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In our study, we found menadione has anticancer potential on human breast adenocarcinoma MDA MB 231 by weather cell cycle arrest, anti proliferation, or apoptosis. Low concentration of menadione (5.8μM) significant inhibited growth curve on breast cancer cells (MDA MB 231) but not breast cells (MCF 10A) by performing MTT and trypan blue cell counting. RT-PCR and western blotting showed menadione increase p21 gene and protein expressions but decrease cyclin E and CDK2 protein expression resulting in cell cycle G0/G1 arrest by flow cytometry.

MTT及生长曲线的实验,发现menadione在低浓度且长时间作用情况下,对在於人类乳腺上皮细胞癌(MDA-MB 231)是有明显的抑制作用,而在正常乳腺细胞(MCF-10A)则没有影响,在分子转录上及蛋白质表现方面也发现低浓度menadione处理24时能使MDA-MB 231诱发p21基因及蛋白表现量增加及cyclin E、CDK2抑制,再经由流式细胞仪分析也发现低浓度 menadione 处理24小时能使MDA-MB 231细胞周期GO/G1比例上升,造成细胞周期停滞,进而抑制细胞生长。

For spontaneous ROS generation, DAB 2.0 did not consistently generate hydrogen peroxide production with increasing dosages over the entire culture period while it was capable of generating superoxide content except during the 12 h of incubation.

结果显示ROS的变化,DAB 2.0 并没有在随著时间与剂量增加的培养周期中,使H2O2产生一致的改变;另外,DAB 2.0 使细胞在培养周期中产生的O2-除了十二小时外,其余则是趋於上升的变化。

A thermal transfer type printer head for transferring ink onto an article by heating ink to send it flying, wherein auxiliary walls are provided in supply passages adjacent to a transfer unit to raise ink liquid levels in the supply passages to thereby prevent running-out of ink in the supply passages.

要約 加热油墨使之飞散并将油墨转移到被转印体上的热转印方式的打印头,在邻接转印部的供给通路内设置辅助壁,使供给通路内的油墨液面上升,以防止供给通路中油墨中断。

In order to decrease the error rate of speech recognition, speaker adaptation techniques are often used to adjust speaker-dependent acoustic models. MLLR (Maximum Likelihood Linear Regression) and MAP are two of the most popular techniques in recent years. MLLR uses the technique of regression trees. It calculates the transform matrix for each leaf node of the tree. This makes it possible to use fewer sentences to decrease the error rate of HMM-based speech recognition. However, while we examined the recognition result, we found that although the overall error rate decreased, but the error rate of certain confusable phones was higher. In order to solve this problem, we propose the use MPE (Minimum Phone Error Discriminative Training) to solve this problem.

在语音辨识技术的实际应用上,语者调适技术常被用做调整语者无关之声学模型,使其对於特定语者之辨识率有所提升,常见的语者调适技术有最大化相似度线性回归(Maximum Likelihood Linear Regression),其精神在於透过对语音辨识模型相近的mixture做群聚,再对各个群聚做调整,以期能达到利用少量语料,提升辨识率的目的,但其缺点为,在发音上相近的模型,其mixture原本就极为近似,若再分类为同一群聚做调整,容易因为使用者的发音习惯,而使模型偏向ㄓ或ㄗ,因此虽然整体的辨识率获得提升,但却造成混淆音的错误率上升。

Nevertheless,due to the respect of the traditions of the West for the lin guistic norms and logical determinativeness,the word"being"has been raised to the height of the th ing -in -itself of the world and real substance and thereupon,it has got the dual meanings of"be"as a link verb and"exist"as a transitive verb,thus embodying the unity of the logos spirit and the nous spirit in the w.

西方哲学自古希腊以来的一个核心概念Being的原始含义固然是一个逻辑系词&是&,但由西方传统对语言规范及其逻辑确定性的尊重使这个词上升到了世界本体和真正实体的崇高地位,从而使它带上了系词&是&和动词&存在&的双重含义,体现了西方文化中逻各斯精神和努斯精神的统一,这是中国古代以农业为本的文化传统所难以理解的文化现象和语言现象。

The Solidification temperature range was defined as 110-200℃ by DSC analysis. More accelerant used can increase the casing samples dynamic performance, but more than enough accelerant can induce a severe solidified reaction that result in a smaller polymeric meshwork and reducing the sample's performance. Normally the Accelerant dosage can be 2 portions; The Epoxy resin CFRP has a obvious better performances than the Vinyl-ester Resin CFRP, i.e. had a Bend Strength of 1516MPa, LSS of 85MPa, also Tg raised to 195~C~ When used the end-carboxyl polyether to reinforce the epoxy resin, the casing sample's SS, BS and Crack Elongation all increased geminately. The CFRP performance also increased a little, that is because the performance of the CFRP mainly contributed by the CF. The reinforced resin improved the interface between the CF and resin that contribute to the little increasing.

