作用

This paper has studied the physiological and biochemical changes during the period of forming strong buds of tree peony, and expect to provide academic basis for extending its view value and economic benefit . The main results are as the following:1 Under the field condition, Characteristics of photosynthesis of tree peony are very regular. From before blooming to the prophase of abducting buds that after blooming ,that is April,May and June,the net photosynthetic rate of tree peony is higher than the other period .It indicates that this period is very important for accumulating photosynthetic products of tree peony . So, if we want to get quality flower of tree peony ,it is very important to strengthen the management of tree peony cultivation and to ensure provide the fertilizer and water.2 From the middle ten days of June, with the time elapsing and with the environment conditions worsening, the characteristics of photosynthesis of tree peony decline deeply. But it is different among different tree peony breeds. For example , cv. Wu Long Peng Sheng can also has higher net photosynthetic rate, it indicates that cv. Wu Long Peng Sheng is super than the other two tree peony breeds when adapting the environment conditions and cv. Wu Long Peng Sheng has wide prospect to extend .3 The main factors of effecting the characteristics of photosynthesis are stomatal factor and non-stomatal factor ,that is the ability of photosynthesis of leaf cells. Under the environment of high light intensity in midsummer, if overshadow tree peony properly, then it can slow the declining of chlorophyll content, and increase the net photosynthetic rate and benefit for the accumulating of photosynthetic products.4 The content of soluble sugar in the root of tree peony is the highest among different organs during the period of forming strong buds . According to analyse ,we believe that the soluble sugar will compose starch then, and provide the solid base of material for the growth and development next year. It provide us strong academic basis of adopting the method of cultivating root and protecting root under thefield environment conditions .In other words ,it will help to increase the health level of the whole plant of tree peony and will be beneficial to forming quality tree peony flower if we strengthen the management of root. 5 To tree peony, the endogenesis hormone is important for its growth and development .In the prophase ,that is about the blooming of tree peony and the mid-summer ,IAA and ZR contents are higher and GA content is lower and its changes are very little, and the content of ABA is decreasing . This indicates that IAA and ZR act the important promote function for growth and development of tree peony in this period, and the function of GA is not important. Bur in the period of anniversary senescence of tree peony , the content of IAA and ZR begin to decrease ,while the ABA content has a certain rebound .T

本研究对几个牡丹品种壮芽形成过程中的某些生理生化变化做了研究，以期了解牡丹生长发育过程中生理生化的变化规律，探讨大田栽培条件下提高牡丹花质量的栽培措施和管理技术，为提高牡丹的观赏价值和经济效益提供理论依据，结果如下：1 大田栽培条件下，牡丹光合特性在生长发育过程中表现出极强的规律性，牡丹各品种的光合速率从牡丹开花前，到牡丹花谢后的花芽诱导期前期（6月10日之前），也就是在4、5、6月份，各牡丹品种的净光合速率相对与其他时间都维持在比较高的水平，这说明，在这段时间，是牡丹光合产物积累的重要时期，因此，要保证得到高质量的牡丹花，在这段时间加强对牡丹的栽培管理，保证这个时期的肥水供应十分重要。2 从6月中旬后，随时间的推移，环境条件的恶化，牡丹的光合性能剧烈下降，但是不同牡丹品种间仍有差异，比如，乌龙捧盛仍可维持较高的光合水平，这说明了乌龙捧盛这个牡丹品种对于环境的适应性较之其他牡丹品种高，有着广泛的推广前景。3 影响牡丹光合性能的主要因子是气孔因素和非气孔因素即叶肉细胞的光合能力，在盛夏高温高光强的环境条件下，对牡丹进行适当遮荫，能缓解牡丹叶绿素水平的下降，适当提高Pn，有利于光合产物的积累。4 可溶性糖在牡丹各品种的壮芽形成过程中，根中可溶性糖的含量在牡丹各部位中始终维持最高水平，分析认为这些可溶性糖在根系中进一步合成淀粉等储藏性物质，为来年牡丹的生长提供雄厚的物质基础，这为我们在大田栽培条件下对牡丹采取养根护根的栽培措施提供了有力的理论依据，即在大田栽培条件下，加强对牡丹根系的管理，有助于提高牡丹整株的健壮程度，有益于形成高质量的牡丹花。5内源激素对牡丹的生长发育调节作用是十分明显的，在前期，即开花前后和盛夏，IAA和ZR含量维持在比较高的水平，GA含量低且变化不明显，ABA含量逐渐降低，说明了IAA和ZR对牡丹在这段时间内的生长发育起到重要的促进作用，GA的作用不是很明显，ABA可能在高温高光强下有明显的升高，也说明了ABA的确有一些促进作用，但是到了牡丹周年衰老期，IAA和ZR的含量开始下降，ABA含量却有了一定程度的反弹，说明了IAA和ZR的作用开始降低，ABA起到了促进衰老的作用

