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These EM images clearly discovered that:(1) all the tested tumor cells came into being CPE;(2) the CPE can be divided into two kinds: The first one is those viruses propagate in a large amount and lyse tumor cells. The other is that viruses propagate to some degree and induce tumor cells apoptosis.

电镜图像明显地揭示出：(1)上述受试肿瘤细胞均产生了CPE；(2)受试肿瘤细胞出现的CPE分为两类，一种是病毒大量增殖，细胞裂解死亡；另一种是病毒有一定量增殖，并诱导肿瘤细胞凋亡。

This paper divided the mix type virus into the mail-virus and worm virus, and then analyzed thoroughly the essential characteristics and spreading means of these three kinds of different viruses. According to characteristic of these viruses, this thesis put out a project of "Intelligent Macro Code Scanning Technique" to macro-virus, a project of "Base of Command Code Scanning Technique" for mail virus and a project of "File Head Check-Up Method" for worm virus to protect file of PE type.

根据这些病毒的不同特征和传播手段等特点，对宏病毒提出了一种"智能宏代码扫描技术"的方案，对邮件病毒提出了一种"基于命令式的代码扫描技术"的解决方案，对蠕虫病毒的解决则是以保护PE格式文件为重点提出了一种"文件头检测法"的解决方案。

Future efforts will monitor the microevolution and macroevolution of influenza viruses in human, avian and swine obtained in the same and different areas over years for better understandings in the mechanisms that emerging novel human flu viruses might have public health significance.

未来及早建立完善的人/禽/猪流感病毒「整合性」侦测系统与流感病毒基因库，对於我国防范新型流感病毒的入侵与研究不同宿主的流感病毒在生态上的微观与巨观演化趋变必有助益。

Wild waterfowl are the natural reservoir of all influenza A viruses, and these viruses are usually nonpathogenic in these birds.

野生水鸟是所有甲型流感病毒的自然储存宿主，通常这些病毒对它们不具有致病性。

Another common family of viruses is the Papovaviridae family of viruses, which includes the Human Papilloma Virus.

另一种常见的病毒家族是乳多空病毒科病毒，其中包括人乳头瘤病毒。

The methods for determination of the complete genome sequences of potyviruses, carlaviruses and potexviruses were also established. The complete genome sequences of 13 viruses(20 isolates) were determined while 10 of them were the first report in the world.Five of them including Lily symptomless virus (NC_005138), Lily mottle virus(NC_005288),Onion yellow dwarf virus (NC_005029), Lily virus X (NC_ 007192) and Shallot yellow stripe virus(NC_007433) were selected as the standard sequences of those viruses by National centery of Biotechnology Information, USA.

建立了马铃薯Y病毒属、麝香石竹潜隐病毒属和马铃薯X病毒属成员的基因组全序列扩增技术，完成了13种不同植物病毒近20个分离物的基因组全序列测定，其中10个病毒的基因组全序列为国际首次报道，百合无症病毒(NC_005138)、百合斑驳病毒(NC_005288)、洋葱黄矮病毒(NC_005029)、百合X病毒(NC_ 007192)和葱黄条病毒(NC_007433)等5条序列被美国国家生物技术信息中心列为相关病毒标准序列的有。

For most viruses,there is aneed for antimicrobials that target unique viral molecular properties.Acycloviris one such drug.It is activated into ahuman herpesvirusDNA polymerase inhibitor exclusively by HHV kinases and,thus,does not suppress other viruses.Here,we show that ACV suppresses HIV-1in HHV-coinfected human tissues,but not in HHV-free tissue or cell cultures.However,addition of HHV-6-infected cells renders these cultures sensitive to anti-HIV ACV activity.We hypothesized that such HIV suppression requires ACV phosphorylation by HHV kinases.Indeed,an ACV monophosphorylated prodrug bypasses the HHV requirement for HIV suppression.Furthermore,phosphorylated ACV directly inhibits HIV-1reverse transcriptase,terminating DNA chain elongation,and can trap RT at the termination site.These data suggest that ACV anti-HIV-1activity may contribute to the response of HIV/HHV-coinfected patients to ACV treatment and could guide strategies for the development of new HIV-1RT inhibitors.

