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The significant correlation existed in the total litter, number of ablactation pigs and litter weight after ablactation.

其中DD和BB基因型的个体上述生产性能显著高于BB和AA基因型的个体,也高于BD和AB基因型的个体,但差异不显著。

The method of Agrobacterium-mediated transformation is the most widely used in genetic transformation. To this day, only several genotypes such as Bobwhite and Yangmai158 have been used in transformation successfully. To widen the recipient genotypes, ten different genotypes were transformated by Agrobacterium-mediated In our study, transformation efficiency of B31706 and B31575 were significantly higher than Bobwhite. Moreover, regeneration rate and resistant plantlet rate of Agrobacterium-mediated genetic transformation in B31706 immature embryos callus was the highest one among the genotypes.

农杆菌介导法是目前应用较为广泛的转化方法之一,但在小麦中,只有包括Bobwhite和扬麦158在内的少数几个基因型被成功用于农杆菌介导的小麦遗传转化中,为了拓宽小麦农杆菌转化的受体基因型范围,本研究对10个不同基因型的材料进行了转化实验。B31706和B31575的转化率明显高于对照材料Bobwhite 。

To identify additional epidermolysis bullosa simplex mutations for studying the correlation between genotype and phenotype of EBS, and to provide basis for genetic counselling, as well as for gene diagnosis and gene therapy..

目的鉴定更多的单纯型大疱性表皮松解症突变以研究EBS基因型和表型关系,为EBS的遗传咨询及基因诊断和基因治疗奠定基础。

Objective To identify additional epidermolysis bullosa simplex mutations for studying the correlation between genotype and phenotype of EBS, and to provide basis for genetic counselling, as well as for gene diagnosis and gene therapy..

目的鉴定更多的单纯型大疱性表皮松解症突变以研究EBS基因型和表型关系,为EBS的遗传咨询及基因诊断和基因治疗奠定基础。

The phylogenetic analysis showed that QH3,HLJ and A4 belonged to the genetype Ⅷ,Ⅸ,Ⅵ respectively. It indicated that not only NDV genetypes among epizootic strains isolated from different areas were evidently variable, but also special genetype DC which hadnt prevailed in abroad was present in China.

表明我国NDV流行毒株在各地区之间具有明显的基因型差异,而且还具有不同于国外流行的我国特有的基因型——基因Ⅸ型。

To study genetic mutations of methylenetetrahydrofolate reductase C677T and cystathioinine-β-synthase T833C related to homocysteine metabolism in patients with ischemic stroke, the MTHFR gene C677T gene mutation and the CBS T833C gene mutation were detected by PCR-RFLP or ARMS method in 74 patients with ischemic stroke and 83 normal people for control. Results showed that the frequencies of MTHFR genet homogenetic type(2.7%), heterogenetic type(51.4%) and T allele(28.4%) in ischemic group were higher than those in control group(1.2%, 39.8% and 21.1%, respectively).

为研究同型半胱氨酸代谢相关酶亚甲基四氢叶酸还原酶基因C677T和胱硫醚-β合成酶基因T833C位点碱基突变与缺血性脑卒中的关系,对74例缺血性脑卒中患者和83例健康对照者,采用聚合酶链反应-限制性片段长度多态性技术检测MTHFR基因C677T基因型,用扩增阻滞突变体系法检测CBS基因T833C突变。

Results:(1) totally, the distributions of alleles o r genotypes of drd3 ser9gly polymorphism are not significantly different between the groups of paren ts, unaffected-siblings and affected-siblings, and between the sub-types of schi zophrenia.

结果: (1)总体而言,drd3基因的ser9gly等位基因频度和基因型频度在父母组、非患病同胞组和患病同胞组之间差异无显著性,在精神分裂症不同亚型之间基因型频度和等位基因频度的分布差异也没有统计学意义。

Assume that individuals with the same major gene genotype in a segregating generation are normally distributed due to the variations of polygenes and environment, and individuals with different major gene genotypes follow a mixture of normals with different means and the same variance.

假定分离世代中的同一主基因基因型因多基因和环境的变异而呈正态分布,不同主基因基因型则为具不同平均数和相同方差的混合正态分布。

We put emphosis on the establishment of standard protocol,testing strategy and methods in the study,in addition to the analysis of the positive ratio of GJB2,SLC26A4,mtDNA 1494/1555 in groups of different phenotypes, analysis of genotype,phenotype and its relationship of GJB2 and SLC26A4,drawing the audiograms of GJB2 and SLC26A4 related hearing impairment.Finally,some practical problems that we may come into in genetic testing are discussed.

其中,着重论述临床耳聋基因诊断的规范化流程,以及检测内容、策略和方法,分析GJB2、SLC26A4、线粒体DNA 1494/1555突变在不同受检者群体中的阳性检出率情况,分析GJB2基因和大前庭水管综合征相关SLC26A4基因的基因型和表型以及它们之间的关系,绘制GJB2相关耳聋和EVAS的听力曲线模型,并讨论在临床耳聋基因诊断过程中需要注意的一些具体问题。

The results were as follows. In the insert mutation genotypes, there was significant difference between body weights of 2 weeks aged BB and AB genotype (P.05), while there was no significant difference between AA and other genotypes. In the mutation genotypes, there was no significant difference in body weight. Insert mutation loci had no significant effect on fossil bone length and shank length of 0-12 weeks aged chickens, only mutation loci had a significant effect on fossil bone length and shank length of 6 weeks aged chickens.

分析多态位点与0-12周龄鸡生长发育性状的关联性,结果表明:插入突变基因型中,2周龄鸡体重BB型与AB型差异显著(P.05),但AA型与AB型和BB型差异均不显著,而突变各基因型间没有显著差异;插入突变位点对0-12周龄鸡的龙骨长、胫骨长均没有显著影响,而突变位点仅在鸡6周龄时表现出与龙骨长、胫骨长间的差异显著性。

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