DCs acquired by our reformed methods express both CD83 and CD 14 molecules highly, and have a higher density than other domestic reports. The higher TNF in DCs culture medium of HC patient suggests DCs in patient still have antigen presenting ability and by optimization the culture medium would improve its presenting ability and have a potential value in design and application individual vaccine. Although antigens pulsed DCs have a decrescent antigen presenting ability but BCG HSP70 could induce its mature and improve its presenting ability. Suggests BCG HSP70 would be a useful mature inducer. Lymphocytes primed by DCs based HC vaccine have the specific cytotoxicity against HCC lines. The CTL after freezing and anabiotic could prophylaxis and therapy HC xenograft on nude mouse. The results also suggests that CD4〓 lymphocytes play a important role in HC with a good differentiation and would be useful in treatment this kind of HC. After being activated by Peptide LLNQHACAV of hAFP and apoptotic HCCs pulsed DCs respectively, the culture medium of activated lymphocytes both contains a high level Th1 cytokines IL-12 and TNF. Primed lymphocytes appeared a characteristic of NK cells. DCs not only inhibited the growth of human HCC and other cancer cells in vitro but also prevented the growth of HC xenograft on nude mouse in vivo. There are at least three kinds of mechanism playing important role in DC based vaccine ,there are inhibition of DCs, HC specific CTL and cytokines pathway.

诱导出的DC共同表达CD83和CD14分子，CD83分子表达明显高于国内报道；肝癌患者DC培养上清中TNF水平高于健康人，提示肝癌患者DC仍具一定的抗原呈递能力，适当调控可使其行使APC功能，以期在肝癌个体化疫苗中发挥作用；DC负载肝癌可溶性抗原后，抗原呈递能力降低，BCG HSP70可促进DC成熟，增加其抗原呈递能力，预示BCG HSP70有可能成为促进DC活化和成熟的另一重要分子；肝癌DC疫苗在体外诱导肝癌特异性淋巴细胞，活化的淋巴细胞在体外对肝癌细胞的杀伤以特异性CTL为主，同时分泌较高水平Th1型细胞因子IL-12和TNF，并抑制4种肝癌细胞生长；冷冻复苏后的肝癌特异性淋巴细胞可以预防和抑制人肝癌裸鼠皮下移植瘤，提示DC负载肝癌可溶性抗原后诱发的MHC-Ⅱ类限制性CD4〓T细胞有可能在分化程度高的肝癌治疗中发挥作用；用DC和HLA-A2〓DC分别负载凋亡肝癌细胞和hAFP218-226位LLNQHACAV HLA-A2限制性九肽，在体外诱导肝癌特异性淋巴细胞，活化后的CTL细胞分泌较高水平的Th1型细胞因子IL-12和TNF，并具较强杀伤活性，此CTL同时具备NK细胞特征；DC对肿瘤细胞的抑制作用可能是通过吞噬实现的，Fas-L在DC抑制中也起一定作用；DC对人肝癌裸鼠皮下移植瘤的抑制率为97％；在肝癌DC疫苗的作用中，至少联合3种以上机制，即通过DC的直接作用、肝癌特异性CTL和细胞因子途径直接或间接地杀伤和抑制肝癌细胞。

It has good control effect, and its action mode has stomach poison, contact killing, antifeedant, fumigation and anesthetization.

发明人多年来对雷公藤根、茎、叶等植物组织用酸水提取法、乙醇提取法、氯仿热提甲醇沉淀法提取的浸提物进行了杀虫谱和杀虫效果的研究，发现雷公藤浸提物对众多农业害虫和园林树木害虫具有较好的防治效果，其对害虫的作用方式有胃毒作用、触杀作用、拒食作用、熏蒸作用、麻醉作用。

The biometallogenesis system of Jinya gold deposits consists of the following procedure: pre-concentration of gold and metallogenic matter in living organisms in Luodian-Danchi rift depositional basin; solution, absorption and concentration of metallogenic matter in organic matter and organic thermal fluid generated from organisms during lithogenesis; migration of gold and metallogenic matter in organic fluid from basin to Lingyun underwater carbonate platform and concentration at its boundary convex (palaeo-blind-mountain) during basin compaction ; metallization due to depth thermal fluid making organic fluid thermal degradation and forming new fluid which riches in gold and sulfur, and the fluid migrating upward and depositing in upside ore-controlling structures because of absorptions by organic carbon and atc.

