查询词典 toxicological

Objective To establish a database for biological and electrocardiographic parameters of Beagle dogs used for pharmacological and toxicological studies.

目的 测定正常Beagle犬生理指标，比较不同性别间各参数的差异，以建立健康成年Beagle犬相关生理学参数的基础正常值。

SM6 and SM7 of uncrystal were analyzed through GC-MS, the results showedthat SM6 main contained unsaturated fatty aldehyde with fragrance, i.e.-2,4-decadienal(58%), tetradecanoic acid (55.78%), 2-decenal(50%), Phthalic acid isobutylundecyl ester(47%), 2, 4-Decadienal(41%), 2-Undecenal (31%), 2-Methyl-Z,Z-3, 13-octadecadi-enol(18.84%), and SM7 contained saturation alkanes, i.e. 1, 2-Benzenedicarboxylic acid, butyl cyclohexyl ester(23.90%), Triacontane(22.63%),Nonacosane(21.04%), Heptadecane(18.84%), Octacosane(13.58%). Toxicological experiments were done to insure the pigment safety.

并对紫红丝膜菌色素非晶体部分的黄色油状物SM6和紫色粉末物SM7作了GC-MS分析，结果显示SM6中主要为具有香气成分的不饱和脂肪醛，其中含量较高的依次为：-2，4-癸二烯醛(58％)、十四烷酸(55.78％)、2-癸烯醛(50％)、邻苯二甲酸异丁基十一烷酯(47％)、2，4-癸二烯(41％)、2-十一碳烯醛(31％)、2-甲基-Z，Z-3，13-十八碳二烯酸(18.45％)等；SM7中主要为饱和直链烷烃，其中含量较高的依次为：1，2-苯二羧酸丁基环己酯(23.90％)、三十烷(22.63％)、二十九烷(21.04％)、十七烷(18.84％)、二十八烷(13.58％)。

The compound 103-1 is investigated in synthesis method, structure analysis, herbicidal activity, crop safety and toxicological test.

第五章是对优选化合物进行系统研究，以明确优选化合物的实际应用前景。

Recent research studies include trace-level analyses of polybrominated biphenyl ethers, perfluorochemicals, heavy metals such as mercury and hydrobiological toxicological studies.

在苏州市政府、中国科技大学、香港城市大学的大力支持下，实验室经过两年的努力，目前已拥有大中型化学分析仪器50余台套，占地面积2000平方米。

It was found that the toxic organic pollutants in Yangtze River could result into the toxicological effects on human's hepatic, reproductive, respiratory, incretionary, neural, immune and hematic system.

这些微量有机污染物可以损伤人体肝脏、发育、生殖、呼吸、内分泌、神经、免疫、血液等组织器官和系统的功能。

Results Free MMC 0.15625～5.0μg/kg significantly increased the positive rate of PCE micronuclear test, the chromosome aberration rate and rat teratogenecity, but the mitomycine C absorbed onto ACNP did not increased these heredity and proliferation toxicological indexes in a dose range of 0.625～10.0μg/kg.

结果 游离丝裂霉素腹腔注射0.15625～2.5μg/kg 均可导致小鼠骨髓微核试验阳性率和CHL染色体畸变率，用纳米活性炭吸附MMC后给药，在0.625～20.0μg/kg 腹腔注射后都没有明显增加微核试验阳性率和染色体畸变率。

With simple calculation procedure and results easy to explain,statistics momental analysis method has potential toxicological significance in kinetics study.

因其计算方便且结果易于解释，矩分析法在动力学研究中具有潜在的意义。

Pellar TC%Fuciarelli AF%Ejnik JW Distribution of uranium in rats implanted with depleted uranium pellets 10.1093/toxsci/49.1.29 Toxicological Sciences , 1999,1

李蓉%艾国平%徐辉%任泂%楼淑芬%程天民%粟永萍%郑怀恩%蒋建新%黄跃生吸入贫铀粉尘和/或嵌入贫铀片大鼠体内铀的分布第四军医大学学报， 2004，6

METHODS: We have employed a series of toxicological and pharmacodynamical tests to determine its LD50 and learn the actions of different prescriptions of Yumasha-fen's gradients.

进行LD50测定、小鼠酚红法、青蛙纤毛运动法、小鼠氨水引咳法、组织对豚鼠鼻粘膜过敏反应等毒理学和药效学试验，对各组份进行配方分析。

Reactive oxygen species causing DNA oxidative damage comes from two kinds of ways:one is from cellular normal physiological metabolism;the other is from outer environment.Redox-sensitive green fluorescent protein was expressed in Saccharomyces cerevisiae.Recombinant cells were evaluated in monitoring the changes in the redox state of living cells when challenged with toxicologically relevant metal ions NaAsO_2 or Pb(NO_3)_2 by measuring emission intensity at 510 nm with a Hitachi F6500 fluorescence spectrophotometer,roGFP expressed in yeast responded not only to typical membrane-permeant oxidants H_2O_2 and reductants DTT,but also to toxicological metal ion-induced intracellular redox changes in a dose-dependent manner.Moreover,exposure of yeast cells to NaAsO_2 or Pb(NO_3)_2 at concentrations that induced redox changes reported by roGFP caused up to 2～3 fold increases in DNA mutation frequency.This mutagenic effect was largely caused by oxidative stress since blocking the production of hydryl radicals with thiourea significantly reduced the mutation rate as well as delayed the cell death.

本文将对氧化还原状态变化敏感的绿色荧光蛋白roGFP1-R12，在酵母细胞中实现了多拷贝强表达；荧光扫描经强氧化剂H_2O_2和还原剂DTT以及环境中重金属NaAsO_2或Pb(NO_3)_2处理后的酵母细胞悬液，测定510 nm处的荧光发射强度结果显示，表达的绿色荧光蛋白对氧化还原水平敏感，且在510 nm处的荧光强度与一定的重金属浓度呈正相关，即roGFP1-R12在510nm处的荧光发射值随重金属浓度的增高而增强，从而说明重金属对细胞的毒性在一定程度上很可能是通过破坏细胞内的氧化还原平衡发生作用；同时通过该绿色荧光蛋白对胞内氧化还原状态变化的响应情况可以来实时检测环境中的重金属；遗传学的点突变频率及致死率实验数据表明，重金属能导致菌体的点突变频率和致死率升高，且活性氧的清除剂巯基脲能明显降低这种点突变和致死率，说明由重金属引发的这种点突变和致死效应在很大程度上是依赖于重金属对细胞诱导产生的氧化胁迫。

Methods: Five patients with parkinsonism or dystonia were assigned to general anesthesia using an modified endotracheal tube.

本实验依照人体实验之相关规定进行，五位患有帕金森氏症或肌张力异常的病人接受神经立体定位手术。

If you can benefit from this book, it is our honour.

如果您能从本书获益，这将是我们的荣幸。