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The study, led by Benjamin Alman from the Hospital For Sick Children, Toronto, investigated the role of the beta-catenin signaling pathway, which activates T cell factor -dependent gene transcription, and which is known to have a key regulatory role in embryonic skeletal development.

这一研究的主要负责人是来自加拿大多伦多儿童医院的Benjamin Alman，他的小组主要研究了beta-catenin信号路径的作用，这一分子信号主要负责激活和T细胞因子相关的基因转录，而科学家们已经知道以上这一激活过程对于胚胎期间的骨骼形成起着关键的调控作用。

The study, led by Benjamin Alman from the Hospital For Sick Children, Toronto, inestigated the role of the β-catenin signaling pathway, which actiates T cell factor -dependent gene transcription, and which is known to hae a key regulatory role in embryonic skeletal deelopment.

这项由来自多伦多儿童医院（Hospital For Sick Children？）的Benjamin Alman领导的研究调查了β连环蛋白信号通路的作用，这条通路能激活T细胞因子依赖的基因转录，并且被发现在胚胎骨骼发育中起关键作用。

DCs acquired by our reformed methods express both CD83 and CD 14 molecules highly, and have a higher density than other domestic reports. The higher TNF in DCs culture medium of HC patient suggests DCs in patient still have antigen presenting ability and by optimization the culture medium would improve its presenting ability and have a potential value in design and application individual vaccine. Although antigens pulsed DCs have a decrescent antigen presenting ability but BCG HSP70 could induce its mature and improve its presenting ability. Suggests BCG HSP70 would be a useful mature inducer. Lymphocytes primed by DCs based HC vaccine have the specific cytotoxicity against HCC lines. The CTL after freezing and anabiotic could prophylaxis and therapy HC xenograft on nude mouse. The results also suggests that CD4〓 lymphocytes play a important role in HC with a good differentiation and would be useful in treatment this kind of HC. After being activated by Peptide LLNQHACAV of hAFP and apoptotic HCCs pulsed DCs respectively, the culture medium of activated lymphocytes both contains a high level Th1 cytokines IL-12 and TNF. Primed lymphocytes appeared a characteristic of NK cells. DCs not only inhibited the growth of human HCC and other cancer cells in vitro but also prevented the growth of HC xenograft on nude mouse in vivo. There are at least three kinds of mechanism playing important role in DC based vaccine ,there are inhibition of DCs, HC specific CTL and cytokines pathway.

诱导出的DC共同表达CD83和CD14分子，CD83分子表达明显高于国内报道；肝癌患者DC培养上清中TNF水平高于健康人，提示肝癌患者DC仍具一定的抗原呈递能力，适当调控可使其行使APC功能，以期在肝癌个体化疫苗中发挥作用；DC负载肝癌可溶性抗原后，抗原呈递能力降低，BCG HSP70可促进DC成熟，增加其抗原呈递能力，预示BCG HSP70有可能成为促进DC活化和成熟的另一重要分子；肝癌DC疫苗在体外诱导肝癌特异性淋巴细胞，活化的淋巴细胞在体外对肝癌细胞的杀伤以特异性CTL为主，同时分泌较高水平Th1型细胞因子IL-12和TNF，并抑制4种肝癌细胞生长；冷冻复苏后的肝癌特异性淋巴细胞可以预防和抑制人肝癌裸鼠皮下移植瘤，提示DC负载肝癌可溶性抗原后诱发的MHC-Ⅱ类限制性CD4〓T细胞有可能在分化程度高的肝癌治疗中发挥作用；用DC和HLA-A2〓DC分别负载凋亡肝癌细胞和hAFP218-226位LLNQHACAV HLA-A2限制性九肽，在体外诱导肝癌特异性淋巴细胞，活化后的CTL细胞分泌较高水平的Th1型细胞因子IL-12和TNF，并具较强杀伤活性，此CTL同时具备NK细胞特征；DC对肿瘤细胞的抑制作用可能是通过吞噬实现的，Fas-L在DC抑制中也起一定作用；DC对人肝癌裸鼠皮下移植瘤的抑制率为97％；在肝癌DC疫苗的作用中，至少联合3种以上机制，即通过DC的直接作用、肝癌特异性CTL和细胞因子途径直接或间接地杀伤和抑制肝癌细胞。

