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The human CTLA-4 gene, which lies on 2q33, has four exons: exon 1 encodes leader sequence, exon2 encodes 116 Aa forming extra-cellular V-like functional domain, exon 3 encodes 37 Aa of hydrophobic membrane domain and exon 4 encodes 34 Aa of cytoplast domain.

人类的CTLA-4基因位于2q33,有四个外显子组成,其中第一外显子编码前导序列,第二外显子编码116个氨基酸组成的胞外功能区,第三外显子编码37个氨基酸组成的疏水性跨膜区,第四外显子编码34个氨基酸组成的胞内区。

These dendritic NOBIN derived Schiff base ligands have been applied to titanium catalyzed hetero-Diels-Alder reaction of Danishefshy's diene and aldehydes, affording the corresponding 2-substituted 2, 3-dihydro-4H-pyran-4-one in quantitative yields and excellent enantioselectivities (up to 97. 2%ee). Comparing the reactivities and enantioselectivities of reaction catalyzed by the titanium complexes of these Schiff base ligands, it was found that a series of ligands L〓 were superior to the other three series of ligands L〓, L〓 and L〓, a significant positive NLE and a dendrimer effect existed in the L〓 dendritic catalyst system. The disposition of the dendritic wedges and the dendron size in the ligands were observed to have a significant impact on the enantioselectivity of the reaction.

NOBIN衍生的树枝状大分子希夫碱手性配体与钛形成的配合物在催化不对称杂Diels-Alder反应中的应用将得到的四个系列NOBIN衍生的树枝状希夫碱三齿手性配体与四异丙氧基钛形成的配合物用于催化Danishefsky's diene与醛的不对称杂Diels-Alder反应,通过反应条件的优化,获得了定量的收率和最高达97.2%ee值的对映选择性;考察了这四个系列NOBIN衍生的树枝状希夫碱钛配合物的催化活性和对映选择性,结果发现它们的活性次序依次为L〓≈L〓>L〓>L〓,对映选择性次序依次为L〓>L〓>L〓>L〓。

Announcing the gamingplatform quad FX on the base of two dual cores processors athlon of 64 FX-7x, company attempted to give although some answer to the series four core processor solutions intel, since its microprocessors with four core AMD will be releasednot beforethe middle of present year.

宣布游戏平台四效果在此基础上两个双核心处理器的Athlon 64的FX - 7x ,公司试图给,虽然有些答案的一系列四个核心处理器解决方案,英特尔,因为它的微处理器与四核心AMD将被释放不beforethe中目前的一年。

For this, 4 link should have held in cadre assessment: Want to build lieutenancy target system of job responsibility; 2 want mutiple level all-around assessment gain; 3 should accomplish 4 height to be in charge of; 4 should apply assessment result correctly, produce earnest and decisive assessment effectiveness.

为此,在干部考核中应把握好四个环节:一要建立任期目标责任制;二要多层次全方位考核实绩;三要做到四个高度负责;四要正确运用考核结果,产生严肃果断的考核效力。

And then bring up to reform the ERP system from four aspects to adapt to the demand of ABC cost accounting process design, we(1)divide activity center according to process means、process object、process craft and concentration degrees of geography position,(2)revise production craft flow detailed list,(3) compile resource requirements planning,(4)compile activity input/ output control statement.

其次提出在ERP财务会计模块中构建ABC思想的思路,主要包括建立成本动因与产品、成本、费用之间的联系、设计适当的会计凭证、建立财务系统ABC核算流程;而后提出从四个方面改造ERP系统以适应ABC成本核算流程设计的需要,一是按加工手段、加工对象、加工工艺和地理位置集中程度四个条件划分作业中心、二是对生产工艺流程清单进行修订、三是编制资源需求计划、四是编制作业投入/产出控制报表。

If we look at Jung's quaternity of our being, pictured above, as a terrain , what starts as four territories that are together nobody-but-ourselves, quickly become four battlegrounds.

如果我们看一下上图中荣格所划分上的四类人,即区域,开始时四个区域作为自我而不是其他任何人在一起,然后很快变为四个战场。

When using Swiftmend it is important to note that if one of the tanks is spiked while the Druid is reapplying Lifeblooms, the Druid should then Swiftmend as the third spell, and reapply Rejuvenation with the fourth spell. Likewise if a raid member falls near death during Lifebloom reapplication, the third and fourth spell can be used to place a Rejuvenation on them followed immediately by a Swiftmend.

关于使用迅捷治愈法术,很重要的一点是在等待叠加或刷新生命绽放时关注tank的血量,如果tank受到很严重的伤害,这时循环的第三个法术施放迅捷治愈而第四个法术补回春,同样的,如果一个raid成员在你补生命绽放的过程中濒临死亡,第三个和第四个法术用来上回春并迅捷治愈(老外闭口不提自然迅捷?)。

A method of double third -power spline is used to add more nodes to the surface of a spiral bevel gear .

提出了一种用位移矩阵法精确求解实现四个或五个位置的刚体导引机构的综合,实现了两边架杆四个或五个对应位置的函数机构的综合以及其它一类连杆机构综合的方法。

By comparing the matrix theory over number field,we mainly discussed the quaternion matrix norm theory,the quaternionic determinant,the complex number expression of the quaternion matrix and the quarternion linear matrix equation.

通过对比一般域上矩阵理论,本文主要从四元数矩阵范数理论、四元数矩阵行列式、四元数矩阵的复表示以及四元数线性方程组和线性矩阵方程四个方面阐述了四元数矩阵理论。

Who in her time kicked a general, two colonels, four majors, ten captains,twenty-four lieutenants, forty sergeants,two hundred and twenty privates, and abomb.

在她的一生中,她踢过一个上将,两个上校,四个少校,十个上尉,二十四个士官,二百二十个士兵和一枚炸弹。

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Cynanchum Lingtai apricot production in the average weight 65 grams, the brightly-colored fruit, juicy rich, sweet-sour taste, sweet from the nucleolus, when the late Qing Dynasty famous Shaanxi, Gansu provinces, the Qing imperial court Tongzhi tribute for years.

灵台生产的牛心杏平均单果重65克,果实色泽鲜艳,汁多味浓,甜酸适口,离核仁甜,清末时就驰名陕、甘两省,清同治年间曾为朝廷贡品。

Chenopodium album,Solanum nigrum, and Amaranthus retroflexus were very susceptible to the herbicides. Polygonum persicaria and Abutilon theophrasti were relatively less susceptible to the herbicides, and Lycopersicon esculentum was not susceptible to it. The relationship between reduction rates of weed biomass and PPM values of weed leaves 2,4, and 6 days after treatment was established.

供试的6种杂草对该混剂的敏感性存在显著差异:红心藜Chenopodium album、龙葵Solanum nigrum和反枝苋Amaranthus retroflexus对该混剂最敏感,ED90值分别为47.65、71.67和29.17g/hm2;春蓼Polygonum persicaria和苘麻Abutilon theophrasti敏感,ED90值分别为96.91、114.20g/hm2;而番茄不敏感。

However, I have an idea.

不过,我有个主意。