查询词典 suppressor

The article focuses on the aberrant expression and significances of proto-oncogenes, tumor suppressor genes and genes associated with the proliferation process of gastric cells such as telomerase, transcription factor and cyclooxygenase, etc. These genes, alone or synergically, participate in gastric cancer cell proliferation, resulting in an uncontrolled growth characterized by over-proliferation of decreased apoptosis of gastric cancer cells.

本文着重阐述了与胃癌细胞增殖过程密切相关的端粒酶、核转录因子、环氧化酶等基因以及参与细胞周期调控的原癌基因、抑癌基因的异常表达及临床意义，这些基因或单独作用，或相互协同，参与胃癌细胞的增殖，使肿瘤细胞生长以增殖过多、凋亡过少的失控性生长为特征。

In summary, the BRD7 gene acted as a candidate of tumor suppressor gene with NPC. The overexpression of BRD7 can partly reverse malignant phenotype of NPC cell line. The suppression effect of BRD7 on NPC tumorigenesis my be achieved by recognizing acetylated histone peptide through their motif-bromodomain, then modulating gene transcription by taking part in histone acetylating and chromosome remodeling, finally influencing signal-transduction pathways.

综上所述，BRD7基因作为一个重要的鼻咽癌抑瘤基因侯选者，在鼻咽癌细胞中的过表达后，可导致鼻咽癌细胞 HNE蛋白质表达谱发生改变，逆转其恶性表型，其作用机理可能是：BRD7基因通过其功能域彭聪硕士学位论文10Bromodomain与乙酚化的组蛋白特异性结合，参于染色体的乙酚化，染色质的组装，从而影响基因转录的调控，最终影响细胞内的信号传导通路并实现对细胞周期的调控，从而发挥抑制鼻咽癌细胞生长的作用。

UPP can degrade intraeellular proteins with high effect and selectivity, especially for cell cycle regulated proteins, oncoproteins, tumor suppressor proteins, and denaturalized proteins.

当泛素-蛋白酶体系统对靶蛋白的降解功能失常时，可以引起癌蛋白聚集、抑癌蛋白异常降解、突变细胞凋亡受阻和增殖加速，从而导致肿瘤的发生。

Experiments in mice show that goosing one important tumor suppressor gene, p53, so it's a little bit activated all the time, does certainly hold off cancer ...

这就可能造成相邻的细胞和组织发炎，而炎症又有可能引发许多与衰老有关的疾病也包括一些老年性癌症。

Objective To improve the construction of adenovirus expression vector harbouring widetype tumor suppressor gene PTEN.

目的 为改进构建野生型抑癌基因PTEN重组腺病毒表达载体的方法。

Now an international group of researchers has found at least one reason why. BRCA1 inactivates a tumor suppressor gene known as PTEN.

现在一个国际性的研究团队发现这是由于BRCA1抑制了PTEN的结果，而PTEN是一个抑癌基因。

Now an international group of researchers has found at least one reason why. BRCA1 inactivates a tumor suppressor gene known as PTEN.

现今一支国际研究小组发现原因之一是BRCA1会抑制另一种名为PTEN的基因，而PTEN基因是人体内抑制肿瘤的基因。

During this process, the genetic alteration includes the activating of oncogenes and inactivating of tumor suppressor genes.

在这个过程中，存在着癌基因的激活和抑癌基因的失活等一系列的遗传学改变。

So inactivating of tumor suppressor genes is a critical event to lung cancer pathogenesis.

因此抑癌基因的失活在多种癌变过程中起着重要的作用。

The inactivating of tumor suppressor genes is a critical event to the cancer pathogenesis.

抑癌基因的失活在肿瘤发生中的作用至关重要。

The small blue capacitor has very high chances to go fully shorted compare to electrolytic capacitor which is very rare.

小蓝电容器具有很高的机会去充分地缩短了比较电解电容器，这是非常罕见的。

In the Italian campaigns of 1513 and 1515, when the Swiss won the victories of Novara and Marignan, he acted as army chaplain.

在意大利的运动， 1513年和1515年，当瑞士赢得了胜利，诺瓦拉和marignan ，他担任军队的牧师。