通过DSC分析确定了该环氧树脂的固化温度范围为110~200℃,促进剂增加会提高浇注体力学性能,但过多的促进剂会使固化反应剧烈,聚合网络减小,使浇注体性能下降,一般用量为2份左右;以环氧树脂为基体的复合材料性能明显比以乙烯基酯树脂的性能提高,弯曲强度达到1516MPa,层间剪切强度达到85MPa,同时Tg也上升到195℃;用端羧基聚醚增韧环氧树脂后,其浇注体的拉伸强度、弯曲强度及断裂伸长都成倍增加,复合材料的性能也有所提高,但提高幅度不大,因为复合材料的力学性能主要由碳纤维承担,树脂增韧后改善了复合材料的界面性能。

But as the special geological condition,irrigation causes a series of problems of agroecological geology,such as landslide,salination and so on.

长时期的引水灌溉使土壤理化性质发生改变,并由此引发了地裂缝、滑坡等地质灾害,同时地下水水位的上升,使地表土壤盐渍严重。

We have incorporated a hydraulically actuated lashing device that either lashes the inner of the lifter to the outer body or detaches the body from the internals of the lifter,thereby not translating the motion from the cam onto the pushrod,"said Nandu Srinivasan,Manager of Advanced Engineering for Engine Air Management Operations at Eaton Corp."

我们已经合并了这种液压驱动装置,即可以使挺柱内部零件和外体紧固,也可以使外体和内部零件分开,当松开时就不会将运动从凸轮传递给出推杆,Nandu Srinivasan,伊顿公司的发动机进气管理工程部门的经理说:&当推杆上受到液压时,它会分开外体,由于没有互相锁定,推杆基本上是在凸轮上,上升下降,就像伸缩望远镜杆一样。&

The understandings of overstepping "practical philosophy" and practical ontology pay attention toMarx"s change on the starting point of philosophy, it closely understands Marx"s revolutionary change on philosophy, but that Marx oversteps Feuerbach is not to make his philosophy overstep the opposite between materialism and idealism, but to make his philosophy proceed on the way of materialism, and develop to be practical materialism.

超越的&实践哲学&理解和&实践本体论&理解注意到了马克思在哲学出发点上的转换,这接近了理解马克思在哲学上的革命变革,但马克思超越费尔巴哈不是使他的哲学超越唯物唯心的对立,而是使他的哲学在唯物主义道路上前进,上升为实践的唯物主义。

On the basis of experiment analyses we would got that, When arc met with chute, it was blocked and had a stagnation, this made hot gas flow incrase near the chute; After arc went into the chute, mental vapor from arc root would lower the dielectric strength near the chute, meanwhile, High value of arc voltage and the corase face of the chute made electric strength increase. These factors might give rise to local restriking near the chute, and made arc voltage drop suddenly.

总结实验结果并加以分析,本文提出了这样的观点:电弧进入栅片时,在入口处受阻后的停滞,会使该区域的热气流增加;进入栅片后,弧根蒸发的金属蒸汽、电弧热气流会降低栅片入口区域的介质强度;电弧被栅片分割后,电压急剧上升,再加上栅片表面的不均匀会使局部区域的电场强度显著增加,这些因素的综合作用会导致电弧在栅片入口附近发生局部重击穿,引起电弧电压电压跌落。

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Objective To investigate the effects of interleukin-1 β converting enzyme gene on the biologic characteristics of ovarian cancer cells.

目的 探讨白细胞介素-1 β转换酶的表达,对卵巢癌细胞生物学特性的影响。

Campylobacter: This illness is the most commonly identified cause of diarrheal illness in the world.

弯曲:这种病是最常见的原因查明腹泻病,在世界上。

Gangs fill the daily lives of many of our poorest and most vulnerable citizens with a terror that the court does not give sufficient consideration, often relegating them to the status of prisoners in their own homes.

法院没有充分的考虑到黑社会的猖獗所带来的恐怖,这使得我们最穷、最可怜的市民每天生活在他们的阴影当中,成为在家的囚犯。