对大多数病毒而言，都需要有针对其分子特性的靶向杀毒剂阿昔洛韦就是这样一种靶向药物在人疱疹病毒酶的特定作用下，阿昔洛韦被激活成为人疱疹病毒DNA聚合酶抑制剂，因此不能再抑制其它的病毒我们的研究发现阿昔洛韦在共感染人疱疹病毒的组织中可以抑制HIV-1，但在无人疱疹病毒感染的组织或细胞中无此作用然而，加入人疱疹病毒-6感染的细胞却使得其对抗HIV的阿昔洛韦变得敏感我们推测这种抑制作用依赖于人疱疹病毒酶导致的阿昔洛韦磷酸化实际上，单磷酸化的阿昔洛韦前体药物无需人疱疹病毒的参与即可抑制HIV此外，磷酸化的阿昔洛韦能直接抑制HIV-1逆转录酶，将其阻止在终止位点，从而终止DNA链的延长这些结果提示阿昔洛韦的抗HIV-1活性决定了艾滋病病毒/人疱疹病毒共感染的患者对阿昔洛韦的治疗反应，也有助于开发新的HIV-1逆转录酶抑制剂

With a persisting development in tumor targeting viruses as a special anti-tumor agent and therapeutic gene vector for the recent years, a number of highly effective, targeting virus vectors have been exploited, which still did not satisfy the requirement for cancer targeting therapy in clinic. However, it has remained unsolved in how to effectively and veraciously deliver these targeting viruses to the tumor tissues.

肿瘤靶向性病毒作为一种特殊的肿瘤治疗药物和基因治疗载体近年来已得到长足发展，许多高效、靶向性病毒载体已被相继研究开发，但仍不能满足临床上肿瘤靶向治疗的需要，如何将这些靶向病毒准确而高效地运输到肿瘤病变部位仍然未得到充分解决。

Oregon State University virologist Dr. Calvin the great danger of these viruses is even more convinced, as "Human health, self-defense mechanism, is not foreseen to those in human society have been lost for thousands of years the virus will re-emerge, so for these viruses and bacteria resistance is very weak, in this case, once the infection occurs This is very likely to lead to large-scale epidemic."

俄勒冈州立大学的病毒学专家加尔文博士对这些病毒的极大危险性更是深信不疑，因为"人类健康的自我防御机制，不会预见到那些在人类社会中已经消失了几千年的病毒会重新出现，因此针对这些病毒和细菌的抵抗能力就很脆弱，在这种情况下，一旦传染发生，就非常可能导致大规模疾病流行"。

We observed the cytopathic effect in rabbit kidney cells culture to isolate viruses,then typed viruses by monoclonal antibody and flurescence antinody technique. In the 1,016 .scraping specimens from cervicitis, vulvitis, vaginit;s and cervlcal cancer, we found72 cases of HSV infection the positive rate was 7. 08% The highest positive rate was 8.7% that was in cervical cancer.

本文应用细胞培养观察细胞病变的方法来分离病毒，再用单克隆抗体及荧光抗体对病毒进行分型，在西宁地区1016例妇科疾病所取标本中（包括宫颈炎，外阴炎，阴道炎及宫颈癌等），共发现单纯疱疹病毒阳性标本72例，阳性率为7.08％，而宫颈癌中阳性率最高为8.7％。

He and Nina moved to California and lived at 2005 Ivar Street, Apt.

他和Nina搬到加州，并在2005年伊瓦尔街，公寓生活。

Droperidol （ potently inhibits transfected HERGchannels and this is the probable mechanism for QT prolongation.

氟哌利多有效地抑制了转染的 HERG 钾通道，可能是 QT 间期延长的机制。