万古

Because of the tremendous increase in the incidence of antibiotic-resistant infections in recent years — especially enterococci that are resistant to penicillins, ancomycin, and aminoglycosides — prior AHA guidelines that recommended these antibiotics for prophylaxis are no longer alid.

因为近些年抗生素耐药性感染的发生率大幅增加－特别是肠球菌耐药的青霉素、万古霉素和氨基糖甙类－先前推荐用这些药物进行预防的AHA指南已不适用。

The company is also working on an inhaled version of vancomycin for treating antibiotic-resistant, hospital-acquired pneumonia.

公司正在研制万古霉素的一种吸入剂型用于治疗耐药性医院获得性肺炎。

Objective: To establish a reverse-phase high performance liquid chromatographic assay for the determination of vacomycin levels in rabbits aqueous humor.

目的：应用反相高效液相色谱技术，建立定量检测兔房水万古霉素的方法。

To date, four strains of vancomycin-resistant S aureus have been reported.

迄今为止，已经报道了四种耐万古霉素的金黄色葡萄球菌菌株。

OBJECTIVE In order to control the resistance in Methicillin-resistant Staphylococcus aureus to vancomycin and norvancomycin were studied.

目的：为防止临床耐万古霉素耐甲氧西林金黄色葡萄球菌的产生。

Results The drug concentration of vancomycin was not the only factor that influenced the severity of nephrotoxicity for the elderly patients.

结果 万古霉素的血药浓度不是影响其肾毒性的唯一指標，而APACHE评分有助於预测万古霉素的肾毒性。

Vancomycin was directly coupled onto Tenta Gel S NH〓 or PEGA resin through its C-terminus. HR/MAS NMR studies indicated that conformation of PEGA-bound vancomycin was the same as free vancomycin, and Ac〓-L-Lys-D-Ala-D-Ala interacts with PEGA-bound vancomycin the same way that it interacts with free vancomycin.

本文将万古霉素C端分别连接到Tenta Gel S NH〓和PEGA树脂上，利用高分辨魔角核磁共振技术研究了万古霉素在固相载体上的构象变化以及与Ac〓-L-Lys-D-Ala-D-Ala的相互作用。

This study demonstrated the native-like conformation and interactions between molecules on a proper physically charactering resin, which additionally provides evidence of on-bead screening on the basis of molecular recognition.

结果表明：固载在PEGA树脂上万古霉素在DMSO中与万古霉素自身的构象相同，而且固载在PEGA树脂上万古霉素和Ac〓-L-Lys-D-Ala-D-Ala的相互作用方式与万古霉素自身和配体形成复合物的方式相同。

But there is no specific and selective antibacterial agents to kill MRSA. The last treatment option is vancomycin. However, clinical isolations of vancomycin-resistant S. aureus were reported one after another in the United States, France, Australian and this situation is more and more serious.

治疗MRSA感染的最后一道防线是万古霉素，但在美国、法国、澳大利亚相继发现了抗万古霉素的金黄色葡萄球菌，且这一趋势在日益蔓延，因此寻找一种新的控制MRSA感染的策略变得迫在眉睫。

objective to study the infection and sensitivity to antimicrobial agents of staphylococcus of bacterial prostatitis patients.methods the results of bacteriology and drug susceptibility of 421 patients,who were suffered from prostatitis,were analysed retrospectively.results in the 421 succus prostaticus samples,278 strains pathogenic microorganisms of 15 genera were isolated from the 273 succus prostaticus samples,and the major pathogenic microorganisms was staphylococcus aureus(57.2%) and coagulase negative staphylocous（17.3%.the drug resistance rate of staphylococcus to penicilling,erythromycin and albomycin was 88%-97%,and it was 33%-50% to fluoroquinolones.the drug resistance rate of staphylococcus to amikacin,cefazolin,nemycin,rifampicin and cefoperazone was lower than 30%,and they all appeared susceptible to vancomycin.conclusion staphylococcus is the main germ of bacterial prostatitis and it appears high drug resistance to usual antibacterials.staphylococcus is susceptible to vancomycin,amikacin,cefazolin,neomycin,rifampicin and cefoperazone.

目的 探讨细菌性前列腺炎患者葡萄球菌的感染状况及抗菌药物敏感性。方法回顾分析421例前列腺炎患者标本的细菌学和药物敏感性试验结果。结果 421例前列腺液标本，273例分离出细菌，共分离出15个种别共计278株病原菌，其中金黄色葡萄球菌占57.2%，凝固酶阴性葡萄球菌占17.3%；葡萄球菌对青霉素g、红霉素、白霉素耐药率为88%～97%，对氟喹诺酮类耐药率为33%～50%，对丁胺卡那霉素、头孢唑啉、新霉素、利福平和头孢哌酮耐药率均0%，对万古霉素全部显示敏感。结论葡萄球菌是细菌性前列腺炎的最常见病原菌，对临床常用抗菌药物具有较高的耐药性，葡萄球菌对万古霉素、丁胺卡那霉素、头孢唑啉、新霉素、利福平和头孢哌酮较为敏感。

On closer examination, though, this is not a vote for multilateralism but just the opposite.

仔细审视后我们发现，这并非是对多边主义投出的赞成票，而是恰好相反。

Uncovering their weak spots, so I can defeat them.

揭露出他们的弱点，这样我就可以打败他们了。