(69.5%)外周血分类中发现异常细胞；骨髓侵犯化疗有效率65.2%，中位生存期11.5个月。

Results True positive rate: immature granulocyte, hemoglobin concentration variation, microcyte, left shift, macrocyte, hypochromic erythrocyte, large platelet, blasts, anisocytosis 86.7%-100.0%, hyperchromic erythrocyte 69.2%, nucleated red blood cell, atypical lymphocyte, platelet clumps

结果 真阳性率：未成熟粒细胞、血红蛋白浓度不等、小红细胞、核左移、大红细胞、低色素性红细胞、大血小板、原幼细胞、红细胞大小不等为86.7%~100.0%，高色素性红细胞为69.2%，有核红细胞、变异淋巴细胞、血小板凝集为13.3%~32.3%；以上所有参数真阴性率为82.8%~100.0%（平均95.0%）。

HSP is the most common blood vessel inflammation disease in childhood, its main clinical manifestations are nonthrombocyte reducing purpura, arthritis or arthralgia, bellyache, gastroenterostomy haemorrhage and nephritis, and its main pathological characteristics are general small blood vessel inflammation surrounded by neutrophils and eosinophils.

过敏性紫癜是儿童时期最常见的血管炎之一，以非血小板减少性紫癜、关节炎或关节痛、腹痛、胃肠道出血及肾炎为主要临床表现。主要病理变化为全身性小血管炎，小血管周围可见中性粒细胞及嗜酸性粒细胞浸润。

Results Erythrocyte count, hemoglobin concentration and hematocrit of all the patients with malignant digestive tumor decreased, mean corpuscular volume and mean corpuscular hemoglobin increased, arid there was inconspicuous change in total leukocyte count. The indications of megaloblastic anemia and proliferative anemia in bone marrow hemogram were found in the patients. It was common that the percentage of neutrophils was higher and that of lymphocytes was lower than that of the normal controls.

结果 消化道恶性肿瘤患者的红细胞计数、血红蛋白、红细胞压积均减少，平均红细胞体积、平均红细胞血红蛋白量增高，均表现为巨幼细胞性贫血，骨髓象呈增生性贫血改变，而白细胞总数的变化较小，白细胞分类，中性粒细胞百分比超过正常范围与淋巴细胞百分比低于正常范围者多见，血小板数异常远较血红蛋白与白细胞为少，但36例肝癌患者中28例出现血小板减少。

There is controversy as to whether prophylactic platelet transfusions are necessary or beneficial, although it seems that maintaining a platelet count of greater than 5,000, and sometimes higher, reduces the risk of minor bleeding (e.g., nose bleeds, bruises in the skin called ecchymoses, pinpoint bleeding in the skin called petechiae).

虽然把血小板计数维持在5000以上似乎能够减少小出血的风险（比如，流鼻血，皮肤的瘀斑以及小瘀点），但是人们对于预防性输注血小板的必要性及好处仍存有分歧。

There is controversy as to whether prophylactic platelet transfusions are necessary or beneficial, although it seems that maintaining a platelet count of greater than 5,000, and sometimes higher, reduces the risk of minor bleeding (e.g., nose bleeds, bruises in the skin called ecchymoses, pinpoint bleeding in the skin called petechiae).

虽然把血小板计数维持在5000以上似乎能够减少小出血的风险（比如，流鼻血，皮肤的瘀青以及小瘀点），但是人们对于预防性输注血小板的必要性及好处仍存有分歧。

There is controversy as to whether prophylactic platelet transfusions are necessary or beneficial, although it seems that maintaining a platelet count of greater than 5,000, and sometimes higher, reduces the risk of minor bleeding (e.g., nose bleeds, bruises in the skin called ecchymoses, pinpoint bleeding in the skin called petechiae).

虽然使血小板计数维持在5000以上似乎能够减少轻微出血的风险（比如，流鼻血、皮肤的瘀斑及小瘀点），但是人们对于预防性输注血小板的必要性及好处仍存有分歧。

Topotecan is an effective agent for SCLC when used as monotherapy or in combined treatment, but myelosuppression such as leucopenia and thrombopenia was relatively severe. Although it has been recommended as a second-line agent for recurrence of sensitive SCLC, more clinical trials are needed to define its role in first-line treatment.

拓扑替康治疗小细胞肺癌有确切临床疗效，无论是单药还是与其他药物的联合用药均具有与当前一线经典方案相当的疗效，但具有相对高的致白细胞和血小板下降的骨髓毒性，已被认为是治疗化疗敏感的小细胞肺癌患者复发的二线推荐药物，但是作为一线用药仍然需要更多的实践来证实。

Conclutions Topotecan is an effective remedy for treatment of small cell lung cancer, both single topotecan and combined regimen has the same effect as the traditional first-line regimen, though myelo-suppression such as leucopenia and thrombopenia is more sever, the adverse effect is tolerated. Though it has been recommended as second-line agent for chemo-therapy sensitive small cell lung cancer, there needs more clinical studies to verify its role in first-line.

结论拓扑替康是在小细胞肺癌的治疗中有确切临床疗效的药物，无论是单药还是与其他药物的联合用药均具有与当前一线经典方案相当的疗效，虽具有相对高的致白细胞和血小板下降的骨髓毒性，但毒副作用可耐受，已经被认为是治疗对化疗敏感的小细胞肺癌患者的二线推荐药物，但是作为一线用药仍然需要更多的临床证据来证实。

Results:The results of these 2 methods were(66±17)×109/L and(98 ±2 0)×109/L,their difference was significant(P＜0.001).Their influential f actors were large platelets,platelet clumps,cryoglobulins and schistocytes besid es microcytes.

结果：仪器法结果为(66±17)×109/L，而显微镜计数法为(98±20)×10 9/L，两法结果差异有显著性(P＜0.001)；URI报警时除小红细胞干扰外，还有其他诸多因素；大血小板、血小板凝集块、冷球蛋白、衰老破坏的红细胞碎片等，其中最常见的为大血小板。

Cynanchum Lingtai apricot production in the average weight 65 grams, the brightly-colored fruit, juicy rich, sweet-sour taste, sweet from the nucleolus, when the late Qing Dynasty famous Shaanxi, Gansu provinces, the Qing imperial court Tongzhi tribute for years.

灵台生产的牛心杏平均单果重65克，果实色泽鲜艳，汁多味浓，甜酸适口，离核仁甜，清末时就驰名陕、甘两省，清同治年间曾为朝廷贡品。

Chenopodium album,Solanum nigrum, and Amaranthus retroflexus were very susceptible to the herbicides. Polygonum persicaria and Abutilon theophrasti were relatively less susceptible to the herbicides, and Lycopersicon esculentum was not susceptible to it. The relationship between reduction rates of weed biomass and PPM values of weed leaves 2,4, and 6 days after treatment was established.

供试的6种杂草对该混剂的敏感性存在显著差异：红心藜Chenopodium album、龙葵Solanum nigrum和反枝苋Amaranthus retroflexus对该混剂最敏感，ED90值分别为47.65、71.67和29.17g/hm2；春蓼Polygonum persicaria和苘麻Abutilon theophrasti敏感，ED90值分别为96.91、114.20g/hm2；而番茄不敏感。