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P16 gene is composed of two intervening sequences and three exons , and encodes p16 protein , which is the inhibiter of CDK4 and CDK6 . They can together prevent phosphorylation deactivation of pRB , and make the cell cycle blocked in G1 stage. P16 gene promoter region has a great of CpG islands , which can be methylated when some adverse factor appears , and so the genetic transcription of p16 can be inhibited , which leads to gene silencing, cell paraplasm, and tumor generate.

抑癌基因p16编码蛋白P16 ,是细胞周期蛋白CDK4和CDK6抑制剂,它阻止pRB磷酸化失活,使细胞周期阻滞于G1期。P16基因启动子区域富含CpG岛,当受到各种有害因素影响时,容易发生甲基化,从而抑制P16基因转录,导致基因沉默,细胞异常增生,导致肿瘤的发生[5]。

How do people make their lives significatively and deathes valuablely.

在短暂的一生中,如何使人活得有意义,死得有价值?

The valence variety on LaCoO 3 surface in various processes of activation sulfurization was investigated.

然而 ,在SO2 存在下,钙钛矿LaCoO3表面的活性中心发生硫酸盐化而使催化剂失活[2 ] 。

In this theory, vitamin C could sop up the radicals, keeping the cancer cell alive despite chemotherapy treatment.

在这一理论,维生素C可以燮的自由基,使肿瘤细胞还活着,尽管化疗治疗。

Then said he unto me, Prophesy unto the wind, prophesy, son of man, and say to the wind, Thus saith the Lord GOD; Come from the four winds, O breath, and breathe upon these slain, that they may live.

37:9 主对我说,人子阿,你要发预言,向风发预言,说主***如此说,气息阿,要从四方而来,吹在这些被杀的人身上,使他们活了。

Then said he unto me, Prophesy unto the wind, prophesy, son of man, and say to the wind, Thus saith the Lord GOD; Come from the four winds, O breath, and breathe upon these slain, that they may live.

37:9 主对我说,人子阿,你要发预言,向风发预言,说主耶和华如此说,气息阿,要从四方而来,吹在这些被杀的人身上,使他们活了。

Methods Selected30patients(60trachoma eyes,30cases totally),using the high frequency discharge of Model FCI-A therapy apparatus,to make inactivation of chlamydia,and then take orally roxithromycin tablets,and dropped0.1%rifampicin eyedrop,and besmeared Chlortetracycline oculentum.

选择门诊病人30例共60只眼,利用FGI-A型沙眼治疗仪的高频放电效应,使衣原体灭活。口服罗红霉素,局部滴0.1%利福平眼药水,涂金霉素眼膏。

When alcohol inactivates AMPK and SIRT1, it allows fat to accumulate.

当酒精失活AMPK和SIRT1的,它使脂肪积聚。

The marvel at the fact that a man in Scandinavia lived for 300 days on only spuds covered with a bit of margarine.

在斯堪地纳维亚,有个人整整300天只吃涂上少许人造黄油的土豆而健康地活着,这个事实使他们感到惊讶。

And made strong prayers to him, saying, My little daughter is near to death: it is my prayer that you will come and put your hands on her, so that she may be made well, and have life.

5:23 再三地求他说,我的小女儿快要死了,求你去按手在她身上,使她痊愈,得以活了。

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What are your goals and strategies for growth?

你的成长目标和策略是什么?

And unto the angel of the church in Sardis write; These things saith he that hath the seven irits of God, and the seven star I know thy works, that thou hast a name that thou livest, and art dead.

3:1 你要写信给撒狄教会的使者,说,那有神的七灵和七星的,说,我知道你的行为,按名你是活的,其实是死的。

"It is a testament to making sure unemployment compensation is available, making sure we are looking out for people who have lost their jobs," she said.

"这是个实证,证明我们必须确保人们都可以得到失业补偿,确保那些失去工作的人们得到照顾。"