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The mutagenicity of seed powder and seed oil of transgenic CryIA cotton to mammals and fish was evaluated in this study. The raw cotton seed powder or seed oil was mixed into mice and fish's diet. Cyclophosphamide and NaF were used as positive controls respectively. Regular cotton seed powder and seed oil were used as negative controls. The micronucleus frequency in mice bone marrow polychromatic erythrocytes and in eripheral erythrocytes of Zebrafish were assayed in this study. The sperm malformation rate in mice was also investigated.

摘 要：分别以环磷酰胺和氟化钠作为阳性诱变剂，以普通棉的棉籽粉及棉籽油作为对照物，同时设阴性对照组，以成年封闭群昆明种雄性小鼠和斑马鱼为实验材料，将棉籽粉或棉籽油掺入饲料中饲喂小鼠或斑马鱼，检测小鼠骨髓嗜多染红细胞（Polychromatic erythrocytes， PCE）微核率（Micronucleus frequency， MN‰）和精子畸变率，以及斑马鱼外周血红细胞微核率。

The mutagenicity of seed powder and seed oil of transgenic CryIA cotton to mammals and fish was evaluated in this study. The raw cotton seed powder or seed oil was mixed into mice and fish's diet. Cyclophosphamide and NaF were used as positive controls respectively. Regular cotton seed powder and seed oil were used as negative controls. The micronucleus frequency in mice bone marrow polychromatic erythrocytes and in eripheral erythrocytes of Zebrafishwere assayed in this study. The sperm malformation rate in mice was also investigated.

分别以环磷酰胺和氟化钠作为阳性诱变剂，以普通棉的棉籽粉及棉籽油作为对照物，同时设阴性对照组，以成年封闭群昆明种雄性小鼠和斑马鱼为实验材料，将棉籽粉或棉籽油掺入饲料中饲喂小鼠或斑马鱼，检测小鼠骨髓嗜多染红细胞（Polychromatic erythrocytes， PCE）微核率（Micronucleus frequency，MN‰）和精子畸变率，以及斑马鱼外周血红细胞微核率。

China introduced TQM at the end of 1970s to improve the quality of its industry product but did not make enough progress because the project was impelled by the administration. Since the year of 2000s, monopoly in Chinese seed industry has been broken down and the market is growing rapidly, seed company are facing serious competition both from the inner and the outer so it is in urgent need of improving seed quality and competitive power. Under such conditions, this paper made a study on the feasibility of improving the seed quality and management level of Chinese seed industry by introducing TQM, and hope the research conclusion will be useful to the development of Chinese seed industry.

中国在七十年代末期也开始引入TQM来改善我们的工业产品品质，但是在行政力量推动下的质量运动最后大多无疾而终，效果大打折扣。2000年以来，中国种子行业行政垄断被打破，市场化进程加快，种子公司面临着来自国内外激烈的竞争，亟须提高种子质量，提高自己的竞争力，在这种情况下，笔者对中国种业引入TQM来提升种子质量和管理水平的可行性进行了探讨和研究，希望本文的结论对中国种业的发展有一定的参考意义。

Engages itself in dealing in Chinese herbal medicines, such as the Chinese caterpillar fungus, Rhubarb, red orpin, snow lotus, etc., a series of honey products like fresh royal jelly, frozen jelly powder, honey, pollen, bee glue, etc., and sea buckthorn fruit powder, extracted oil, condensed juice, etc., and a series of healthcare products, including Cordyceps oral medication, capsule, Rhubarb granule, Hongxuedongxia pill, sea buckthorn capsule, bee glue capsule and frozen jelly powder capsule, etc.

产品特点：青海新铠实业有限公司以青藏高原独特的自然资源为依托，主营冬虫夏草、大黄、红景天、雪莲花等中药材；蜂王浆、蜂王浆冻干粉、蜂蜜、花粉、蜂胶等蜂产品；沙棘果粉、沙棘油、浓缩汁等沙棘制品以及虫草口服液、虫草胶囊、大黄颗粒、红雪冬夏片、沙棘粉胶囊、蜂胶胶囊、蜂王浆冻干粉胶囊等保健制品。

The patients were at random divided as yizhi capsule group (47 cases) and control group (47 cases)METHODS: Medicine for patients in the yizhi capsule group: Yizhi capsule, made from processed flowery knotweed 14 g, ginseng 4 g, acorus 8 g,polygala 6 g, leech 10 g, epimedium 10 g, anemarrhena 6 g, ligasticum 12g, with each capsule contenting 0.228 g, which was consistent with 10 g raw drug, orally, 6 capsules, 3 time a day.

