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The effects and mechanism of GABAergic neurons, NOergic neurons, opioid peptide and cyclic adenosine monophosphate in the nucleus reticularis thalami on sleep-wakefulness cycle of rats and the effects and mechanism of the 5-HTergic nerve fibers project from the nucleus raphes dorsalis to RT on sleep-wakefulness cycle of rats were investigated with the methods of brain stereotaxic, nucleus spile, microinjection and polysomngraphy.1. The effects of GABAergic neurons in RT on sleep-wakefulness cycle of rats1.1 Microinjection of 3-mercaptopropionic acid (3-MP, a kind of glutamate decarboxylase inhibitor) into RT. On the day of microinjection, sleep only decreased a litter. On the second day, sleep marked decreased and wakefulness marked increased. On the third and fourth day, sleep and wakefulness stages resumed to normal.1.2 Microinjection of gamma-amino butyric acid (GABA 1.0μg) into RT enhanced sleep and reduced wakefulness compared with control; while microinjection of L-glutamate (L-Glu, 0.2μg) decreased sleep and increased wakefulness; microinjection of bicuculline (BIC, 1.0μg), a GABAA receptor antagonist, enhanced wakefulness and reduced sleep; microinjection of baclofen (BAC, 1.0μg), GABAB receptor agonist, had the same effects as GABA.2. The effects of NOergic neurons in RT on sleep-wakefulness cycle of rats2.1 Microinjection of L-arginine (L-Arg, 0.5μg) into RT decreased sleep compared with control, but there were on statistaical difference between L-Arg group and control; while microinjection of sodium nitroprusside (SNP, 0.2μg), a NO donor into RT, sleep marked decreased and wakefulness marked increased. Microinjection of nitric oxide synthase inhibitor, N-nitro-L-arginine (L-NNA, 2.0μg) into RT enhanced sleep and reduced wakefulness.2.2 After simultaneous microinjection of L-NNA (2.0μg) and SNP (0.2μg) into RT, SNP abolished the sleep-promoting effect of L-NNA compared with L-NNA group; after simultaneous microinjection of L-NNA (2.0μg) and L-Arg(0.5μg) into RT, we found that L-NNA could not blocked the wakefulness-promoting effect of L-Arg.3. The effects of opioid peptide in RT on sleep-wakefulness cycle of rats3.1 Microinjection of morphine sulfate (MOR, 1.0μg) into RT increased wakefulness and decreased sleep compared with control; while microinjection of naloxone hydrochloride (NAL, 1.0μg), the antagonist of opiate receptors, into RT, enhanced sleep and reduced wakefulness.3.2 After simultaneous microinjection of MOR (1.0μg) and NAL (1.0μg) into RT, the wakefulness-promoting effect of MOR and the sleep-promoting effect of NAL were not observed compared with control.4. The effects of cAMP in RT on sleep-wakefulness cycle of rats Microinjection of cAMP (1.0μg) into RT increased sleep and decreased wakefulness compared with control; microinjection of methylene blue (MB,1.0μg) into RT enhanced sleep and reduced wakefulness compared with control.5. The effects of the 5-HTergic nerve fibers project from DRN to RT on sleep-wakefulness cycle of rats5.1 When L-Glu (0.2μg) was microinjected into DRN and normal sodium (NS,1.0μg) was microinjected into bilateral RT. We found that sleep was decreased and wakefulness was increased compared with control; when L-Glu (0.2μg) was microinjected into DRN and methysergide (MS,1.0μg), a non-selective 5-HT antagonist, was microinjected into bilateral RT, We found that sleep was enhanced and wakefulness was reduced compared with L-Glu group.5.2 When p-chlorophenylalanine (PCPA, 10μg) was microinjected into DRN and NS (1.0μg) was microinjected into bilateral RT, We found that sleep was increased and wakefulness was decreased compared with control; microinjection of 5-hydroxytryptaphan (5-HTP, 1.0μg), which can convert to 5-HT by the enzyme tryptophane hydroxylase and enhance 5-HT into bilateral RT, could block the effect of microinjection of PCPA into DRN on sleep-wakefulness cycle.