通过研究金牙金矿作用的生物成矿系统内容为：在早、中三叠世罗甸—丹池裂谷盆地接受沉积时，生物对金等成矿物质就存在预富集作用；在成岩过程中，生物转化为有机质及有机热流体，对生物及沉积物中的金等成矿物质存在溶解、萃取、富集作用；在盆地压实成岩作用中，盆地中有机热流体向凌云水下碳酸盐台地运移，并在台地边缘外凸部位集中，此过程流体携带大量成矿物质，对金等成矿物质存在迁移集中作用；深部热流上侵使有机流体发生降解和释放金的热作用、形成高含金的有机热液，含金热液上移在构造通道中沉积并被有机碳再次吸附，最终形成金矿床，对金存在成矿作用。

Base on core observation and grain size analysis, and under associated consideration of logging trace characteristics, Chang8 reservoir in study area is classified into three sedimentatal microfacies, subsea river, mouth bar and river flank.3.The mian diagenesis in study area are: mechanical compaction, cementation, metasomasis and denudation in late diagenetic phase.4. In allocation of reservoir macroscopic heterogeneity, more heterogeneticer reservoir, class 1 and class 2, mainly locate in the center of subsea river or crook and divaricate of the river; class 3 and class 4 mainly locate in river flank, and the physical property of these locality are better.5. Diagenesis of reservoir have influence on the pore structure which influences the reservoir microscopic heterogeneity. The better the pore structure is, the slighter the reservoir microscopic heterogeneity is; on the contrary, the reservoir microscopic heterogeneity is serious.

本次研究所取得的主要成果及熟悉有：1、将合水地区长8储层细分为6个小层：长8_1~1、长8_1~2、长8_1~3、长8_2~1、长8_2~2和长8_2~3.2、依据岩心观察和粒度分析，并结合测井曲线特征，研究区长8储层分为水下分流河道、河口坝和河道侧翼四种沉积微相。3、研究区主要经历的成岩作用有：机械压实和压溶作用、胶结作用、交代作用、晚成岩期溶解作用。4、从宏观非均质性平面展布特征来看研究区宏观非均质较强的1类和2类区主要分布于水下分流河道中间或河道拐弯和分又处。3类和4类往则主要分布于水下分流河道侧翼，这些地方储层均质性相对较好。5、储层成岩作用影响储层的孔隙结构，储层的孔隙结构又对储层的微观非均质性有不同程度的影响，孔隙结构越好，则储层的均质性越好，储层的孔隙结构差，则非均质性强。

During the Cenozoic, the evolution of the sag might be divided into three stages: during the Eocene, because of regional extension effect of the NW-SE-striking, it was a ramp depression controlled by the Cangdong fault; during the Oligocene, it might have subjected to the combined effects of the NW-SE-striking regional extension and the dextral slipping of the NNE-striking deep fracture zone; during the Neocene and the Quaternary, though the regional extension had mainly stopped, the dextral slipping continued. Inside the slip zone, the local, SN-striking extension related to the dextral slipping became more and more apparent.

新生代演化分为3个时期：NW-SE向区域伸展作用，凹陷是一个由沧东断层控制的断坡凹陷；渐新世，凹陷受NW-SE区域伸展和NNE向深断裂带右旋走滑的共同作用；晚第三纪到第四纪，区域伸展作用基本停止，走滑作用仍在继续，由走滑作用导致的SN向局部伸展作用显得更加突出。

The results indicated that the fragments (HF3～HF8) with higher MW (≥3000) but not those (HF1, HF2) with lower MW (＜3000) had effects on CFU-MK growth. Moreover, HF3～HF8 could act synergically with TPO(10ng/ml) in promoting CFU-MK growth, but HF1, HF2couldnot. In addition, there were no differences in the effects ofHF3～HF8 on CFU-MK growth, suggesting that the synergy of heparin with TPO was associated with its MW, but not its sulfate content or activity of anticoagulation.

结果表明分子量较小的HF1和HF2(＜3000)没有促进CFU-MK生长作用，而分子两较大的HF3～HF8具有促进作用，并且前2者没有协同TPO(10ng/ml)的作用，后6者都有协同作用，后6者之间的作用比较没有差异，提示肝素协同TPO的作用与其分子量有关，而与硫酸基团含量和抗凝活性无关。

Kangdai Ⅰ has protective function to the damaged neurons and astrocytes: Main results:(1) It has direct protective function to the damaged neurons. It can increase the activity and survival rate, decrease the mortality and the transudation rate of LDH in cultured medium and the strong positive cell count of NOS expression of injured neurons.(2) It has also directly protective function to the damaged astrocytes. It can increase the activity and survival rate and protein content in conditioned medium.(3) It can strengthen the ability of BDNF, GDNF, bFGF, HSP and IL-6expression in damaged astrocytes.(4) It can also strengthen obviously the expressions of NSE, bFGF-receptor and bc1-2, lower the expression of bax and caspase-3.(5) It can indirectly protect and restore the damaged neurons by astrocytes. Because the effect of ACMK (ACM interfered by Kangdai Ⅰ) is stronger than ACM+K (ACM associated with Kangdai Ⅰ).

