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Part of the larger constellation of Ursa Major, the bright dipper stars above are named Dubhe, Merak, Phecda, Megrez, Alioth, Mizar/Alcor, and Alkaid. Of course, stars in any given constellation are unlikely to be physically related.

它是大熊星座的一部份,北斗七星最亮的星,由左到右分别命名为天枢、天璇、天玑与天权为魁,玉衡、开阳(Mizar/Alcor)与摇光为杓,合成为斗。

Part of the largerconstellation of Ursa Major, the bright dipper stars above are named Dubhe, Merak, Phecda, Megrez, Alioth,Mizar/Alcor, and Alkaid. Of course, stars in any given constellationare unlikely to be physically related.

它是大熊星座的一部份,北斗七星最亮的星,由左到右分别命名为天枢、天璇、天玑与天权为魁,玉衡、开阳(Mizar/Alcor)与摇光为杓,合成为斗。

2The anterior cutereous branches of the obturator artery penetrate deepfascia of thigh and epimysium of the adductor muscles closing against the lower rami of pubisor at its outer margin.Pudendal-thigh skin flap pedicled on it may be elevated to repairrectovaginal fistula or small skin defects of perineum.As its piercing point is much higher andthe location of pedicle is more fixed because of restriction of pubic rami,it is not suited toreconstruct new vagina.Moreover,it is not appropriate naming the obturator aretry(or themedial femoral circumflex artery)the pudendal-thigh artery.

闭孔动脉前皮支紧邻耻骨下支或于其外侧缘,穿大腿深筋膜和内收肌肌膜浅出,以之为蒂可以形成皮下蒂阴股沟岛状皮瓣,用于阴道直肠瘘或会阴部较小皮肤缺损的修复,但由于闭孔动静脉前皮支浅出点位置较高,并且由于耻骨下支的阻挡和限制,致使血管蒂的位置较为固定,以之为蒂形成的阴股沟皮瓣不适宜用于阴道再造;另外,将闭孔动脉命名为阴股沟动脉,也有欠妥帖。

The isoform hMAM cDNA consisting of 270 bp, was different from the wild type one of 279 bp due to nine continuous base pair missing. Therefore the translational product of the isoform was seen to be lack of three continuous amino acid (-79~-81, VFM) compared with that of the wild type. The homology of the wild type and the isoform are testified to be 96% in both DNA and amino acid sequences.

乳腺癌组织和乳腺癌细胞株中发现两种hMAM cDNA亚型:hMAM和hMAM,长度分别为279和270bp,二者相差9个连续碱基,其翻译产物相差3个连续氨基酸残基(-79~-81,VFM),二者基因和氨基酸序列匹配度均为96%。cDNA片段分别插入原核表达质粒pGEX-KG,构建的质粒命名为pGEX-KG/hMAM和pGEX-KG/hMAM。

Rat glioma cell C6 was infected by the deficiency recombinant retrovirus (named C6TK). The sensitivity of C6TK cells to GCV or ACV increased 450 or 10 times than that of C6 cells respectively. Rat C6 glioma model was successfully built, and SD rats inoculated intracerebrally C6TK cells had normal gliomas. The average survival periods of the rats were about 15 days. However, after treated with ACV, the growth of C6TK tumors obviously regressed, and the survival periods extended to 57.8±8.1 days, especially in rats injected with mixed PA317TK and C6 cells or in situ PA317TK cells, which the tumors nearly disappeared after ACV administration and the survival periods extended to over 120 or 71.4±36.1 days respectively, P<0.001.

结果:构建了带有HSV-tk基因的反转录病毒载体GINaTK,应用脂质体转移方法将GINaTK导入反转录病毒包装细胞PA317,成为产病毒细胞PA317TK,用带有HSV-tk基因的复制缺陷型反转录病毒感染C6细胞,命名为C6TK细胞,对GCV和ACV的敏感性分别高于亲本450倍和10倍;成功地建立了大鼠脑胶质瘤模型,并证实转染细胞C6TK的成瘤效应未改变,存活期约为15天;而经ACV治疗后,含有C6TK细胞的肿瘤生长明显被抑制,大鼠生存期延长为57.8±8.07天,尤其是采用PA317TK细胞混和治疗组和原位治疗组,肿瘤基本消失,大鼠生存期显著延长,混和治疗组存活120天以上,原位治疗组存活至71.4±36.1天。t检验,P值均小于0.001。