本研究采用脑立体定位、核团插管、微量注射、多导睡眠描记等方法,研究丘脑网状核(nucleus reticularis thalami,RT)中γ-氨基丁酸(gamma-amino butyric acid ,GABA)能神经元、一氧化氮(nitrogen monoxidum,NO)能神经元、阿片肽类神经递质、环一磷酸腺苷(cyclic adenosine monophosphate,cAMP)及中缝背核(nucleus raphes dorsalis,DRN)至RT的5-羟色胺(5-hydroxytryptamine,5-HT)能神经纤维投射对大鼠睡眠-觉醒周期的影响及其作用机制。1 RT内GABA能神经元对大鼠睡眠-觉醒周期的影响1.1大鼠RT内微量注射GABA合成关键酶抑制剂3-巯基丙酸(3-MP,5μg),注射当天睡眠时间略有减少,第二日睡眠时间显著减少,觉醒时间明显增多,第三、四日睡眠和觉醒时间逐渐恢复至正常。1.2大鼠RT内微量注射GABA受体激动剂GABA( 1.0μg)后,与生理盐水组比较,睡眠时间增加,觉醒时间减少;而RT内微量注射L-谷氨酸(glutamic acid, L-Glu, 0.2μg)后,睡眠时间减少,觉醒时间增加;RT内微量注射GABAA受体阻断剂荷包牡丹碱(bicuculline,BIC,1.0μg)后,睡眠时间减少,觉醒时间增加;RT内微量注射GABAB受体激动剂氯苯氨丁酸(baclofen,BAC,1.0μg)后,产生了与GABA相似的促睡眠效果。2 RT内NO能神经元对大鼠睡眠-觉醒周期的影响2.1大鼠RT内微量注射NO的前体L-精氨酸(L-Arg,0.5μg)后,与生理盐水组对比,睡眠时间略有减少,但无显著性意义;而RT内微量注射NO的供体硝普钠(Sodium Nitroprusside,SNP,0.2μg)后可明显增加觉醒时间,缩短睡眠时间;微量注射一氧化氮合酶抑制剂L-硝基精氨酸(L-arginine,L-NNA,2.0μg)后,引起睡眠时间增多,觉醒时间减少。2.2大鼠RT内同时微量注射L-NNA(2.0μg)和SNP(0.2μg)后与L-NNA组比较发现SNP逆转了L-NNA的促睡眠作用;RT内同时微量注射L-NNA(2.0μg)和L-Arg(0.5μg)后,与L-NNA(2.0μg)组比较发现L-Arg可以增加觉醒而缩短睡眠,其促觉醒作用未能被NOS的抑制剂L-NNA所逆转。3 RT内阿片肽对大鼠睡眠-觉醒周期的影响3.1大鼠RT内微量注射硫酸吗啡(morphine sulfate,MOR,1.0μg)后与生理盐水组对比,睡眠时间减少而觉醒时间增加; RT内微量注射阿片肽受体拮抗剂盐酸纳洛酮(naloxone hydrochloride,NAL,1.0μg)后与生理盐水组比较,睡眠时间增加而觉醒时间减少。3.2大鼠RT内同时微量注射MOR(1.0μg)和NAL(1.0μg)后,与生理盐水组对比,原有的MOR促觉醒效果和NAL的促睡眠效果都没有表现。4 RT内环一磷酸腺苷信使对大鼠睡眠-觉醒周期的影响大鼠RT内微量注射cAMP(1.0μg)后与NS(1.0μg)组比较,睡眠时间增多而觉醒时间减少;RT内微量注射亚甲蓝(methylene blue,MB,1.0μg)后,与NS组比较,睡眠时间增多而觉醒时间减少。5中缝背核投射到丘脑网状核的5-羟色胺能神经纤维对大鼠睡眠-觉醒周期的影响5.1大鼠DRN内微量注射L-Glu(0.2μg),同时在双侧RT内微量注射NS (1.0μg)后,与对照组(DRN和双侧RT注射NS, 0.2μg)比较,睡眠时间减少,觉醒时间增多;大鼠DRN内微量注射L-Glu(0.2μg),同时在双侧RT内微量注射二甲基麦角新碱(methysergide, MS, 1.0μg )后,与对照组(DRN注射L-Glu 0.2μg,双侧RT注射NS 1.0μg)比较,睡眠时间增多,觉醒时间减少。5.2大鼠DRN内微量注射对氯苯丙氨酸(p-chlorophenylalanine,PCPA,10μg),同时在双侧RT内微量注射NS (1.0μg)后,与对照组(DRN和双侧RT注射NS, 1.0μg)比较,睡眠时间增多,觉醒时间减少;大鼠DRN内微量注射PCPA(10μg),产生睡眠增多效应后,在双侧RT内微量注射5-羟色胺酸(5-hydroxytryptaphan , 5-HTP, 1.0μg )后,与对照组(DRN注射PCPA 10μg,双侧RT注射NS 1.0μg)比较,睡眠时间减少,觉醒时间增多。

Intermediate heat cycle can be reduced because the tail blade turbine steam humidity and reduce steam consumption. improve plant efficiency and thermal cycling in the unit were popular, however, Reheat temperature control system with nonlinear their targets, inertia, the characteristics of delay, Power Plant to become more difficult to control the system-paper fuzzy control theory and fuzzy logic, reconsidered conventional PID control law on the basis of the study and intelligent fuzzy PID control, the 300MW units Reheat fuzzy control process using adaptive PID control, the introduction of load feedforward. design configuration, the final design complex adaptive feedforward cascade control system and MATLAB for simulation, simulation results show that the response speed, Robust control and accuracy, the system has considerable advantages Unit to improve the efficiency and reduce the operational workload.

