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Correlation of histotypes of phyllode tumor with local recurrence and tumor death was statistically significant at a level of P<0. 001; correlation of infiltrative growth of the tumor with local recurrence was statistically significant at a level of P<0. 001. Tumor necrosis and mitotic activity were independent prognostic factors.

叶状肿瘤的病理组织学等级与肿瘤的局部复发和因瘤死亡有统计学线性关系(P<0.01);肿瘤的浸润性生长方式与肿瘤的复发有线性关系(P<0.01);肿瘤性坏死和核分裂数值是独立的预后因素;术式等11个临床病理因素为单风险预后因素。

Methods The expressions of MAGE-3 in tumor tissue, para-tumor tissue of (5±1)cm from border of tumor tissue, tissue of resection border and polypus were detected by RT-PCR. Results MAGE-3 expression was positive in 14 of 33 (42.42%) samples of rectal cancer, 6 of 33 (18.18%) of para-tumor tissue, and 5 of 33 (15.15%) of resection border tissue respectively.

采用RT-PCR法,对33例直肠癌患者的癌组织及其相应距肿瘤边缘(5±1)cm的癌旁组织和手术切缘以及3例直肠息肉标本的MAGE-3的表达情况进行检测,并对RT-PCR扩增产物中的目的基因片段进行DNA测序验证。

A map was achieved in detail for the optimal placement of ablation electrode. According to assumption of complete destruction of tumor and its 0.5 cm margin by 5.0 cm ablation device with this method, calculating results were obtained as follows: a tumor of 4.1 ~ 4.3 cm in diameter required 4 ablation at least by the regular tetrahedron way, a tumor of 4.4 ~ 5.6 cm in diameter required 5~8 ablation at least by the regular prism way, a tumor of 5.7 ~ 6.0 cm required 12 ablation at least by the three layers overlapping way.

根据RFA治疗原则消融范围须超越肿瘤周边 0 。5cm以上;按照覆盖类球体肿瘤的计算结果,采用伞径 5 。0cm的射频针,治疗 4.1~ 4.3cm的肿瘤须用正四面体法至少布针 4个点,治疗 4.4~5 。6cm的肿瘤用正棱柱法至少布针 5~ 8个点,治疗 5 。7~ 6 。0cm的肿瘤用三层重叠法至少布针 12个点,方能达到较彻底覆盖灭活肿瘤的效果。

In this report, immunohistochemistry and in situ hybridization techniques were perfected to examine the expression of bFGF, fibroblast growth factor receptor-I and bFGFmRNA of cultured HEP-2 laryngo-tumor cell and 803 gastro-tumor cell and of the solid tumor tissue formed by implanting the cultured cells into subcutis of nude mice, intending to elucidate the correlation between the expression level and the tumor formation.

本研究建立了免疫组化和原位杂交的检测方法,通过对体外培养的HEP-2喉癌细胞和803胃癌细胞和这两株细胞在裸鼠皮下形成的实体瘤组织中bFGF,纤维细胞生长因子受体-1(fibroblast growth factor receptor-1,FGFR-1)和bFGFmRNA的检测试图揭示三者在体外和体内表达以及与肿瘤形成的关系,从而为这方面的研究提供更多的材料。

Objective:to study the epidemiologic characteristic of mortality of malignant tumors in zhongshan city.method:selecting the investigated datum of mortality of malignant tumor in zhongshan city as sample uses sas statistics software to analyse and forecast the mortality by time series.results:morlality of male malignant tumor and both male and female malignant tumour showed the risen trend from 1970 to 1989.the trend will be kept in future.both will be separately risen to 121.05/105 and 83.92/105 in 2 000.mortality of female malignant tumour will be kept in about 43.59/105 in 2000.couclusion:mortality of both male and female malignant tumor takes on the trend of diffirent change.the male showed risen trend;the female showed the fluctuation of non-trend random.rising mortality of malignant tumor greatly threaden the crowd health.

