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上纤维化

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Simvastatin may suppress interstitial fibrosis by effect CTGF、suppress cell proliferation、redue extracellular matrix accumulation.

辛伐他汀可以抑制CTGF、抑制肾小管上皮细胞的转分化、减轻细胞外基质的积聚,从而减轻间质纤维化,发挥肾保护作用。

DISCUSSION:Extensive interstitial and alveolar fibrosis results in the characteristic HRCT finding of honeycombing or honeycomb lung.

讨论:广泛的肺间质及肺泡纤维化在HRCT上的特征性表现为蜂窝样改变,或称为蜂窝肺。

DISCUSSION:Extensie interstitial and aleolar fibrosis results in the characteristic HRCT finding of honeycombing or honeycomb lung.

讨论:广泛的肺间质及肺泡纤维化在HRCT上的特征性表现为蜂窝样改变,或称为蜂窝肺。

Patients in later series had neither risk factors for osteonecrosis nor osteonecrosis at other extraskeletal sites; instead osteoporosis and significant cardiovascular morbidity/atherosclerosis was found in most of the patients.6,19,21 Other findings suggesting an ischemic etiology in these patients is absent enhancement on MRI of the affected vertebrae,7,15,20 "ischemic bone" noted intraoperatively,14 and vertebral body biopsies demonstrating reactive bone/fibrosis and occasionally osteonecrosis and hyalinized marrow.

以后病例系列中的患者既没有引起骨坏死的因素,在其它地方也没有出现骨坏死,而是骨质疏松症和显著的心血管疾病/动脉粥样硬化发病率[6,19,21],其他的发现表明,在这些患者受影响的椎体上MRI不会出现增强影[7,15,20],术中可看到&缺血性的骨块&[14],椎体活检可看到有活性的骨/纤维化,有时可见骨坏死和玻璃样变[8,11,14,16,17,30,31]。

The potential for enhanced ETV activity is supported by the observation that exogenously added deoxyguanosine reversed the potentiating effect of ribavirin and MPA.

所选抗生素治疗如有效体温一般在治疗3~10天内降至正常,宜持续8~12周,直至胸X线上空洞和炎症消失,或仅有少量稳定的残留纤维化。

Ample evidence that fibrosis regresses with control of hepatitis B, hepatitis C, or other chronic liver diseases[2] attests to the tremendous regenerative power of the liver, and the rapid progress made in the development of targeted antiviral and disease-specific treatments.

在乙肝、丙肝和其它慢性肝病得到控制以后,纤维化是可以逆转,这方面已经得到了足够的证据证明肝脏巨大的再生能力以及在靶定抗病毒和疾病特异性治疗上所获得的快速好转。

Pathologic examination included: tubulointerstitial lesion which was the main pathologic presentation, tubular epithelial cell becoming flat, TEC necrosis and wither, departure between the cytoplasm and basis membrane, drops of protein in cytoplasm, broken basic membrane of TEC, inflammatory cells infiltrating in tubulointerstitium, tubulointerstitium fibrosis, plasm cell infiltration.

MM肾损害主要以小管-间质病变为主,病理表现为肾小管上皮细胞扁平,存在不同程度变性、坏死或萎缩,胞浆与基膜分离,胞浆内可见蛋白滴,甚至小管基膜断裂,间质炎性细胞浸润、纤维化,部分有淀粉样物质沉积,较少见浆细胞浸润。

Results Among 13 variables associated with liver fibrosis selected by univariate analysis, age, gamma glutamyltranspeptidase, hyaluronic acid, and platelet count were indentified by multivariate logistic regression analysis as independent factors of fibrosis.

在模型组,对指标依次行单因素分析和多因素Logistic回归分析,筛选出与研究终点相关的独立预测因子,在此基础上构建诊断肝纤维化的指数模型,最后在独立的验证组中检验模型的诊断效率。

Degradable biomedical membrane is a biological barrier membrane, whose mechanism is to segregate the inflamed or trauma from the tissue and prevent the fibroblast inrushing the traumatic surface. And the controllable degradation time can assure the trauma of insulating until metaplasia. The membrane can effectively avoid the adhesion.

生物可降解医用膜作为生物屏障膜可有效防止术后粘连,其作用机理是将炎症或损伤部位与周围组织隔离开来,阻止周围组织中成纤维细胞对创面的入侵,而其降解时间的可控性能保证有效隔离直到损伤部位再上皮化,从而达到预防粘连形成的目的。

In end stage sarcoidosis we will see fibrosis, which is also predominantly located in the upper lobes and perihilar.

在结节病的最后阶段,我们可以看到主要在上叶和肺门周围的纤维化

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