随机分为益智胶囊组47例和对照组47例。方法：益智胶囊组用药：益智胶囊成分为制何首乌14 g，人参4 g，石菖蒲8 g，远志6 g，水蛭10 g，淫羊藿10 g，知母6 g，川芎12 g，每粒胶囊含内容物0.228 g，相当于生药10 g.6粒/次，3次/d，口服。

This declared 40 websites are specific include Chinese medical university accessary and infecund not He Qirui of capsule of treasure of pregnant of luck of Qi of sale of Yo research center (www.2008sbb.com/) gives birth to capsule of essence of life, claim to treat infecund not Yo;(www.999qlx.com/) of research center of Asia-Pacific reproduction medicine sells capsule of Tai of accept rice front row, claim to treat male disease; Chinese traditional Chinese medical science is advanced medical academy splash grinds only central (www.seban886.com) sells capsule of Jiang Xiaoqu spot, claim to treat splash;(www.gegd.com.cn/) of office of project of deliverance of prevention and cure of Chinese second Gan sells second Gan spirit to condense bolus, claim to treat second Gan;(www.000120.com/) of center of rehabilitation of psoriasis of academy of China international dermatosis sells Tai of tinea of golden Chan ·, claim to treat skin disease;(www.gjpf.com/) of research center of psoriasis of academy of gene of China International dermatosis sells peace of bits of beneficial kidney dispel, claim to treat skin disease; Science of international Yi medicine grinds only in pancreas of candy of jewellery of sale of (www.tnb518.com/) of center of treatment of disease of make water of total courtyard sugar is peaceful, claim to treat disease of sugar make water; Disease of blood-vessel of international Xin head studies hypertension of total meeting China is ill stabilized voltage of sale of research center (www.120gxy.cn/) originallies this bolus, claim to treat hypertension;(www.zky666.com/) of courtyard of scientific research of ill project of bone of medicine of Chinese traditional Chinese medical science sells powerful force to put in red of dragon bones and muscles 's charge, claim to treat rigidity Xing rachitis to wait.

这次公告的40家网站具体包括中国医科大学附属不孕不育研究中心(www.2008sbb.com/)销售麒瑞孕宝胶囊和麒瑞生精胶囊，声称治疗不孕不育；亚太生殖医学研究中心(www.999qlx.com/)销售纳米前列肽胶囊，声称治疗男性疾病；中国中医高等医学研究院色斑专研中心(www.seban886.com)销售强效祛斑胶囊，声称治疗色斑；中国乙肝防治救助工程办公室(www.gegd.com.cn/)销售乙肝灵浓缩丸，声称治疗乙肝；中华国际皮肤病研究院银屑病康复中心(www.000120.com/)销售金蟾·癣肽，声称治疗皮肤病；中国国际皮肤病基因研究院牛皮癣研究中心(www.gjpf.com/)销售益肾祛屑宁，声称治疗皮肤病；中研国际医药科学专研总院糖尿病治疗中心(www.tnb518.com/)销售珍宝糖胰宁，声称治疗糖尿病；国际心脑血管病研究总会中国高血压病研究中心(www.120gxy.cn/)销售稳压固本丸，声称治疗高血压；中国中医药骨病工程科研院(www.zky666.com/)销售强力归龙筋骨丹，声称治疗强直性脊柱炎等。

At the same time for all kinds of snake venom lyophilized powder, fresh gall bladder, do gall bladder,±, snake powder, snake oil, live snakes, frozen snake, snakes do, acutus wine, liquor±, viper wine, snake wine, snake powder capsule, powder Shedan, Snake Oil Soft Capsule, recreation Capsule, Capsule Oolong, snakes ointment, Dongchuang Unguentum, Shedan SOD Honey, Honey SOD snake oil, disinfectant spray, snake leather, snake handbags, snake package with products such as snake skin, forming from the aquaculture, processing and selling one-stop service system.