中间再热循环技术因其可以降低汽轮机尾部叶片的蒸汽湿度和降低汽耗,提高电厂的热循环效率而在单元机组中被普遍采用,然而,再热气温控制系统因其对象具有非线性,大惯性,大迟延等特点,成为火电厂较难控制的系统之-,本文运用模糊控制理论和模糊逻辑推理,在重新认识常规PID控制规律的基础上探讨了PID与智能模糊控制相结合,在电厂300MW发电机组再热模糊控制过程中使用自适应PID控制,引入负荷前馈,设计组态,最终设计出自适应复合型前馈串级控制系统,并在MATLAB中进行仿真模拟,仿真结果表明,在响应速度,鲁棒性和控制精度等方面,此系统都具有相当大的优越性,有利于提高机组的效率和减轻运行人员的劳动负荷。

The mainly learnning is low-voltage apparatus、three phase asynchronous motor and electric control wiring of DC Motors、Principle and control of stepper motor and control wiring of typical electric machine、basic theory and basic methods of machine equipment electric control、 basic control circuit of electric control system、analysis of typical electric machine control System、basic principles and methods used of PLC、design and debug of machine tool control system、 design of electrical control gear etc.

主要学习常用低压电器、三相异步电动机和直流电动机的电气控制线路、步进电动机工作原理及控制以及典型机床电气控制线路、机床设备电气控制的基本理论和基本方法、电气控制系统的基本控制电路、典型机床电气控制系统分析、可编程序控制器的基本原理及使用方法、机床控制系统的设计和调试、电气控制装置设计等内容。

This invention provides a kind of microwave oven that can identify the metal cuisine container. It includes the rotary disk of the cooking room. In the electricity control room there is control circuit. In the control circuit there is main control slug which connects with the current source. Between the power of the control circuit and the main control slug there is alarm circuit and they form a loop with the control circuit. There set the conductive coat and standard riding line on the rotary disk. Through the conductive end set under the rotary disk that the rotary disk's standard riding line connects with, one conductive end connects with the power of the control circuit, and the other connects with the alarm loop and the main control slug.

本发明提供一种具有识别金属料理器皿功能的微波炉,包括有烹调室的旋转盘,电控室中设有控制电路,在控制电路中含有与电源连接的主控芯片,在控制电路的电源与主控芯片之间设置有报警电路并与控制电路形成回路;在旋转盘上设有导电涂层和标准安放线,通过旋转盘上的标准安放线连接设在旋转盘下方的导电端子,其中一导电端子与控制电路中电源相连,另一导电端子与报警电路和主控芯片相连接。

The development direction changed direction according to the four-wheeler, the domestic and international company changes direction organization to control to the four-wheeler currently main adoption of is a numeral control, this is owing to a lot of advantages of numerical control:the procedure turn a control, the controller carries on the processing of operation and numerical information according to the control regulation designed, mainly passing procedure to carry out, if change control regulation need to change software, but need not change the hardware structure of system: control the accuracy is high, in the emulation the control the system, the accuracy of the controller from the accuracy of the component but settle, numerical controller accuracy from word long decision;Stability good;The software replies to use, needing a hardware environment of using the homology realization in the emulation the system, the numerical controller is a procedure control, the sub- procedure mold piece which need to be designed and write to carry out its model, can immediately carry out several links of functions expediently.

目前各个厂家大多采用的是PLC、单片机应用于四轮转向控制器中,功能基本能够实现,相比较之下,信号处理能力较强的数字信号处理器各方面均性能优于以上三种处理器。DSP是新世纪数字化革命的核心。它是一种独特的微处理器,具有可编程性,且实时运行速度远远超过通用微处理器。强大的数据处理能力和高速的运行速度,是DSP最值得称道的两大特色。DSP芯片是一种特别适合进行数字信号处理的微处理器。它强调运算处理的实时性,因此除了具备普通微处理器所强调的高速运算和控制功能外,主要针对实时数字信号处理,在处理器结构、指令系统和数据流程上做了很大的改动。它具有灵活、精确、可靠性好、体积小、功耗低和易于大规模集成等优点。

The authors present fundamental principles of several APF control schemes based on DSP such as space vector modulation, hysteresis current control, monocyclic control, slide mode control, dead beat control, repetitive control, predictive control and ANN based control, and the respective merit and demeritof these control method are pointed out.

