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We hypothesized that endothelial cells may play an important role in cholesterol efflux from cells by transformating it to oxysterols, which can prevent the lipid aggradation into the tissue under endothelial cells.

如果血管内皮细胞可将过多的胆固醇等脂类物质由细胞内排出,可阻止过多的脂质进一步向内皮下沉积,进而阻止或减缓动脉粥样硬化的发生和发展。

PART ONEInvestigation on Hp CagA+ strain infection condition and pathogenesis risk analyze in patients of carotid atherosclerosisObjective To observate pathological changes of carotid atherosclerosis as well as Hp infection situation, examinate blood fats, blood serum hs-CRP, blood plasma YKL-40, blood serum sCD14, analyze relations between Hp or Hp CagA+ strain and carotid atherosclerosis, and explore possible mechanism of carotid atherosclerosis caused by infection.

然后进行基础动物实验,应用Hp CagA+菌株干预高脂血症大兔,建立Hp CagA+菌株感染致兔颈动脉粥样硬化模型,进行血清Hp抗体、hs-CRP、血浆YKL-40水平检测、斑块内Hp DNA,进一步求证Hp CagA+菌株感染和颈动脉粥样硬化形成的相关性,Hp CagA+菌株感染是否可促进颈动脉粥样硬化的形成,深入探讨其可能机制,以期为颈动脉粥样硬化形成的病因学研究提供实验基础,为临床治疗颈动脉粥样硬化提供新的策略,从而完善其防治模式。

They are complex mixtures of organic compounds, including various gum resin s, fats, or waxes and, in some instances, poisonous compounds, suspended in a watery medium with dissolved salts, sugars, tannins, alkaloids, enzymes, and other substances from which the latex (or natural rubber, the only available rubber until 1926) can be concentrated, coagulated, and vulcanized.

它们是复杂的有机化合物的混合物,含有各种树胶、脂肪或蜡,在某些情况下还含有有毒的化合物,悬浮于溶解有盐、糖、丹宁酸、生物碱、和其它物质的水性介质中,从中可浓缩、凝结和经硬化处理出乳胶(或天然橡胶,是1926年以前唯一可获得的橡胶来源)。

Domenstic and abroad academicians have disclosed the influence mechanism of these factors from different aspects, including the gene polymorphism and gene mutation in genetics, which are a susceptible factor for cardiovascular complication in type 2 diabetes patients; the dysfunction of endotheliocyte, the metabolic disorder of lipid, and dysfunction of vascular smooth muscle, which can lead to the formation of arteriosclerosis;the formation of immune complex,which can also accelerate the destruction of artery paries;the sctivation of protein kinase C and the dysfunction of platelet, which may ultimately result in the formation of thrombus and influence the function of cadiac muscle cells.

其中主要包括:遗传学方面的基因多态性和基因突变,二者均是2型糖尿病合并心血管疾病的一个易感因素,内皮细胞功能障碍、脂质代谢异常及血管平滑肌细胞功能异常均可导致动脉粥样硬化的形成;免疫复合物的形成可加速动脉壁的破坏;蛋白激酶C的激活及血小板功能受损最终导致血栓形成并影响心肌细胞的功能。

FTY720, a Synthetic Sphingosine 1 Phosphate Analogue, Inhibits Deelopment of Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

FTY720,一种合成的鞘氨醇1磷酸盐类似物,可抑制低密度脂蛋白受体缺陷鼠动脉粥样硬化的发展

This yellow fatty streak seen in childhood is not necessarily a precursor of adult atherosclerosis and occurs in populations in which atherosclerosis is uncommon; it is presumably reversible at this stage.

孩童时期便可见到的这种黄色脂纹,并不一定是成年后动脉粥样硬化的先兆,若发生在动脉粥样硬化病不常见的人群中,可能在此阶段是可逆转的病变。

Methods of the invention may include fitting the dental crowns by adjusting or forming them to provide side-specific features, followed by hardening of the hardenable composition.

本发明的方法可以包括通过调整或成形所述牙冠以提供侧面特定外形特征,接着硬化所述可硬化组合物而使所述牙冠合适。

The preformed dental crowns also include a hardenable composition that has sufficient malleability such that the side-generic external shape can be formed into, e.g., a left-side specific or right-side specific adjusted external shape.

该预制牙冠还包括具有足够充分可煅性的可硬化组合物,从而所述侧面通用外形可以被形成为例如左侧特定或右侧特定调整的外形。

Therefore it can be used for surface hardening and hardening of localised areas of metallic parts by "outrunning" the thermal conduction of heat deeper into the part or to surrounding areas.

因此,可颐于表面硬化,和局部地区的金属部分硬化的&没错&的热传导热深入到部分或周边地区。

Not only this, but it is possible that flavonoids also help to stop bad cholesterol from oxidising, which in practice could make it less likely for arteries to fur up.

不仅如此,类黄酮还可能有助于阻止坏胆固醇氧化,这实际上可降低动脉粥样硬化的可能。

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What are your goals and strategies for growth?

你的成长目标和策略是什么?

And unto the angel of the church in Sardis write; These things saith he that hath the seven irits of God, and the seven star I know thy works, that thou hast a name that thou livest, and art dead.

3:1 你要写信给撒狄教会的使者,说,那有神的七灵和七星的,说,我知道你的行为,按名你是活的,其实是死的。

"It is a testament to making sure unemployment compensation is available, making sure we are looking out for people who have lost their jobs," she said.

"这是个实证,证明我们必须确保人们都可以得到失业补偿,确保那些失去工作的人们得到照顾。"