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The present invention relates to a process for rapid solution synthesis of a peptide, the process comprising repetitive cycles of steps-: a coupling step, using an excess of an activated carboxylic component to acylate an amino component, a quenching step in which a scavenger is used to remove residual activated carboxylic functions, wherein the scavenger may also be used for deprotection of the growing peptide, one or more aqueous extractions and optionally, a separate deprotection step, followed by one or more aqueous extractions, characterised in that the process comprises at least one step, referred to as step, in which an amine or a thiol comprising a free anion or a latent anion is used as a scavenger of residual activated carboxylic functions.

本发明涉及快速溶液合成肽的方法,该方法包括步骤-的重复循环:偶联步骤,使用过量的活化羧基成分酰化氨基成分,淬灭步骤,在该步骤中使用清除剂除去残余的活化羧基官能团,其中该清除剂还可以用于使生长中的肽去保护,一或多个水抽提和任选地,独立的去保护步骤,之后进行一或多次水抽提,其特征在于该方法包括至少一个步骤,称作步骤,在该步骤中包含自由阴离子或潜阴离子的胺或硫醇用作残余活化羧基官能团的清除剂。

After the 7/7 bombings in London, the "spirit of the Blitz" was referred to ad nauseam by press and public.

在伦敦七七事件后,报纸与公众都过度地提起"伦敦大轰炸的精神"。

He also referred to provision of $500 million by ADB and $1.4 billion by World Bank and the Chinese offer for investment.

他还提到提供5亿美元由亚行和14亿美元由世界银行和中国提供的投资环境。

Imports under current and minimum access commitments established as part of a concession referred to in paragraph 1 above shall be counted for the purpose of determining the volume of imports required for invoking the provisions of subparagraph 1 and paragraph 4, but imports under such commitments shall not be affected by any additional duty imposed under either subparagraph 1 and paragraph 4 or subparagraph 1 and paragraph 5 below.

为确定援引第1款项和第4款的规定所需的进口量,应计入确定为以上第1款所指减让一部分的现行和最低准入承诺下的进口,但是此类承诺下的进口不得受到根据第1款项和以下第4款或根据第1款项和以下第5款征收的任何附加关税的影响。

According to the above referred quantitative standard as an HEDC and stabilityrequirement, 1,2,3,4,5,6,7,8-octanitroadamantane, 1,2,3,4,5,6,7,8,9-nonanitroadamantan-e and 1,2,3,4,5,6,7,8,9,10-decanitroadamantane are worth recommending as potentialHEDCs, and this denies the foreigners conclusion obtained from group additivity thatthe PNA with 11 nitro groups is the target compound.

按照前述HEDC的定量标准和稳定性要求,发现1,2,3,4,5,6,7,8-八硝基金刚烷、1,2,3,4,5,6,7,8,9-九硝基金刚烷和1,2,3,4,5,6,7,8,9,10-十硝基金刚烷三种化合物是值得推荐的潜在HEDC,从而否定了国外前人由基团加和法得出的十一硝基金刚烷是PNAs系列最佳HEDC目标物的结论。

This latter method of mapping the linear address space is commonly referred to as virtual memory or demand-paged virtual memory.

当内存已满,无法读入的时候,中断处理程序会根据内存的使用情况来决定把那个页置换出内存

Together, these four planets are sometimes referred to as the Jovian planets, where Jovian is the adjectival form of Jupiter.

地球是众所周知的天文学家古代的时候,是与神话和宗教信仰的许多文化。

In such cases, the therapy that is added to enhance the effects of the primary therapy is referred to as adjuvant therapy.

在这种情况下,治疗方法是补充,以提高效果的主要疗法是被称为辅助疗法。

The money to change the specifications referred to as "the admissibility of the project,"

能拿到钱的规格变更称为「受理项目」, 87。

The process itself is referred to as adventive embryogenesis.

其过程本身称为不定胚胎发生。

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On closer examination, though, this is not a vote for multilateralism but just the opposite.

仔细审视后我们发现,这并非是对多边主义投出的赞成票,而是恰好相反。

Uncovering their weak spots, so I can defeat them.

揭露出他们的弱点,这样我就可以打败他们了。

Methyl bromides, in C_(3v) symmetry, have been extensively studied at their first absorption A-band because the behavior of these molecules can be used as a prototype for depicting numerous types of photodissociations in a variety of polyatomic molecules.

例如,有很多研究报道了C_(3v)对称的溴甲烷等分子在第一吸收带的光解,这是因为其光解行为可以作为理解其它多原子分光解的原型。