文章介绍了基于DSP的空间矢量调制、滞环电流控制、单周控制、滑模控制、无差拍控制、重复控制、预测控制、模糊控制以及人工神经网络控制这几种APF控制方案的基本原理,指出了它们各自的优缺点。

The objective is, based on the classification of airspace, to establish an En-route Control Area, Terminal/Approach Control Area, Airdrome Tower Control Area three-grade air traffic control areas;and then to establish an En-route Air Traffic Control Center, Terminal/Approach Air Traffic Control Center, Airdrome Tower Control Center three-grade air traffic control organization;To establish a reasonable backup mechanism and reduce the number of En-route Air Traffic Control Centers, finally to improve the quality of air traffic services.

本文系统地阐述了对管制区域重组战略目标所涉及的各子系统的考虑,重点分析了民航空中交通管理系统的运行体制、文化重组,并对战略实施过程进行了设计。空中交通管制区域的重组战略问题必须抛开部门利益的制约,站在国家利益的高度上,宏观长远地谋划。

The biomechanical tests showed that two kinds of artificial bones had not significant difference on compressive strength and Young\'s modulus(P>0.05),while the flexural strength of nano-nacre artificial bone was less than the control group(P<0.05).3.The results of CCK-8 showed that the difference were not significant in each group,the proliferation of osteoblast reached the peak at the 5th day;7 days after being co-cultured,the total protein content of study group was higher than control group and blank group(P<0.05),while the difference between control group and blank group was not significantP>0.05The difference of alkaline phosphatase activities among three groups was not significant(P>0.05The SEM view showed that osteoblast attached and grew well in two kinds of artificial bone.4.X-ray photography showed that two kinds of powder started to degrade in 2 weeks;this phenomenon became more appear in 4 weeks,nano-nacre powder degraded faster than micron-nacre powder,while the hole shadow was easy to be found;in 8 weeks,all the femoral holes recovered and returned to normal bone mineral density in all groups.Analysis of tetracycline fluorescent double marks in the hard tissue grinding slices indicated that new bone grew fastest around the bone defect area in study group,while most slowly in blank groupP<0.05 SEM(scanning electron microscope observation showed that nano-nacre powder degraded more quickly.The same result can be found through the demineralized sections morphometric analysis,and both of the composite artificial bones made from those two kinds of nacre powder had the good connection with the adjacent tissue in rats body without apparent inflammatory response.5.X-ray photography showed that rabbit\'s bone defects healed faster in study group since NNAB implanted than in control group since MNAB implanted.At 24 weeks after operation,bone density in radial defects had nearly accessed to the normal area,while lower in control group,and turned up nonunion in blank group;The checking of BMD showed that results in study group were higher than those in control group at 8,16 and 24 week(P<0.05), and the difference between the BMD values in study group at 24 week and those in blank group was not significant(P>0.05).The gross specimens showed satisfactory histocompatibility both in study group and in control group,with bone tissue growing from two sides into the center of implanted materials; Normal slices in HE stain and hard tissue grinding slices in Stevenel\'s blue/Van Geison\'s picro-fuchsin stain showed that the bone growth tendency was better in study group than that in control group,and the medullary cavity had been penetrated to the implanted materials in study group at 24 week;Analysis of tetracycline fluorescent double marks in the hard tissue grinding slices indicated that new bone in both groups grew fastest 8 weeks after surgery,while slow down at 16 week.

