查询词典 tumor

Wilms" tumor is one of the most common solid tumors in children, and the genesis of Wilms" tumor is believed to be associated with delayed differentiation of metanephric blastema in fetus and retaining proliferation in postnatal period.

肾母细胞瘤（Wilms tumor， WT）是儿童最常见的实体瘤之一，其发病与后肾胚基细胞分化受阻并在出生后继续增殖有关。

Object In this study , we evaluated the tumor necrosis factor-α levels and lactate dehydrogenase of cerebrospinal fluid in patients with meningitis.

目的 研究肿瘤坏死因子-α(tumor necrosis factor-alpha，TNF-α)和乳酸脱氢酶(lactate dehydrogenase，LDH)在脑膜炎患者脑脊液(cerebrospinal fluid，CSF)中的含量，探讨它们在脑膜炎诊断中的临床意义。

Giant cell tumor of bone is a kind of common bone tumor,which has characteristics of high recurrence rate and invasion.recently,tumor vessel angiogenesis has been the warm spot of research.genesis,development and metabasis of solid tumor have close relationship with tumor vessel angiogenesis; extracellular matrix degradation is the key point for tumorous infiltration and metabasis;the significant biology characteristic of tumor cell is the disorder of tumor cell differentiation and apoptosis.the correlated research has very important significance for judging gct prognosis and guiding therapy.

骨巨细胞瘤（giant cell tumor of bone，gct）是一种常见骨肿瘤，由于其高复发率和强侵袭性，备受临床骨科工作者的关注。骨巨细胞瘤血管生成是近年来研究热点，实体瘤的发生、发展及转移与肿瘤的血管生成密切相关；细胞外基质降解在肿瘤的浸润和转移中起到关键作用；肿瘤细胞的分化凋亡障碍与无限增殖能力是肿瘤细胞的重要生物学特征。骨巨细胞瘤生物大分子研究的不断深化对判断gct的预后及指导治疗有重要意义。

Methylation is negative correlation with genetic transcription , and the mechanism is probably as follows : directly interfere the combination of specific transcripton and recognition site of each promoter ; mediated transcription inhibition by change the construction of chromatin; induced gene silencing by combination of methylation site and transcription inhibition. P16 gene is also called multiple tumor supresser gene , which is the best easily to methylate in the anti-oncogenes. P16 gene locates in 9p21 of mankind-chromatosome , and it's total length is 8.5kb .

甲基化与基因转录呈负相关，其机制可能是[3]：直接干扰特异的转录子和各自启动子识别位点的结合；通过改变染色质结构，介导转录抑制；甲基化DNA位点直接与转录抑制子结合，诱导基因沉默。p16基因又称为多肿瘤抑制基因( multiple tumor suppressor 1 ，MTS1) [4] ，是肺癌中最易发生甲基化的抑癌基因，该基因位于人类染色体9p21上，全长8.5kb ，由两个内含子和三个外显子组成。

Both Wilms' tumor in adults and polycythemia in Wilms' tumor are rare.

威尔斯氏肿瘤（Wilm's tumor）在成人是罕见的，红血球过多正在威尔斯氏肿瘤也是罕见的表现。

Objective A teratology study of tumor necrosis factor was conducted in mice.

目的 了解肿瘤坏死因子(tumor necrosis factor ，TNF)的致畸作用和胚胎毒性。

Giant cell tumor of bone is a kind of common bone tumor,which has characteristics of high recurrence rate and invasion.Recently,tumor vessel angiogenesis has been the warm spot of research.

骨巨细胞瘤（giant cell tumor of bone，GCT）是一种常见骨肿瘤，由于其高复发率和强侵袭性，备受临床骨科工作者的关注。

Aside from pancreatic enzymes activiation and autodigestive process, recent investigations have established that the upregulation of inflammatory mediator are believed to be the critical steps in the progression of mild pancreatitis to severe pancreatitis. Tumor necrosis factor-, ThyomboxaneA2 ,ProstaglandinsI2 are all important inflammatory mediator. TNF-( is one of cytokines. It is important to the over-production of ICAM-1,VCAM-1, TXA2 andPGI2. The ICAM-1 and VCAM-1 mediate both leukocytes adhesion and migration through the endothelium into tissues to connect with injuried target cells. The TXA2 and PGI2 are the production of arachidonic acid. They are responsible for the tissue ischaemia.

肿瘤坏死因子（Tumor necrosis factor-， TNF-、血栓素A2（ThyomboxaneA2，TXA2），前列环素（ProstaglandinsI2，PGI2）均是炎症反应中重要的炎性介质，其中肿瘤坏死因子-是非常重要的细胞因子之一，它由活化的单核细胞产生，在细胞间黏附分子（Intercellular adhesion molecule-1，ICAM-1）及血管细胞黏附分子(Vascular cell adhesion molecule-1，VCAM-1的表达、血栓素A2及前列环素过量生成方面起着重要的作用，前两者是介导白细胞与内皮细胞黏附，迁移于组织并与受损的靶细胞相结合的主要媒介，是炎症反应中的重要介质，后两者是花生四烯酸的代谢产物，亦是重要的炎性介质，参与构成血液循环障碍。

Barometz. The following factors were determined: blood rheology indexes in mouse, weight of mouse and their organs' weight, turgenscence of the feet of mouse, content of trace elements in blood in mouse, content of Interleukin-1β(IL-1β) and tumor necrosis factor in the joint fluid in mouse.

对以下指标进行测试：大鼠的血液流变学指标，大鼠的体重；大鼠的脏器重量；大鼠的足跖肿胀程度；大鼠的血中微量元素含量；大鼠关节腔炎症介质白细胞介素-1β(Interleukin.1β，IL-1β)和肿瘤坏死因子(tumor necrosis factor，TNF-α)的含量。

ABSTRACT Objective To discuss the clinical pathologic features and differential diagnosis of mixed germ cell sex cord stromal tumorwith malignant variant of germ cell tumor Methods The clinical pathologic datum and immunophenotype were studied in the case of ovary MGCSCST with malignant variance of germ cell tumor Results The patient's genital anatomy and female phenotype were normal,karotypes was 46xx with uterogestation The tumor tissue consisted of mixed germ cells and sex cord stromal cells with evident malignancy of mixed germ cells There was no atypical structure of gonadoblastoma in tumor tissue Conclusion MGCSCSST has complex morphosis,thus,to prevent misdiagnosis,more samples should be collected and more slices be cut The patient may have prognosis malo when there are high malignant variants of mixed germ cells in tumor tissue

目的 探讨混合性生殖细胞性索间质肿瘤(mixed germ cell sex cord stromal tumor，MGCSCST)伴恶性生殖细胞肿瘤变异型的临床病理特点及鉴别诊断。方法卵巢MGCSCST伴恶性生殖细胞肿瘤变异型的病例进行临床病理特征和免疫表型分析。结果患者生殖器的解剖结构和女性表型正常，染色体组型是46xx，足月妊娠。肿瘤组织由混合性生殖细胞和性索间质肿瘤构成，混合性生殖细胞有显著的恶性特征。瘤组织中没有典型的性腺母细胞瘤结构。结论 MGCSCST有复杂的形态结构，因此更多的取材和切片可以防止误诊，当肿瘤组织中的混合性生殖细胞有高度恶性变异时，患者预后不良。卵巢肿瘤；生殖细胞性索间质肿瘤；免疫组织化学

Graf, without question, is the greatest women's player in history.

格拉芙，现在，毫无疑问是女子网坛历史上最伟大的选手。

If not, you will have to look around at all your important data.

如果没有，您将需要检查所有的重要数据。