Results: GINaTK retroviral vector containing HSV-tk was constructed and transduced into PA317 retrovirus packaging cell by lipofectin (named PA317TK). Rat glioma cell C6 was infected by the deficiency recombinant retrovirus (named C6TK). The sensitivity of C6TK cells to GCV or ACV increased 450 or 10 times than that of C6 cells respectively. Rat C6 glioma model was successfully built, and SD rats inoculated intracerebrally C6TK cells had normal gliomas. The average survival periods of the rats were about 15 days. However, after treated with ACV, the growth of C6TK tumors obviously regressed, and the survival periods extended to 57.8±8.1 days, especially in rats injected with mixed PA317TK and C6 cells or in situ PA317TK cells, which the tumors nearly disappeared after ACV administration and the survival periods extended to over 120 or 71.4±36.1 days respectively, P <0.001.

结果:构建了带有HSV-tk基因的反转录病毒载体GINaTK,应用脂质体转移方法将GINaTK导入反转录病毒包装细胞PA317,成为产病毒细胞PA317TK,用带有HSV-tk基因的复制缺陷型反转录病毒感染C6细胞,命名为C6TK细胞,对GCV和ACV的敏感性分别高于亲本450倍和10倍;成功地建立了大鼠脑胶质瘤模型,并证实转染细胞C6TK的成瘤效应未改变,存活期约为15天;而经ACV治疗后,含有C6TK细胞的肿瘤生长明显被抑制,大鼠生存期延长为57.8±8.07天,尤其是采用PA317TK细胞混和治疗组和原位治疗组,肿瘤基本消失,大鼠生存期显著延长,混和治疗组存活120天以上,原位治疗组存活至71.4±36.1天。t检验,P值均小于0.001。

Strains M110 and M113 isolated from Aedes albopictus and Armigeres durhami, respectively, which were fatal to suckling mice at 4 days after intracerebrally inoculation and had cytopathologic effects on BHK21 cells, showed a positive reaction to dengue antibody and could be amplified Ly using flavivirus primers and dengue type-4 NS1 gene primers and dengue type-4 NS2a gene primers.

结果 从白纹伊蚊和达勒姆阿蚊中各分离到一株病毒,分别命名为M110和M113,这两株病毒对BHK21细胞能产生明显的细胞病变,脑内接种乳鼠4d左右导致乳鼠死亡。该病毒经血凝、血凝抑制和间接免疫荧光试验提示为黄病毒。分别用黄病毒属特异引物、登革4型病毒NS1和NS2a基因片段特异引物进行RT-PCR扩增、序列测定,证实为登革4型病毒。

In 1985, the Government has invested one million yuan to create a new school site in the west side of county road North Gallery, in September 1986 completed the relocation, named "Big County First School" for one of key middle schools in Hebei Province.

同年10月,由于上级取消大城县建置,曾更名为&任丘第三中学&。1962年1月,恢复大城县建置,校名随之改为&河北大城中学&。1985年,政府投资100万元创建新校,校址在县城北廊大路西侧,1986年9月搬迁完毕,命名为&大城县第一中学&,为河北省重点中学之一。

For metabolites of strain SIPI-800, three active compounds were found, named as SIPI-800-1, 2 and 3 respectively, moreover SIPI-800-1 was new compound showing immunosuppressant activity and moderate anti- anaerobic activity; 2 and 3 were isoflavones with estrogenic activity, attracting activity to fungal zoospores, inhibiting alcohol dehydrogenase and aldehyde dehydrogenase I activities.

对SIPI-800菌株的代谢产物研究,分离出3个活性化合物,分别命名为:SIPI-800-1、2和3,其中1化合物为文献没有报道的新化合物,具有免疫抑制活性(1ug/ml浓度抑制NK细胞88.9%的活性)和弱的抗厌氧菌活性;2和3为异黄酮化合物,分别为Daidzein和Genisten的7甲基化衍生物,具有雌激素活性、强吸引真菌游动孢子、抑制乙醇或醛脱氢酶等活性。

Ten alleles sequenced had the same modular structure, starting with a repeat block of Type 3 followed by a block of Type 1 before the central block of Type 3 (313) at 5'end, and starting with a repeat block of Type 4 followed by the central repeat block of Type 3 (43) at 3'end.

另一种为新发现的变异核心序列,暂命名为7型(type 7)。10个等位基因具有相同的模块结构,在5'端表现为:3型一1型--3型(313)排列,在3'端则表现为:4型一3型(43)排列。

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