同时可供各种蛇毒冻干粉、鲜蛇胆、干蛇胆、蛇鞭、蛇粉、蛇油、活蛇、冻蛇、蛇干、五步蛇酒、蛇鞭酒、蝮蛇酒、蛇胆酒、蛇粉胶囊、蛇胆粉胶囊、蛇油软胶囊、康乐宝胶囊、乌龙宝胶囊、蛇油膏、冻疮膏、蛇胆SOD蜜、蛇油SOD蜜、消毒喷剂、蛇皮革、蛇皮包、蛇包带等蛇皮工艺制品，形成从养殖、加工到销售一条龙服务体系。

Methods ①anti-inflammatory trial: 40 rats were randomly divided into control group, high-dose bushenlizhuo capsule group, middle-dose bushenlizhuo capsule group and low-dose bushenlizhuo capsule group(10 rats in each group).the rats in control group were given distilled water, and the rats in experimental groups were given different doses of capsule（4.0、2.0、1.0g/kg）, then enhance the capillary permeability of abdominal skin of rats by using xylic acid,and the od numerical value was detected.

(1)抗炎实验：将40只小鼠随机分为补肾利浊胶囊高、中、低剂量组及对照组各10只，补肾利浊胶囊高、中、低剂量组分别给予相应剂量的补肾利浊胶囊(分别为4.0、2.0、1.0 g/kg)，对照组给予蒸馏水，采用二甲苯酸致小鼠腹部皮肤毛细血管通透性增高，测定光密度值；(2)镇痛实验：40只小鼠分组及给药同抗炎实验，采用腹腔注射醋酸致小鼠出现扭体反应，纪录扭体次数并计算镇痛百分率；(3)抗前列腺炎实验：将雄性大鼠50只随机分为补肾利浊胶囊高、中、低剂量组及模型对照组及正常对照组，各10只。

Engages itself in dealing in Chinese herbal medicines, such as the Chinese caterpillar fungus, Rhubarb, red orpin, snow lotus, etc., a series of honey products like fresh royal jelly, frozen jelly powder, honey, pollen, bee glue, etc., and sea buckthorn fruit powder, extracted oil, condensed juice, etc., and a series of healthcare products, including Cordyceps oral medication, capsule, Rhubarb granule, Hongxuedongxia pill, sea buckthorn capsule, bee glue capsule and frozen jelly powder capsule, etc.

产品介绍：青海新铠实业有限公司以青藏高原独特的自然资源为依托，主营冬虫夏草、大黄、红景天、雪莲花等中药材；蜂王浆、蜂王浆冻干粉、蜂蜜、花粉、蜂胶等蜂产品；沙棘果粉、沙棘油、浓缩汁等沙棘制品以及虫草口服液、虫草胶囊、大黄颗粒、红雪冬夏片、沙棘粉胶囊、蜂胶胶囊、蜂王浆冻干粉胶囊等保健制品。

Health food shop can produce a hard capsule, soft capsule, tablet, powder, tea agent, granules, preparation of wine, drinks, etc., and the introduction of advanced automatic liquid France Capsule Filling Machine and sealing machine, will be filled with oil-soluble materials to hard Capsule play better absorption and utilization value of effective products improve the safety of stability and preservation of moisture.

保健品车间可生产硬胶囊、软胶囊、片剂、粉剂、茶剂、冲剂、配制酒、饮料等，并引进先进的法国全自动液体硬胶囊充填机及封口机，将油溶性原料填充至硬胶囊中，发挥更好的吸收利用价值，有效提高产品的安全稳定度及防潮保存性。

Among which is the mindset, perceptions and moralities of those who accept mini- military tasks for economic gains.

其中最重要的是心态，观念和道德的人谁接受小型军事任务的经济收益。

In time course imaging, activity peaked 2 days after coronary ligation.

在时程成像检测，活性峰值在冠脉结扎后2天。