目的:研究中山市恶性肿瘤死亡率的流行学特点,为制定防治计划提供依据。方法:以中山市恶性肿瘤死亡率调查资料为样本,应用sas统计分析软件对恶性肿瘤死亡率进行时间序列分析与预测。结果:1970~1989年男性恶性肿瘤死亡率和男女合计恶性肿瘤死亡率均呈现上升趋势且有继续保持的趋势。到2000年将分别上升为121.05/10万和83.92/10万左右;女性恶性肿瘤死亡率呈现无趋势的随机波动且将继续保持下去,到2000年保持在43.59/10万左右。结论:中山市男女恶性肿瘤死亡率呈不同变化趋势,男性恶性肿瘤死亡率呈现上升的趋势,女性恶性肿瘤死亡率呈现无趋势的随机波动。恶性肿瘤死亡率的上升对人群的健康构成重大威胁。

Results The tumors were divided into three types according to the CT findings. Type I: regular, homogeneous density and well-defined,there were 30 patients, included benign mixed tumor(n=29) and adenolymphomas(n=1); Type II:irregular, heterogeneous dentsity, poordefined, there were 15 patients, included benign mixed tumor(n=7), malignant mixed tumor (n=2),adenolymphomas(n=3), hemagioma(n=2),mucoepidermoid carcinoma(n=1). Type III: irregular and could not definded, there were 7 patients, included malignant mixed tumor(n=2), mucoepidermoid carcinoma(n=2), adenoid cystic carcinoma(n=1), malignant lymphoma(n=1), acinic cell carcinoma(n=1). Conclusion CT have important values in location and qualitative analyses of parotid gland.

结果 肿瘤按CT表现分三类:52例患者中,I类30例,形态规则呈类圆形,密度均匀,边缘清楚,除1例腺淋巴瘤外,29例均为良性混合瘤;II类15例,形态不规则,呈分叶状,密度欠均,边界较清或模糊,其中7例良性混合瘤,2例恶性混合瘤,3例腺淋巴瘤,2例血管瘤,1例黏液表皮样癌;III类7例,形态不规则,边缘无法确定,其中恶性混合瘤2例,黏液表皮样癌2例,囊腺癌1例,恶性淋巴瘤1例,腺泡细胞癌1例。

Results among 34 cases of orbital tumor,29 cases were with benign tumor, 5 cases of malignant tumor, 8 cases of hemangioma,5 cases of dermoid,5 cases of inflammatory pseudotumor,3 cases of liparomphalus,3 cases of haematoma,3 cases of mixed tumor of lacrimal gland,2 cases of optic nerve glioma, 2 cases of cancerometastasis,2 cases of adenocarcinoma,1 cases of malignant lymphoma.

结果 34例眼眶肿块患者中,良性肿块29例,恶性肿瘤5例;其中血管瘤8例,皮样囊肿5例,炎性假瘤5例,脂肪瘤3例,泪腺混合瘤3例,血肿3例,视神经胶质瘤2例,腺癌2例,转移性癌2例,恶性淋巴瘤1例。

The result indicate: Erysimum cheiranthoides can obviously inhibit tumor of S180 and H22, enhance the life quality of mice bearing tumor . The mechanism may be: improve the function of immune system , inhibit the growth of tumor cells and accelerate tumor cell necrosis .

通过以上实验研究表明:桂竹糖芥总甙对S_(180)和H_(22)荷瘤小鼠有明显抑瘤作用,提高生命质量,其可能机制是通过改善小鼠免疫功能,抑制肿瘤细胞增殖以及使肿瘤组织大片坏死而实现的。

It will provide the rational for exploring the ideal treatment for liver cancer by detecting the expression of c-Met,hTERT and MAGE-1,which has high expression in liver cancer,in cancer tissues and tissues surrounding tumor by immunohistochemistry,analyzing the different expression of gene in tumor tissue and tissues with different distance from tumor,and then initially debate the molecular boundary in liver tumor exairesis.

通过免疫组织化学方法检测原发性肝细胞癌组织中高表达基因c-Met、hTERT、MAGE-1的表达以及它们在肝癌癌周组织中的表达,分析基因在肝癌组织和癌周不同距离组织的差异表达,初步探讨肝癌的分子切缘,为探索新的治疗肝癌途径奠定坚实的理论基础。

Results The value of NAA and Cho/Cr was decreased obviously.The NAA value,between benign and malignant tumor and between intracerebral and extracerebral tumor,had significant effectiveness.But the Cho and Cr value and the peak ratio of metabolites had no significant effectiveness between benign and malignant tumor and between intracerebral and extracerebral tumor.

结果:几乎所有颅脑肿瘤的NAA峰均下降,Cho/Cr下降;良恶性肿瘤之间、脑内外肿瘤之间的NAA峰值的比较差异有显著性,但其Cho、Cr峰值的比较及各代谢产物的峰值比值的比较差异无显著性。

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