Through this issue, we found that with 2% NaOH-NALC digested within 10 minutes in the rapid decomposition of the viscous sputum, in ensuring the effectiveness of digestion at the same time not too much because of the role of NaOH to kill bacteria (time to 20 minutes), and would not affect the role of magnetic particles; quantitative simulation of self-made through the application of clinical samples, we compared the acid-fast stain and auramine O staining of the detection limit, auramine O fluorescence staining against the backdrop of a clear dark green light acid-fast stain of Mycobacterium tuberculosis than the white background of the red eye-catching TB is more capacity, auramine O staining in the detection limit of 0.05 to 0.001 between Maxwell, higher than the acid-fast stain of Michael's 0.05 units, The former is more sensitive; In addition, the accumulation of magnetic nanoparticles of the samples after the smear, in the microscope show the number of TB was significantly higher than that of the specimens has not been enriched.

通过本次课题，我们发现用2%NaOH-NALC消化液可在10分钟内迅速裂解痰液的粘性介质，在保证消化效果的同时不会由于NaOH过强的作用杀死细菌（时间控制在20分钟内），亦不会影响磁性颗粒的作用；通过应用自制定量模拟临床标本，我们比较了抗酸染色和金胺O荧光染色的检出限，金胺O荧光染色黑暗背景下发出明显绿色亮光的结核杆菌较抗酸染色白色背景中的红色结核杆菌更容醒目，金胺O荧光染色的检出限在0.05~0.001个麦氏单位之间，高于抗酸染色的0.05个麦氏单位，前者敏感度较高；另外，经过磁性纳米颗粒富集作用后的标本涂片，在镜下显示其结核杆菌数量明显高于未经过富集的标本。

The researcher also suggests that we design courses on education and guidance with the use of books to build an open discussion space in order to adjust students'cognition on sex role, establish the multicultural values. The sex education of teachers and parents should be enhanced at the same time. For future researches, the research objects and the selection of different materials can be enlarged, increase the research on bibliotherapeutic process and study on how parents, teachers, peer groups and mass media influence the sex role concept of the student.

本研究并建议在教育与辅导上可以利用书籍设计相关课程，营造一个开放的讨论空间来改变学生的性别角色认知，建立其多元文化的价值观，并且加强对教师以及父母的性别教育，此外建议在未来的研究上可以扩大研究对象以及不同媒材的选择，增加对读书治疗心理历程的研究，并探讨父母、教师、同侪、大众传播媒体如何影响学生的性别角色观。

And I also wonder it's have a strong body or fat body. Last, I found a strong body cacodemon seems it like battling. But if the cacodemon is over-fat seem lazy. I want to sharp a role who is having no interest to a war but is unconquerable role. In order not to be aggressive, I decide the lord of cacodemon is strong and fat.

于是我的角色开始在强壮和肥胖之间徘徊，我发现强壮的体型会显得比较好斗，而过于肥胖会显得慵懒，我们要的是一个对战争没有兴趣却无敌的角色，为了不表现过分的进攻性，于是决定这个恶魔领主是一个壮硕的胖子。。。

But from now on there are few reports about its role on organgenesis. So it will be very significative to study its role in cardiogenesis.

Geminin和cdt1的相互作用对细胞周期的调节非常重要，但到目前为止关于geminin对器官发育的影响的报道非常少。

(1) Morphological characteristics of CT play an important role in the diagnosis of cavitary lung diseases,but sometimes it is very difficult to identify the quality of cavitary lung diseases from the CT morphological characteristics of the cavity simply,the patient\'s gender has an important role.

(1)空洞的CT形态学特征对肺部空洞病变的诊断具有重要的作用，但有时单纯从空洞的CT形态学特征对肺部空洞病变的诊断很困难，患者性别、年龄对病变性质均有提示作用。

This has led to budget's double conflictive functions: forward-looking role in the allocation of resources and feedback evaluation role.

这导致预算具有矛盾的双重功能：前瞻性的资源配置功能和反馈式考核评价功能。

Sheng Shicai played a decisive role in modern history of Xinjiang, but he was a contestable history role at the same time.

盛世才是新疆近现代史上举足轻重的人物，也是一位颇具争议的历史人物。

Cable dampener cannot be rolled up but must be hung over the cable.

缆帆不能被卷起，必须保证处于展开状态

"This skylark is a present from my master," he says.

"这只云雀是我主人献上的礼物。"他说。