抗呆Ⅰ号对受损的神经元和星形胶质细胞均具有保护作用：主要表现为：(1)对受损神经元具有直接的保护作用，可提高受损神经元的活性和存活率，降低细胞培养液LDH的漏出率、细胞死亡率和NOS染色强阳性细胞的表达量；(2)对受损的星形胶质细胞也有直接的保护作用，可提高其活性、存活率以及培养液蛋白质的含量；(3)能增强受损星形胶质细胞分泌BDNF、GDNF、bFGF、HSP和IL-6的能力；(4)可明显增强受损神经元对NSE、bFGF的受体和bc1-2的表达，降低受损神经元对bax和caspase-3的表达；(5)抗呆Ⅰ号可通过星形胶质细胞间接地保护和修复受损的神经元，因为在多数实验组中经抗呆Ⅰ号作用的ACM的作用远大于ACM与抗呆Ⅰ号联合应用的作用，统计学上具有显著性差异。

Results The diagenetic grade of Permian rift basin was quite high, and the mechanical compaction resulted in the great loss of the original pore. The eodiagenesis and telodiagenesis were important to the reservoir, and fractures were the dominant hydrocarbon migrating pathway and accumulating space; In Triassic-Paleogene Formation, mechanical compaction was as important as pressolution, and the most original pore was preserved. The exodiagenesis stage of late hercynian movement, indosinian movement and Yanshan movement played the vital role in the diagenetic evolution and hydrocarbon migration and accumulation of the basin. The argillaceous dolomite and algal dolomite discaved in Permian, which were formed probably by hybrid process in high salinity lake which had the fresh water interfused in.

结果 二叠纪裂谷盆地的成岩强度大，以机械压实作用为主，原生孔隙丧失多且早，晚期成岩作用较重要，裂缝是油气运聚的通道和空间，可出现次生孔隙发育带；三叠纪－古近纪拗陷盆地的成岩作用表现为机械压实和化学压实作用并重，原生孔隙多被保留；晚海西、印支、燕山运动等表生成岩阶段对该区的成岩演化和油气运聚起到重要作用；二叠系中特征的泥云岩和藻云岩可能是在有淡水注入的较高盐度湖泊中经混合作用而形成的。

This paper deals with and summarizes the research and importance of ductile shear zones and presents the future direction and aim for the research of the ductile shear zones around the world. Four aspects of studies of the ductile shear zones have been proposed in this paper as follows:(1) The stress environment including the mineral assemblages, deformation, stress-shearing parameters;(2) The major element sequence and activation under condition of stress;(3) The variations of trace elements and REE, their transportation distributions under strong natural deformation as well as variations of mineral crystal parameters, which can also control the element changes during the ductile deformation;(4) The relationship between element migrations, activation and stress, which will present the new evidences for the studies of dynamic diagenesis and mineralization as well as the studies of evolution of ductile shear zones developed in middle and low levels.(5) The analysis of elements and isotopes in mylonites on the micro-scale are crucial for the understanding of component migrations during the mylonization.

对韧性剪切带及其变形岩石的研究现状和研究意义进行系统的综述，提出了未来韧性剪切带及其糜棱岩的研究方向和目标：①系统研究糜棱岩中主要造岩矿物组合及其变形特征，计算剪切变形岩石的应力－应变参数，搞清韧性剪切带所处的应力应变环境；②系统研究韧性剪切带岩石在天然分强剪切应力作用条件下常量元素迁移机制及活化转移的应力排序问题；③系统研究剪切变形作用过程中岩石化学组成的微量和稀土元素变化，讨论强变形条件下岩石中微量元素活化和迁移规律，深入探讨微量元素迁移的动力控制，包括稀土元素配分变化的应力制约以及应变矿物晶格化学变化行为及其对其寄主的变形岩石元素在应变过程中迁移变化的制约和影响；④从理论上探讨天然强剪切应变条件下岩石中组分活化、转移与应力的因果联系，为深入探讨韧性剪切带动力成岩作用提供理论的科学依据，为探讨中、下地壳中韧性剪切带的形成和演化提供科学依据，同时为韧性剪切变形作用条件下成岩、成矿地球化学作用提供理论和实验依据；⑤现代分析技术如激光同位素原位分析以及激光ICP-MASS分析技术对研究变形域内的岩石的元素和同位素的活化迁移规律，对深刻揭示糜棱岩化过程中的元素活化迁移机制提供更高质量的地球化学证据具有重要的作用。

Objective To investigate the effects of interleukin-1 β converting enzyme gene on the biologic characteristics of ovarian cancer cells.

目的 探讨白细胞介素-1 β转换酶的表达，对卵巢癌细胞生物学特性的影响。

Campylobacter: This illness is the most commonly identified cause of diarrheal illness in the world.

弯曲：这种病是最常见的原因查明腹泻病，在世界上。