纳米珍珠层/消旋聚乳酸复合人工骨与微米珍珠层/消旋聚乳酸复合人工骨分别与成骨细胞共培养后,其各时间点CCK-8法检测值与空白对照无显著差异(P>0.05),成骨细胞均在第5天达到增殖高峰期;培养7天后,实验组细胞蛋白含量高于对照组及空白组(P<0.05),后两者之间则无显著差异P>0.05碱性磷酸酶活性在三组间均无显著差异(P>0.05电镜下可见成骨细胞在两种人工骨上都有良好生长贴附能力。4.X-ray显示两种粉体在大鼠股骨骨洞植入第2周时都开始出现了降解,第4周时更为明显,纳米珍珠层粉较之微米珍珠层粉降解更快,而空白对照组骨洞阴影仍可见,至8周时,则所有组骨洞均己闭合修复,X-ray下已不可见原钻孔痕迹,恢复正常骨质密度;硬组织磨片四环素荧光双标记结果显示纳米珍珠层粉植入组较其余两组在骨缺损区周围新骨生长速度更快,空白组速度最慢P<0.05电镜观察及常规脱钙切片亦可见到纳米粉体降解较快;由以上两种原材料制得的纳米珍珠层/消旋聚乳酸复合人工骨与微米珍珠层/消旋聚乳酸复合人工骨在大鼠体内均与周围组织结合良好,无明显炎症反应。5.X-ray显示纳米珍珠层/消旋聚乳酸复合人工骨植入兔桡骨缺损区后其骨愈合速度较对照组微米珍珠层/消旋聚乳酸复合人工骨植入的快,至植入术后24周,实验组骨缺损区接近正常骨密度,对照组骨缺损区密度较低,空白组则呈现骨不连状态;骨密度测量结果显示术后8周、16周、24周实验组的骨密度值高于对照组(P<0.05,24周实验组的骨密度值与术前所测得的正常值无显著性差异P>0.05动物取材大体所见均显示组织相容性良好,骨组织逐渐由植入材料两端向中央生长;常规切片HE染色及硬组织磨片Stevenel\'s blue/Van Geison\'s picro-fuchsin联合染色均可见实验组骨缺损区长势优于对照组,至术后24周,实验组骨髓腔与材料已呈相交通状;硬组织磨片荧光显微镜下观察,两组材料在术后8周处于骨生长最快速时期,16周时速度开始减慢,术后4、8、16周时实验组的新骨生长速度均较对照组的快

This chapter, by using the theory of public interests of the government control, control-capture theory, the theoretical model of the government control, the minimum government control theory construed the basic contents covered by the government control, and discussed the interactivity and the nonnegligible effects of the government control and the industrial development model. Theses theories provide the convictive constructions to some practical economic problems that cannot be satisfactorily constructed by the traditional economic theories. Thus it makes possible for us to look on the reasons for control rules formulated by the government and some other institutional problems in the industrial evolvement, and analyze the costs of the government control and the restrictive factors and significances of the institutional changes whereof in a never-before-used angle.

第二章分别从政府管制的公共利益论、管制俘获理论、政府管制的理论模型、最小政府管制理论等方面解释了政府管制所涵盖的基本内容,探讨了政府管制与产业发展模式之间的的相互关联和不可忽视的影响,这些理论对许多传统的经济理论难于很好地解释的经济现实问题给予了具有说服力的解释,使我们能够以新的视角来看待产业演进中由政府建立管制规则的理由和其他一些制度问题,分析政府管制的成本及其制度变革的制约因素和意义。

boiler is a important power equipment,the require is to provide qualified vapour,let the amount of vapour maked by boiler suit for the load.because of this,every main parameter in the process of the product should be strict controlled.this paper is introduced same main control system in the process of boiler control、concentrate and disperse control system 、the characteristic and the develop of the MCGS compose status software.integrate with the technique of the boiler, discuss the single momentum, double momentum, three momentum boiler control system distinguishly.we think in the process of micro boiler control, three momentum control is the best choice,and has been well implemented in the water level mediation.further more,use the concentrate and disperse control and MCGS compose statue sofeware can achieve the control of the boiler,and can reach a fine effect..

锅炉是一个重要的动力设备,其要求是供给合格的蒸汽,使锅炉发气量适合负荷的需要。为此,生产过程的各个主要参数必须严格控制。本设计了研究锅炉控制过程的几个主要控制系统,以及集散控制系统和MCGS组态软件的特点和发展状况。结合锅炉的工艺情况,针对单冲量、双冲量、三冲量锅炉控制系统,对它们存在的利弊做出了比较和分析。结合生产实践,对三冲量的算法进行比较,认为在小型锅炉控制过程中,三冲量控制是最好的选择,并在水位调节中得到很好的应用。

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Celebrate
Lose Control
Control
Loss Of Control
Takin' Control
Let The Beat Control Your Body
P Control (Remix)
Control
Take Control
Out Of Control
推荐网络例句

I hope that this success is just the first in a long series.

我希望这只是成功的开始。

Three dimensional stresses on the interface of tire and soil, tire deflection and soil sinkage are measured.

测试轮胎——沙土界面上的三向应力、轮胎变形和沙土沉陷;建立考虑剪切应力对沙土承载特性产生影响的车轮牵引性能预测模型;分析车轮作用下土壤的纵向稳定性。

Sickle-cell disease features episodes called 'sickling crises'.

镰状细胞病发作的特点所谓' sickling危机'。