上纤维化

This study investigated the mechanisms that induce EMT and the significance of extracellular signal-regulated kinase cascade in this course in vitro.

本文旨在研究酸性成纤维细胞因子对上皮-间质转分化的影响，探讨有丝分裂原激动蛋白激酶的ERK信号传导途径在此过程中的作用，为肾小管-间质纤维化的防治提供理论依据。

In the first week of renal obstruction, the immunohistochemical labeling of tubular VEGF was intensified, accompanied by deformation and dilation of adjacent Flk-1-positive PTC lumina, mild renal tubular cell apoptosis and minimal tubulointerstitial fibrosis.

结果： 1。肾脏梗阻第一周，肾小管上皮细胞胞浆里的VEGF染色在局部有增强，Flk-1阳性PTC数量变化不显著，肾小管上皮细胞凋亡和肾间质纤维化很少见。

Aminoglycosides suppress termination at nonsense codons and result in functional improvement in a cystic fibrosis bronchial epithelial cell line, in muscle cells from mdx mice and in fibroblasts from individuals with Hurler syndrome.

氨基糖苷类物质可以通过抑制无意义密码子的终止作用，改善囊性纤维化的支气管上皮细胞、患肌营养不良的肌细胞和Hurler综合征病人的成纤维细胞的功能。

And the overgrowth lesions are characterized by epithelial acanthosis, with long, branched rete peg formation, and the excessive accumulation of radiating collagen fibers in the connective tissue layer.

此种疾病在组织学上的特徵为：上皮细胞层数有增厚的发现，并呈现明显的棘状凸出延伸至结缔组织中，在结缔组织中则有大量胶原蛋白堆积而产生纤维化；然而引发牙龈增生的病理机制至今仍不明确。

Objective To study the effects of Aralia chinesis on the proliferation and viability of fibroblasts and on the production of the hyaluronic acid in the cultured supernatant, and to explore its anti-hepatofibrosis mechanism.

目的 探讨太白楤木对成纤维细胞增殖、活力及对培养上清中透明质酸产生的影响，研究太白楤木抗肝纤维化机制。

Jq Ez6_{0An outbreak of highly pathogenic avian influenza caused by H5N1 virus occurred in Vietnam, Japan and Korea, commencing in December, 2003. By February, 2004, it has been distributed widely in Asia and brought heavy losses. H5N1 are ball-like RNA viruses, birds can shed them via respiratory system, ocular secretions and feces, sometimes transferred to human and cause lethal infection. H5N1 patients have prominent features of reactive hemophagocytic syndrome,bronchiolar inflammation, necrosis of bronchial epithelium and organizing,diffuse alveolar damage with interstitial fibrosis.

2003年12月，H5N1型禽流感病毒在越南、日本和韩国爆发，到2004年2月，该病毒已在亚洲广泛蔓延并带来了巨大损失。H5N1是球型RNA病毒，禽类间可通过呼吸系统、眼分泌物和粪便传播，也可传染人类甚至导致死亡。H5N1感染者的特征是反应性噬血细胞综合征、细支气管炎症、支气管上皮坏死和机化、弥漫性肺泡病变和间质纤维化。

No IOL decentration was found. In group A, there were 6 eyes had PCO, and only 1 eye in group B. PCOCAAS software analysis had statistical significance.

囊袋张力环在一定程度上可以抑制晶状体上皮细胞的纤维化生，降低了后发性白内障的发生率。

All kind of structure changes do not occur at the same time, for example the epithelial desquamation occurring after exposure for 1 week and sub- epithelial fibrosis occurring after exposure for 8 weeks, and it is incomplete that the prevention of inhaled corticosteroids on airway remodeling. So inhaled corticosteroids should be introduced to treat asthma as early as it possible.

5哮喘气道重塑过程中，气道结构的各种改变是不同步的，气道上皮脱落在激发1w后即可发生，而上皮下纤维化在激发sw后出现，且ICS对气道结构改变的防治是不完全的，故临床上应及早使用ICS治疗，并结合其他抗炎剂如白三烯受体拮抗剂以最大程度地防治气道重塑的发生。

The Ganzhiping capsule composed of Jianghuang Chishao Haizao Fuling and compositon E has the efficiency of soothing the liver to regulate the flow of vital energy, strengthen the spleen by oozing wet firmly of invigorating blood circulation etc. It can effectively prevent and cure the fatty liver and acute liver-damage and chronic hepatitis cause to liver fibrination in clinic.

肝脂平胶囊是由姜黄、赤芍、海藻、茯苓和提取物E提取研制而成，具有疏肝理气、活血化瘀、软坚散结、健脾渗湿的功效，可有效的预防和治疗临床上的脂肪肝和急性肝损伤及慢性肝炎引起的肝纤维化等症。

Theurinary IL-6 level positively correlated with density of glomerular matrix membrane, global sclerosis, fiber or fibrocellular crescents and interstitial fibrosis (p. 05). According to the degree of density of glomerular matrix membrane and interstitial fibrosis, urinary Col-IV level had better correlation than urinary TGF-betal and IL-6 levels.In IgAN, Col-IV showed increased expression in diseased renal tissue whereas the site of expression of TGF-betal was mainly localized within the cytoplasm of tubular epithelial cells. Interstial expressionwas also present but glomerular TGF-betal expression was found only in patients with heavy mesangial proliferation. There was a significant correlation between glomerular positivity for Col-IV and severity of histological damage. There was also a significant correlation between positivity for TGF-betal and Col-IV in the tubular epithelial and interstitial lesions. In contrast, there was no ralationship between glomerular positivity for TGF-betal and severity of histological damage.The urinary TGF-betal level paralleled tubular TGF-betal expression.

结果 ①IgAN患者尿TGF-β1、IL-6、Col-Ⅳ水平较健康人明显增高(P＜0.01)，该变化与血中的浓度无关(P＞0.05)；②尿TGF-β1水平与小管间质TGF-β1阳性表达呈正相关(P=0.000)，而与小球TGF-β1阳性表达无关(P＞0.05)，尿Col-Ⅳ水平与小球和小管间质Col-Ⅳ阳性表达均呈良好的相关性(P＜0.01)，还与小管间质TGF-β1阳性表达呈正相关(P＜0.05)：③小球Col-Ⅳ阳性表达与肾组织慢性病变密切相关(P＜0.05)，小管间质Col-Ⅳ和TGF-β1阳性表达均与肾小管间质病变呈良好的相关性(P＜0.01)，而小球TGF-β1阳性表达与肾组织损伤无关(P＞0.05)；④尿TGF-β1、Col-Ⅳ水平与肾小球基质基底膜面密度、小管间质病变呈正相关(P＜0.01)，与小球内细胞数呈负相关(P＜0.05)，该结果与其在组织中的表达一致；尿IL-6水平浙江大学硕士学位论文尿TGF一B一、IL一6和Col一IV在IgA肾病中的应用价值与基质基底膜面密度、球性硬化、纤维或细胞纤维新月体所占肾小球百分数及小管间质病变均有显著的相关性(F.05)；在轻度肾病理损伤时，尿'l'G卜pl、I卜6、Col一IV水平即升高，而尿Col一W在反映细胞外基质积聚和间质纤维化程度上比尿TGF一pl和IL一6有更好的相关性。

Since historical times,England ,where the early inhabitants were Celts, has been conquered three times .

从有历史以来，英国，在此地早期居住的是凯尔特人，已经被征服了三次。

Bluetooth OBEX File Transfer Enables the sending and receiving of files on your phone via Bluetooth.

蓝牙OBEX文件移动允许经过蓝牙传送和接受文件。。。。