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In some cases, its epimer 4 was also obtained. 22 compounds were synthesized, among them 18 were new.3. Using the intramolecular Pictet-Spengler reaction to form the pentacyclic skeleton of Et-743, the byproducts 25 were obtained under various conditions. The structures of them were determined to be 1, 2-dihydro-isoquinoline compounds, and the mechanism of the reaction was proposed.B. The synthesis of the analogs of Et-743Because of the failure of removing the protective groups in compounds 14, the synthetic strategy was adjusted.

对于苄基保护的羟基化合物13a，顺利得到化合物30，然后与不同的羧酸反应得到18个酯化合物33-50；对于苄氧羰基保护的氨基化合物13b，由于脱除保护基的化合物31在空气中不稳定，所以我们采取不经分离纯化，直接与羧酸反应得到酰胺化合物53-62，然后再分别对其C-21位的羰基进行还原氰基化，得到10个酰胺目标化合物63-72，另外，我们还对羟基转化为氨基的反应进行了探索。3。

Based on the application comprehensive of the shield,equipotential bonding and surge protective device, the combination protection of the automatic system is realized.

综合应用屏蔽、等电位连接和电涌保护器等基本防护措施，实现了自动化系统的雷电综合防护。

In 2005, we made another joint venture company Shanghai Hanhong Plus stationery Co., Ltd. with a famous enterprise- PLUS Japan, which is well known in this line. SHP is specialized in producing recycle paper file. This product is very strong and erective, easily made, can be printed into different design and color. Furthermore, it is a kind of environment protective products, which is low-energy expending, less polluting. This introduction of the project fills the blank of domestic market in China.

2005年与日本PLUS公司合资组建上海汉宏普乐士文具有限公司，上海汉宏普乐士文具有限公司是国内第一家生产环保型再生纸文件夹的专业型公司，建设节约性中国、环保性社会是当代中国坚持可持续发展、创建和谐社会的社会主旋律，环保型再生纸文件夹因应社会发展的潮流，产品一上市，已成为各地政府机关、企事业单位、学校、医院、银行等单位采购的指定产品。

Objective To observe the protective effects on muscle atrophy and function changes with exercise training of lower limb muscular strength and bicycle ergometer during 30 d -6° head-down bed rest.

目的观察下肢肌力训练方法和功率车训练方法对30d-6°头低位卧床引起的下肢肌肉萎缩和功能改变的防护效果。

Coclusion These results demonstrated that the rSpaA-N is a protective antigen of Erysipelothrix rhusiopathiae serotype 2 strains, and might be a useful vaccine candidate against swine erysipelas.

本研究结果表明rSpaA-N具有良好的免疫保护作用，可以作为猪丹毒亚单位疫苗。

The ash bark extract, rich in fraxin and esculin, decreases the permeability of blood capillaries, conferring a vasculo-protective action.

秦皮提取物含有丰富的秦皮苷和秦皮甲素，能够降低毛细血管的渗透性，具有保护血管的作用。

Protective effect of cholinergic anti-inflammatory pathway against acute esophagitis in rats.

胆碱能抗炎通路对急性食管炎大鼠的保护作用。

The corrosion stresses associated with a particular environment or corrosivity category represent one essential parameter governing the selection of protective paint systems.

腐蚀应力在特定的环境或者腐蚀种类下表现出来的一个基本参数决定了选择哪种防护体系。

Methods Observe the influence of temperature, acidity and alkalinity as well as protective additive on activity of soybean esterase.

分别测定不同温度、不同酸碱度和不同保护剂对大豆酯酶酶活力的影响。

Objective To study the protective function of estradiol after cerebral ischemia reperfusion and its effect on the expression of GDNF.

目的 探讨大鼠局灶脑缺血再灌注后雌二醇的保护作用及其对胶质细胞源性神经生长因子表达的影响。

Panorama Many people are dancing in a large sitting room.

在一个大客厅里，许多人在跳舞。

We fully understand how a microwave oven cooks food, it is first necessary to talk ...

我们充分理解一个微波炉煮的食物，这是首先要谈。。。