家系

The ancestry of the piano can be traced to the early keyboard instruments of the fifteenth and sixteenth centuries --- the spinet, the dulcimer, and the virginal.

钢琴钢琴的家系可以追溯至15至16世纪早期的键盘乐器，包括小型拨弦琴、洋琴和维金娜琴。17

Gene mutations were detected in 25 patients and a 18-year-old girl among 16 families. Trinucleotide repeats of CAG were 73～79. The fragments of abnormal alleles were 380～402bp, and all patients were heterozygous. The copy numbers of normal alleles were 18～40, fragments from 202～270bp. SCV reduction was much obvious compared to MCV, MCV and SCV in lower limb ?ere much more slow than that in upper's. BAEP, VEP were also delayed in latency. The anticipation in parental sex bias were much more obvioius than that in matental's. Cerebellar ataxia was most severe, the next were dysarthria and bulging eyes. Amytrophy was seen only in bed ridden patients. Cerebellar atrophy was more severe than brain stem, cord atrophy was n't observed in all MJD.

结果检出10个家系25例病人及1例症状前18岁女孩有MJD基因突变，CAG三核苷酸重复73～79次，异常等位基因片段长380～402bp，均为杂合子；正常人CAG三核苷酸重复18～40次，等位片段长200～270bp，电生理发现MJD的SCV减慢比MCV明显，而下肢的MCV、SCV又较上肢明显，BAEP、VEP均有不同程度的潜伏期延长或波的异常；MJD的父亲遗传早于母亲，进展也较块，临床以小脑性共济失调为突出症状，其次为构音障碍、突眼等，肌肉萎缩仅见于晚期病人；MRI示小脑萎缩较明显，脑干萎缩并不严重，未见明显的颈髓萎缩。

Results: A family with progressive muscular dystrophy was obtained. There were 12 cases in 4 generations in this family.

结果得到一进行性肌营养不良家系，4代41位成员中有12例患者。

The mutation of G2034R is the underlying cause of epidermolysis bullosa pruriginosa in this family, not common polymorphism.

G2034R突变是引起该家系临床病变的特异突变，不是多态性变化。

The splicing mutation of COL7A1 gene is the underlyi ng cause of and specific rather than common polymorphism for the family with dys trophic epidermolysis bullosa pruriginosa subtype.

结论COL7A1基因剪接位点的突变是引起该家系临床症状的特异突变，而非多态性改变。

Objective To identify gene mutation of a epidermolysis bullosa pruriginosa family. Methods Polymerase chain reaction, DNA squencing, multiplex PCR using allele-specific oligonucleotide primers.

采用聚合酶链反应，DNA直接测序以及等位基因特异引物的多重PCR方法，对一个痒疹样大疱性表皮松解症家系40人（其中患者23例）进行基因突变情况检测。

In study of equational data on bipolar disorders, the application of linkage analysis was limited, but the results of else three statistical models were similar. They all suggested that the relation between DRD2P or COMT and bipolar disorders had no significance.

在平衡数据的双相情感性精神障碍家系资料致病基因位点的研究中，连锁分析的应用受到限制，而其它三种统计模型的结果一致，DRD2P和COMT基因位点与疾病的关系均无统计学意义，但随着样本含量的增大，广义估计方程表现了一定的优势。

It was concluded that the stemma equimultiple random select cross method could constrain the increments of inbreeding coefficient.

采用家系等量随机选配法保存鸡种，可有效地控制保种群近交系数的增长。

The affected members of the kindred exhibited erythrocytosis.

该家系有7名成员为这种异常血红蛋白的杂合子，并且都表现出红细胞增多症。

The culm length, panicle length, spikelets per panicle and panicle exsertion were evaluated by using F2:3 population including 200 lines, derived from a cross of indica and japonica Milyang23/Jileng1 under five different environments of Beijing (natural normal growing environment), Kunming (natural low temperature condition), Gongzhuling of China and Chuncheon of Korea (natural normal growing environment and cold water irrigation), and QTLs of these traits were analysed by using SSR markers.

以籼粳交密阳23/吉冷1号200个F2：3家系作为作图群体，在北京、昆明、公主岭、韩国春川（正常生长环境和冷水胁迫）等5种不同生长环境下进行了水稻秆长、穗长、穗粒数和穗抽出度等主要农艺性状的异地鉴定，并利用SSR标记进行了上述农艺性状的QTL分析。

What are your goals and strategies for growth?

你的成长目标和策略是什么？

And unto the angel of the church in Sardis write; These things saith he that hath the seven irits of God, and the seven star I know thy works, that thou hast a name that thou livest, and art dead.

3：1 你要写信给撒狄教会的使者，说，那有神的七灵和七星的，说，我知道你的行为，按名你是活的，其实是死的。